(superl.) Large in bulk, or composed of large parts or particles; of inferior quality or appearance; not fine in material or close in texture; gross; thick; rough; -- opposed to fine; as, coarse sand; coarse thread; coarse cloth; coarse bread.
(1) Epithelial thymoma is characterized by coarse-fiber stroma, perivascular grouping of cell elements and the lack of glycogen in them.
(2) Foveal involvement included coarse foveal granularity, thinning of the foveal retinal pigment epithelium, increasing encirclement of the fovea with focal areas of atrophy, and minimal macular drusen.
(3) In 11 of these 20 patients, visual sensitivity to detail of medium coarseness was markedly degraded, even though sensitivity to both coarse and fine detail was unimpaired.
(4) In it he translated Trump’s coarse ramblings into charming straight talk and came up with the phrase “truthful hyperbole”, which captures brilliantly an approach to business and politics in which everything is the greatest, the most beautiful.
(5) Characteristic coarse facial features and shortness of stature were observed in all cases.
(6) The pulp cavity is reduced in size with age (maturation stage), in which the characteristic three vascular layers are changed into a one-layer coarse terminal capillary network which converges directly with the main venules.
(7) (3) Their operative findings were different from ordinary Graves' goiters in that colors of the goiter were yellow-red or gray-red, surface was rough and coarse, consistency was firm, and adhesions with the adjacent connective tissue were noted.
(8) Attempts were made to purify the LH-releasing substance extracted from the leaves of Avena sativa by means of two-step chromatographic procedures using a weakly acidic ion-exchange resin (CG-50,type II) and DEAE-Sephadex A-25 (coarse) with successful results.
(9) First-time measurements of the potentially toxic inorganic species of arsenic (arsenite and arsenate) have been obtained in fine (less than 2.5 microns AD) and coarse (greater than 2.5 microns AD) atmospheric particles in the Los Angeles area.
(10) An abnormal great number of microtubules and coarsed fibers were frequently randomly scattered throughout the cytoplasmic droplet.
(11) Motorized linear slides used as micromanipulators for biological use suffer from 3 problems: vibration at low speed, poor ergonomic design of the controller and slow coarse positioning.
(12) Each antibody stained 2 populations of cortical nonpyramidal neurons: (1) A small number of large, intensely stained cells that give rise to long, coarsely beaded processes; (2) a relatively large number of small, lightly stained cells that are embedded in dense plexuses of stained punctate profiles.
(13) In the Pagalunggan subdistrict, all females used uniodised salt with 17.6% using fine salt, 20% using coarse salt and the remainder using both fine and coarse salt.
(14) Thygeson's keratitis is characterized by a coarse punctate epithelial keratitis with almost no hyperaemia of the conjunctiva.
(15) The particles selected by CYBEST as "abnormal cells" at the stage of coarse scanning were examined by direct microscopy to determine whether they were actural cells or not.
(16) Fine wrinkling, coarse wrinkling, sallowness, looseness, and hyperpigmentation were significantly improved with tretinoin therapy.
(17) Coarse, linear densities are also observed, and pleural effusion is seen in many patients.
(18) Serves 4 100g butter, at room temperature 150g flour 50g ground almonds 30g suet 1 egg yolk 50g cooked chestnuts, chopped 5 tbsp chopped fresh thyme Salt and black pepper For the leeks 1kg leeks, trimmed 100g butter Salt and pepper 200ml double cream 1 tsp nutmeg 1 To make the crumble topping, work the butter into the flour until it resembles coarse breadcrumbs, then add the ground almonds and suet.
(19) 400g cooked or tinned butterbeans 1 tsp ground cumin 10ml lemon juice ¼ clove garlic, peeled and finely minced 1 small handful picked flat-leaf parsley, finely chopped 1 tbsp plain flour (gluten-free flour also works fine) 1 tsp salt 1 egg 1 spring onion, trimmed and finely sliced 50g breadcrumbs 100g feta (or other crumbly goat's or sheep's cheese) Put the butterbeans, cumin, lemon juice, garlic, parsley, flour, salt and egg in a food processor and blitz to a coarse paste: you don't want the mix fully pureed, otherwise the burgers will be too wet and will fall apart on the grill.
(20) In women who received free-silicone injections, coarse calcifications developed in three, and gross nodularity with calcified silicone granulomas developed in one.
Sackcloth
Definition:
(n.) Linen or cotton cloth such as sacks are made of; coarse cloth; anciently, a cloth or garment worn in mourning, distress, mortification, or penitence.
Example Sentences:
(1) In that same National season, he teamed with Simon Callow (as Face) and Josie Lawrence (as Doll Common) in a co-production by Bill Alexander for the Birmingham Rep of Ben Jonson’s trickstering, two-faced masterpiece The Alchemist ; he was a comically pious Subtle in sackcloth and sandals.
(2) The matrix attached to the growth substratum had a "sackcloth-like" structure as seen by phase contrast, immunofluorescence, and scanning electron microscopy, and it had a vaguely filamentous ultrastructure similar to that seen in intact cell layers.
(3) Especially when Beyoncé on downtime is still a stunningly beautiful woman – it would take sackcloth and ashes to make her look truly awful.
(4) One would have thought that the Argentinian bishops would have seized the opportunity to call for pardon for themselves and put on sackcloth and ashes as the sentences were announced in Córdoba but that has not so far happened.
(5) Poor old Nick Clegg knows it’s all over but he hopes a mixture of sackcloth and ashes and disowning his past will save him.
(6) On our conditions, of course, in sackcloth and ashes: a small price to pay to save the European dream.
(7) The argument that recommends ankle-length sackcloth in order to allow men to get on with the real work?
(8) However, since this is the [Catholic church’s] jubilee year of mercy , I have forgiven these inspectors for their misjudgments, and they did not have to wear sackcloth and ashes all the way to Ofsted headquarters in London.
(9) An earthquake has happened in British politics and I did not foresee it,” he said, sackcloth and ashes just out of shot on College Green.
(10) Famed for his self-denial, Severinus is said to have slept on sackcloth.