(v. t.) To make coarse or vulgar; as, to coarsen one's character.
Example Sentences:
(1) Lesions observed in the small bowel included fixity of bowel loops, thickening of the wall, coarsening of the mucosal pattern and strictures.
(2) They hang pretty strangely, these garments of Britannia: if our decline is down to the loss of empire, how can we call that a coarsening?
(3) Deposits of slightly coarsened reaction product (RP) appeared and accumulated on the abluminal surface.
(4) Radiographic appearances consisted of minimal trabecular coarsening in the patella of nearly normal size and progressed to considerable cortical thickening and osteoblastic remodeling in a dramatically enlarged patella.
(5) Dilatation of the endoplasmic reticulum cavities, an increase in the number of ribosomes near bacteria, deformation of mitochondria and coarsening of cristae were revealed in phagocytosis of Past.
(6) The main side-effects were fluid retention (in eight) and hypertrichosis (in ten), accompanied in some by a peculiar coarsening of the facial features.
(7) Whipple's disease is characterized morphologically by macrophages in the small intestine which store PAS-postive material, as well as coarsening and atrophy of the intestinal villi, with pseudocystic cavitations.
(8) "When literature exists, perhaps we do not notice how important it is, but when it does not exist, our lives become coarsened and brutal.
(9) Acromegaly is characterized by coarsening of facial features, acanthosis nigricans, hypertrichosis and oily skin.
(10) At P 5, coarsened RP was diffusely observed on the luminal and abluminal surfaces.
(11) Gastroduodenoscopy then demonstrated duodenal polyps and massive coarsening of the gastric folds due to infiltration.
(12) The earliest radiological changes were found after six months, at the end of the second scintigraphic peak; they consisted of coarsening and blurring of the trabeculae, nonhomogeneous spotty mineralisation and endosteal scalloping.
(13) "What troubles me about Grand Theft Auto V," sighs Delingpole, "is not just the message it sends out to youngsters (drugs are cool; crime pays; violence is fun), but what it says about the coarsening, the decadence and the hopelessness of our modern culture."
(14) The tabloid newspapers, their "scurillity", are so "consonant with British decline … the general coarsening of British nature".
(15) Of course, cheap comparisons coarsen our collective conversation.
(16) Two investigators were asked to evaluate independently the echogenicity, coarsening and inhomogeneity of the hepatic echo pattern in a semi-quantitative manner; they had no knowledge of the diagnosis and used the same apparatus.
(17) Osteomalacia presents radiographically as deossification, coarsening of the trabecular pattern, and pseudofractures.
(18) Sucralfate should also be evaluated in those difficult clinical conditions known to be resistant to any therapeutic attempt with currently available drugs, such as erosive varioliform gastritis and hypertrophic gastropathy with heavy inflammation of the mucosa and giant coarsening of the gastric rugae.
(19) Gradually he relaxed - and slightly coarsened - into the role his new admirers seemed to want, into a globetrotting, tax-exiled celebrity who told uproarious tales in funny foreign voices, into the Hercule Poirot film series, which allowed him painfully little range or scope.
(20) Widening of the diameter of the bone and loss of cortical medullary distinction with a mottled coarsening of the trabecular pattern are the most characteristic features.
Horny
Definition:
(superl.) Having horns or hornlike projections.
(superl.) Composed or made of horn, or of a substance resembling horn; of the nature of horn.
(superl.) Hard; callous.
Example Sentences:
(1) Digestion of cytoplasmic components of horny cells was observed by electron microscopy, but both cell membranes and desmosomes remained intact.
(2) Strains of C. albicans differing in their abilities to secrete proteinase in vitro and to produce germ tube were inoculated onto the skin surface of newborn mice, and the invasion of the yeast cells into the horny layer was examined by histological techniques.
(3) Morphologic features of Malassezia(M.) furfur in the horny layer from clinical lesions of tinea versicolor were examined by scanning electron microscopy and compared with the appearance of fungus in the horny layer from normal skin and in culture.
(4) The absolute concentrations of 8-Methoxypsoralen were estimated in the horny layer, epidermis and dermis.
(5) In the next stage, the roof consisting of the malpighian layers is disrupted, and the vesicular fluid comes into contact with the horny layer.
(6) The systematic evaluation of the original curves takes into consideration amplitude, angle of climb and medium route and results in a horny layer sample-obtained successively from one and the same horny layer strip-series test area-impressioned by individual and regional horny layer conditions.
(7) The nature of the horny layer which, as the uppermost barrier takes over the main part of the protective function of the skin against all locally applied substances, is shortly outlined.
(8) Removal of the horny layer decreased epidermal IL 1-like activity.
(9) The superficial dermis contained horny cysts, similar to those present on the cheeks.
(10) Munro's microabscess under the horny layer also included IFN-gamma producing cells.
(11) The fluid was obtained from the skin surface of female mongrel dogs by transcutaneous suction after removal of the horny substance.
(12) The mockery continued when he noted semi-automatics had only two purposes: to kill people, and to let their owners go to a shooting range, "yell yeehaw, and get all horny at the rapid fire and the burning vapor spurting from the end of the barrel".
(13) In both sites the plasma membranes of the horny cells were thickened and there was a cytoplasmic meshwork of microfibrils in the cells.
(14) Epithelial cells changing from the granular stage of differentiation to the horny stage are more numerous, and reveal sequential events of transformation in finer detail in the rumen epithelium than in other keratinizing epithelia thus far studied in the electron microscope.
(15) Yet there is Samantha, bawdy as the Wife of Bath, always cheerfully horny and materialistic, utterly without Calvinic redeeming qualities, living at last with her devoted younger boy toy in LA in the Sex and the City movie – finally leaving him because she is just not cut out to mix her driving, unmediated sexual energy with commitment.
(16) "Before you hit puberty, you have this growing, really urgent sense of horniness."
(17) This reflected enhanced permeability resulting from reduction of the horny layer to less than one-half its normal thickness.
(18) Remaining reactivity with antibodies, but not lectins, was almost completely abolished immediately before the final disintegration of the desmosome structure in the lower horny layer.
(19) The calcified concretions are also seen in the lymphatic capillaries, the intraepidermal sweat ducts and horny layer; at a site they perforate the epidermis and penetrate in a sweat pore.
(20) Elastic fibres were prominent in the upper dermis, the lower levels of the epidermis and in the hyperkeratotic horny layer.