(superl.) Large in bulk, or composed of large parts or particles; of inferior quality or appearance; not fine in material or close in texture; gross; thick; rough; -- opposed to fine; as, coarse sand; coarse thread; coarse cloth; coarse bread.
(1) Epithelial thymoma is characterized by coarse-fiber stroma, perivascular grouping of cell elements and the lack of glycogen in them.
(2) Foveal involvement included coarse foveal granularity, thinning of the foveal retinal pigment epithelium, increasing encirclement of the fovea with focal areas of atrophy, and minimal macular drusen.
(3) In 11 of these 20 patients, visual sensitivity to detail of medium coarseness was markedly degraded, even though sensitivity to both coarse and fine detail was unimpaired.
(4) In it he translated Trump’s coarse ramblings into charming straight talk and came up with the phrase “truthful hyperbole”, which captures brilliantly an approach to business and politics in which everything is the greatest, the most beautiful.
(5) Characteristic coarse facial features and shortness of stature were observed in all cases.
(6) The pulp cavity is reduced in size with age (maturation stage), in which the characteristic three vascular layers are changed into a one-layer coarse terminal capillary network which converges directly with the main venules.
(7) (3) Their operative findings were different from ordinary Graves' goiters in that colors of the goiter were yellow-red or gray-red, surface was rough and coarse, consistency was firm, and adhesions with the adjacent connective tissue were noted.
(8) Attempts were made to purify the LH-releasing substance extracted from the leaves of Avena sativa by means of two-step chromatographic procedures using a weakly acidic ion-exchange resin (CG-50,type II) and DEAE-Sephadex A-25 (coarse) with successful results.
(9) First-time measurements of the potentially toxic inorganic species of arsenic (arsenite and arsenate) have been obtained in fine (less than 2.5 microns AD) and coarse (greater than 2.5 microns AD) atmospheric particles in the Los Angeles area.
(10) An abnormal great number of microtubules and coarsed fibers were frequently randomly scattered throughout the cytoplasmic droplet.
(11) Motorized linear slides used as micromanipulators for biological use suffer from 3 problems: vibration at low speed, poor ergonomic design of the controller and slow coarse positioning.
(12) Each antibody stained 2 populations of cortical nonpyramidal neurons: (1) A small number of large, intensely stained cells that give rise to long, coarsely beaded processes; (2) a relatively large number of small, lightly stained cells that are embedded in dense plexuses of stained punctate profiles.
(13) In the Pagalunggan subdistrict, all females used uniodised salt with 17.6% using fine salt, 20% using coarse salt and the remainder using both fine and coarse salt.
(14) Thygeson's keratitis is characterized by a coarse punctate epithelial keratitis with almost no hyperaemia of the conjunctiva.
(15) The particles selected by CYBEST as "abnormal cells" at the stage of coarse scanning were examined by direct microscopy to determine whether they were actural cells or not.
(16) Fine wrinkling, coarse wrinkling, sallowness, looseness, and hyperpigmentation were significantly improved with tretinoin therapy.
(17) Coarse, linear densities are also observed, and pleural effusion is seen in many patients.
(18) Serves 4 100g butter, at room temperature 150g flour 50g ground almonds 30g suet 1 egg yolk 50g cooked chestnuts, chopped 5 tbsp chopped fresh thyme Salt and black pepper For the leeks 1kg leeks, trimmed 100g butter Salt and pepper 200ml double cream 1 tsp nutmeg 1 To make the crumble topping, work the butter into the flour until it resembles coarse breadcrumbs, then add the ground almonds and suet.
(19) 400g cooked or tinned butterbeans 1 tsp ground cumin 10ml lemon juice ¼ clove garlic, peeled and finely minced 1 small handful picked flat-leaf parsley, finely chopped 1 tbsp plain flour (gluten-free flour also works fine) 1 tsp salt 1 egg 1 spring onion, trimmed and finely sliced 50g breadcrumbs 100g feta (or other crumbly goat's or sheep's cheese) Put the butterbeans, cumin, lemon juice, garlic, parsley, flour, salt and egg in a food processor and blitz to a coarse paste: you don't want the mix fully pureed, otherwise the burgers will be too wet and will fall apart on the grill.
(20) In women who received free-silicone injections, coarse calcifications developed in three, and gross nodularity with calcified silicone granulomas developed in one.
Nasty
Definition:
(superl.) Offensively filthy; very dirty, foul, or defiled; disgusting; nauseous.
(superl.) Characterized by obcenity; indecent; indelicate; gross; filthy.
Example Sentences:
(1) How does it stack up against the competition – and are there any nasties in the small print?
(2) Admirably, Clinton kept her cool throughout, particularly Trump when spoke over her to call her “such a nasty woman”.
(3) He wanted to stay on longer than the traditional retirement age but became involved in a nasty spat with the then-chairman, Peter Sutherland.
(4) It is the latest attack on the government from the Hungarian economist, whose previous criticism of David Cameron's "nasty" looking restrictions on benefits for foreigners led the angry prime minister to lodge a formal complaint.
(5) Protesters waved banners with slogans such as “Special relationship, just say no” and “Nasty women unite”.
(6) The examples I have quoted are the tip of a very large and very nasty iceberg.
(7) In short, it is alleged that under his rule Sri Lanka is becoming a nasty, authoritarian quasi-rogue banana republic.
(8) Patterson agrees that it’s all much more controlled now, but she also wonders whether at times the media can be too negative, doomy, and sometimes downright nasty.
(9) And I’m sorry, that will come before any internal party-political issue and I think I should be able to adopt that position without being attacked, without being subject to a nasty troll-form of politics.” On Tuesday the prime minister, David Cameron, promised to publish a comprehensive strategy on Syria in the form of a written response to a report by the foreign affairs select committee, which concluded that the government had failed to make the case for extending airstrikes.
(10) Al-Azhar, the Sunni Muslim world’s leading centre of Islamic learning, called on Muslims to “ignore the nasty frivolity” of the latest edition.
(11) He was followed by Theresa May, who 13 years ago had warned that many voters thought the Conservatives were the “nasty party”, but who now pledged to clamp down on the rights of asylum seekers, and renewed her commitment to cut net migration to below 100,000 in terms so harsh that she was widely condemned even by her allies.
(12) I think it probably gave me a sense of self and self-protection that has been very useful, and I possibly have had less nasty moments than a lot of other women.
(13) Dr Rosemary Gillespie was the object of a “nasty, vindictive and sustained campaign of bullying” from her second day in the job at the UK’s biggest HIV charity, the tribunal heard.
(14) It had a “flat, nasty” ring to it, she says, which she has since “analysed like a Rubik’s cube; I have turned it every which way.
(15) Updated at 2.10pm BST 1.47pm BST Over to America, where the latest productivity figures confirm that the US economy took a nasty jolt over the winter, when bad weather gripped the country.
(16) It doesn't have to be bloody, it doesn't have to be nasty, but it does have to be fought."
(17) That was the one surprise in the budget – apart from the fine print of the nasties.
(18) Because the nastiness on our doorstep has piled too high for too long, and I just want to get out of the house.
(19) Southampton 3-0 Vitesse | Europa League third qualifying round match report Read more Even more damagingly for West Ham, they lost Enner Valencia to a potentially nasty knee injury in the first half after he caught his leg in the turf.
(20) They orginally had lofty ambitions of talking about the economy but since they have lost that argument so catastrophically, they have reached for the Ukip playbook to create fictitious stories to scare people about immigrants and release video nasties about Turkish people”.