(superl.) Large in bulk, or composed of large parts or particles; of inferior quality or appearance; not fine in material or close in texture; gross; thick; rough; -- opposed to fine; as, coarse sand; coarse thread; coarse cloth; coarse bread.
(1) Epithelial thymoma is characterized by coarse-fiber stroma, perivascular grouping of cell elements and the lack of glycogen in them.
(2) Foveal involvement included coarse foveal granularity, thinning of the foveal retinal pigment epithelium, increasing encirclement of the fovea with focal areas of atrophy, and minimal macular drusen.
(3) In 11 of these 20 patients, visual sensitivity to detail of medium coarseness was markedly degraded, even though sensitivity to both coarse and fine detail was unimpaired.
(4) In it he translated Trump’s coarse ramblings into charming straight talk and came up with the phrase “truthful hyperbole”, which captures brilliantly an approach to business and politics in which everything is the greatest, the most beautiful.
(5) Characteristic coarse facial features and shortness of stature were observed in all cases.
(6) The pulp cavity is reduced in size with age (maturation stage), in which the characteristic three vascular layers are changed into a one-layer coarse terminal capillary network which converges directly with the main venules.
(7) (3) Their operative findings were different from ordinary Graves' goiters in that colors of the goiter were yellow-red or gray-red, surface was rough and coarse, consistency was firm, and adhesions with the adjacent connective tissue were noted.
(8) Attempts were made to purify the LH-releasing substance extracted from the leaves of Avena sativa by means of two-step chromatographic procedures using a weakly acidic ion-exchange resin (CG-50,type II) and DEAE-Sephadex A-25 (coarse) with successful results.
(9) First-time measurements of the potentially toxic inorganic species of arsenic (arsenite and arsenate) have been obtained in fine (less than 2.5 microns AD) and coarse (greater than 2.5 microns AD) atmospheric particles in the Los Angeles area.
(10) An abnormal great number of microtubules and coarsed fibers were frequently randomly scattered throughout the cytoplasmic droplet.
(11) Motorized linear slides used as micromanipulators for biological use suffer from 3 problems: vibration at low speed, poor ergonomic design of the controller and slow coarse positioning.
(12) Each antibody stained 2 populations of cortical nonpyramidal neurons: (1) A small number of large, intensely stained cells that give rise to long, coarsely beaded processes; (2) a relatively large number of small, lightly stained cells that are embedded in dense plexuses of stained punctate profiles.
(13) In the Pagalunggan subdistrict, all females used uniodised salt with 17.6% using fine salt, 20% using coarse salt and the remainder using both fine and coarse salt.
(14) Thygeson's keratitis is characterized by a coarse punctate epithelial keratitis with almost no hyperaemia of the conjunctiva.
(15) The particles selected by CYBEST as "abnormal cells" at the stage of coarse scanning were examined by direct microscopy to determine whether they were actural cells or not.
(16) Fine wrinkling, coarse wrinkling, sallowness, looseness, and hyperpigmentation were significantly improved with tretinoin therapy.
(17) Coarse, linear densities are also observed, and pleural effusion is seen in many patients.
(18) Serves 4 100g butter, at room temperature 150g flour 50g ground almonds 30g suet 1 egg yolk 50g cooked chestnuts, chopped 5 tbsp chopped fresh thyme Salt and black pepper For the leeks 1kg leeks, trimmed 100g butter Salt and pepper 200ml double cream 1 tsp nutmeg 1 To make the crumble topping, work the butter into the flour until it resembles coarse breadcrumbs, then add the ground almonds and suet.
(19) 400g cooked or tinned butterbeans 1 tsp ground cumin 10ml lemon juice ¼ clove garlic, peeled and finely minced 1 small handful picked flat-leaf parsley, finely chopped 1 tbsp plain flour (gluten-free flour also works fine) 1 tsp salt 1 egg 1 spring onion, trimmed and finely sliced 50g breadcrumbs 100g feta (or other crumbly goat's or sheep's cheese) Put the butterbeans, cumin, lemon juice, garlic, parsley, flour, salt and egg in a food processor and blitz to a coarse paste: you don't want the mix fully pureed, otherwise the burgers will be too wet and will fall apart on the grill.
