(superl.) Large in bulk, or composed of large parts or particles; of inferior quality or appearance; not fine in material or close in texture; gross; thick; rough; -- opposed to fine; as, coarse sand; coarse thread; coarse cloth; coarse bread.
(1) Epithelial thymoma is characterized by coarse-fiber stroma, perivascular grouping of cell elements and the lack of glycogen in them.
(2) Foveal involvement included coarse foveal granularity, thinning of the foveal retinal pigment epithelium, increasing encirclement of the fovea with focal areas of atrophy, and minimal macular drusen.
(3) In 11 of these 20 patients, visual sensitivity to detail of medium coarseness was markedly degraded, even though sensitivity to both coarse and fine detail was unimpaired.
(4) In it he translated Trump’s coarse ramblings into charming straight talk and came up with the phrase “truthful hyperbole”, which captures brilliantly an approach to business and politics in which everything is the greatest, the most beautiful.
(5) Characteristic coarse facial features and shortness of stature were observed in all cases.
(6) The pulp cavity is reduced in size with age (maturation stage), in which the characteristic three vascular layers are changed into a one-layer coarse terminal capillary network which converges directly with the main venules.
(7) (3) Their operative findings were different from ordinary Graves' goiters in that colors of the goiter were yellow-red or gray-red, surface was rough and coarse, consistency was firm, and adhesions with the adjacent connective tissue were noted.
(8) Attempts were made to purify the LH-releasing substance extracted from the leaves of Avena sativa by means of two-step chromatographic procedures using a weakly acidic ion-exchange resin (CG-50,type II) and DEAE-Sephadex A-25 (coarse) with successful results.
(9) First-time measurements of the potentially toxic inorganic species of arsenic (arsenite and arsenate) have been obtained in fine (less than 2.5 microns AD) and coarse (greater than 2.5 microns AD) atmospheric particles in the Los Angeles area.
(10) An abnormal great number of microtubules and coarsed fibers were frequently randomly scattered throughout the cytoplasmic droplet.
(11) Motorized linear slides used as micromanipulators for biological use suffer from 3 problems: vibration at low speed, poor ergonomic design of the controller and slow coarse positioning.
(12) Each antibody stained 2 populations of cortical nonpyramidal neurons: (1) A small number of large, intensely stained cells that give rise to long, coarsely beaded processes; (2) a relatively large number of small, lightly stained cells that are embedded in dense plexuses of stained punctate profiles.
(13) In the Pagalunggan subdistrict, all females used uniodised salt with 17.6% using fine salt, 20% using coarse salt and the remainder using both fine and coarse salt.
(14) Thygeson's keratitis is characterized by a coarse punctate epithelial keratitis with almost no hyperaemia of the conjunctiva.
(15) The particles selected by CYBEST as "abnormal cells" at the stage of coarse scanning were examined by direct microscopy to determine whether they were actural cells or not.
(16) Fine wrinkling, coarse wrinkling, sallowness, looseness, and hyperpigmentation were significantly improved with tretinoin therapy.
(17) Coarse, linear densities are also observed, and pleural effusion is seen in many patients.
(18) Serves 4 100g butter, at room temperature 150g flour 50g ground almonds 30g suet 1 egg yolk 50g cooked chestnuts, chopped 5 tbsp chopped fresh thyme Salt and black pepper For the leeks 1kg leeks, trimmed 100g butter Salt and pepper 200ml double cream 1 tsp nutmeg 1 To make the crumble topping, work the butter into the flour until it resembles coarse breadcrumbs, then add the ground almonds and suet.
(19) 400g cooked or tinned butterbeans 1 tsp ground cumin 10ml lemon juice ¼ clove garlic, peeled and finely minced 1 small handful picked flat-leaf parsley, finely chopped 1 tbsp plain flour (gluten-free flour also works fine) 1 tsp salt 1 egg 1 spring onion, trimmed and finely sliced 50g breadcrumbs 100g feta (or other crumbly goat's or sheep's cheese) Put the butterbeans, cumin, lemon juice, garlic, parsley, flour, salt and egg in a food processor and blitz to a coarse paste: you don't want the mix fully pureed, otherwise the burgers will be too wet and will fall apart on the grill.
(20) In women who received free-silicone injections, coarse calcifications developed in three, and gross nodularity with calcified silicone granulomas developed in one.
Horny
Definition:
(superl.) Having horns or hornlike projections.
(superl.) Composed or made of horn, or of a substance resembling horn; of the nature of horn.
(superl.) Hard; callous.
Example Sentences:
(1) Digestion of cytoplasmic components of horny cells was observed by electron microscopy, but both cell membranes and desmosomes remained intact.
(2) Strains of C. albicans differing in their abilities to secrete proteinase in vitro and to produce germ tube were inoculated onto the skin surface of newborn mice, and the invasion of the yeast cells into the horny layer was examined by histological techniques.
(3) Morphologic features of Malassezia(M.) furfur in the horny layer from clinical lesions of tinea versicolor were examined by scanning electron microscopy and compared with the appearance of fungus in the horny layer from normal skin and in culture.
(4) The absolute concentrations of 8-Methoxypsoralen were estimated in the horny layer, epidermis and dermis.
(5) In the next stage, the roof consisting of the malpighian layers is disrupted, and the vesicular fluid comes into contact with the horny layer.
(6) The systematic evaluation of the original curves takes into consideration amplitude, angle of climb and medium route and results in a horny layer sample-obtained successively from one and the same horny layer strip-series test area-impressioned by individual and regional horny layer conditions.
(7) The nature of the horny layer which, as the uppermost barrier takes over the main part of the protective function of the skin against all locally applied substances, is shortly outlined.
(8) Removal of the horny layer decreased epidermal IL 1-like activity.
(9) The superficial dermis contained horny cysts, similar to those present on the cheeks.
(10) Munro's microabscess under the horny layer also included IFN-gamma producing cells.
(11) The fluid was obtained from the skin surface of female mongrel dogs by transcutaneous suction after removal of the horny substance.
(12) The mockery continued when he noted semi-automatics had only two purposes: to kill people, and to let their owners go to a shooting range, "yell yeehaw, and get all horny at the rapid fire and the burning vapor spurting from the end of the barrel".
(13) In both sites the plasma membranes of the horny cells were thickened and there was a cytoplasmic meshwork of microfibrils in the cells.
(14) Epithelial cells changing from the granular stage of differentiation to the horny stage are more numerous, and reveal sequential events of transformation in finer detail in the rumen epithelium than in other keratinizing epithelia thus far studied in the electron microscope.
(15) Yet there is Samantha, bawdy as the Wife of Bath, always cheerfully horny and materialistic, utterly without Calvinic redeeming qualities, living at last with her devoted younger boy toy in LA in the Sex and the City movie – finally leaving him because she is just not cut out to mix her driving, unmediated sexual energy with commitment.
(16) "Before you hit puberty, you have this growing, really urgent sense of horniness."
(17) This reflected enhanced permeability resulting from reduction of the horny layer to less than one-half its normal thickness.
(18) Remaining reactivity with antibodies, but not lectins, was almost completely abolished immediately before the final disintegration of the desmosome structure in the lower horny layer.
(19) The calcified concretions are also seen in the lymphatic capillaries, the intraepidermal sweat ducts and horny layer; at a site they perforate the epidermis and penetrate in a sweat pore.
(20) Elastic fibres were prominent in the upper dermis, the lower levels of the epidermis and in the hyperkeratotic horny layer.