(20) In women who received free-silicone injections, coarse calcifications developed in three, and gross nodularity with calcified silicone granulomas developed in one.
Rude
Definition:
(superl.) Characterized by roughness; umpolished; raw; lacking delicacy or refinement; coarse.
(superl.) Unformed by taste or skill; not nicely finished; not smoothed or polished; -- said especially of material things; as, rude workmanship.
(superl.) Of untaught manners; unpolished; of low rank; uncivil; clownish; ignorant; raw; unskillful; -- said of persons, or of conduct, skill, and the like.
(superl.) Violent; tumultuous; boisterous; inclement; harsh; severe; -- said of the weather, of storms, and the like; as, the rude winter.
(superl.) Barbarous; fierce; bloody; impetuous; -- said of war, conflict, and the like; as, the rude shock of armies.
(superl.) Not finished or complete; inelegant; lacking chasteness or elegance; not in good taste; unsatisfactory in mode of treatment; -- said of literature, language, style, and the like.
Example Sentences:
(1) You need a little moleskine, to write rude ideas... Mel No, I’ve just started recycling them.
(2) I categorically never said that ‘Britain has so many paedophiles because it has so many Asian men’.” She added that it was “totally untrue” that she had threatened to “take this inquiry down with me”, and absolutely rejected being rude and abusive to junior staff.
(3) For a while yesterday, Hazel Blears's selfishly-timed resignation with her rude "rock the boat" brooch send shudders of revulsion through some in the party.
(4) Like low blood pressure after a heart attack, then, cheap oil should arguably be regarded not as a sign of rude health, but rather as a consequence of malaise.
(5) This country has had a free press for the last 300 years, that has been irreverent and rude as my website is and holding public officials to account.
(6) We had some memorable encounters and he was very rude to me.
(7) He privately told the privy counsellors' committee of inquiry set up to review the events leading up to the invasion: "If I may be very frank and rather rude, you had to keep the ball in the air with the Argentines.
(8) There will be dialogue and discussions about what works, rather than rude surprises that backfire.
(9) As Google states, it is definitely in the company’s best interest to get its first smartglass customers to behave, as “breaking the rules or being rude will not get businesses excited about Glass and will ruin it for other Explorers”.
(10) I think, in all honestly, if I could be Bradley Whitford I would be very, very happy.” He becomes almost drawlingly dreamy, rolling his “r”s as he leans against the warm oolite cliffs of this Jurassic Coast, until rudely interrupted by me, asking whether there’s talk of a Broadchurch 3 .
(11) If someone was rude to you, you were rude back to them.
(12) Brexiters face rude awakening on immigration, says ex-minister Read more The problem is, there is nothing on the horizon to suggest that achieving any significant reduction in immigration is achievable or even desirable.
(13) He repeatedly argued that his south London upbringing meant he was rude to people who were rude to him and said Jones needed to “get over it”, although he said that he was unaware of his colleague’s history of illness.
(14) When he sees what he's inherited, he may get a rude awakening.
(15) Having reassured ourselves that we’re justified in “holding them to account” and “having robust debates” and “speaking truth to power”, we’re now just flat-out rude to their faces?
(16) But the fact that there is a serious disagreement between Zimbabwe and the United Kingdom does not mean that you should then be discourteous or rude."
(17) I said to them afterwards: ‘If you’re not on it 100% in this league, you’ll get a rude awakening.’’” Albion must be sick of the sight of QPR and Charlie Austin in particular.
(18) I can think of hordes of politicians who look worse and "weirder", with wet little pouty-mouths, strange shiny skin, mad glaring eyes, deathly pale demeanour, blank gaze and an unhealthy quantity of fat (I can't name them, because it's rude to make personal remarks), and I don't hear anyone calling them "weird", or mocking their looks, except for the odd bold cartoonist, but when it comes to Miliband , it's be-as-rude-as-you-like time.
(19) She said something rude, and I picked up her arm and I bit it!
(20) So instead of asking for anything on her birthday, she gives her friends presents, and she regularly sticks bullies and rude policemen in trees.