(n.) A leader or chief; a conspicuous person, esp. a rich covetous person.
(n.) The axis on which the kernels of maize or indian corn grow.
(n.) A spider; perhaps from its shape; it being round like a head.
(n.) A young herring.
(n.) A fish; -- also called miller's thumb.
(n.) A short-legged and stout horse, esp. one used for the saddle.
(n.) A sea mew or gull; esp., the black-backed gull (Larus marinus).
(n.) A lump or piece of anything, usually of a somewhat large size, as of coal, or stone.
(n.) A cobnut; as, Kentish cobs. See Cobnut.
(n.) Clay mixed with straw.
(n.) A punishment consisting of blows inflicted on the buttocks with a strap or a flat piece of wood.
(n.) A Spanish coin formerly current in Ireland, worth abiut 4s. 6d.
(v. t.) To strike
(v. t.) To break into small pieces, as ore, so as to sort out its better portions.
(v. t.) To punish by striking on the buttocks with a strap, a flat piece of wood, or the like.
Example Sentences:
(1) This fusion protein exhibited an in vivo endonuclease activity which specifically cleaved the intron homing site within the intronless cob gene.
(2) All of the pdu mutations were located in a single region (41 map units) on the S. typhimurium chromosome between the his (histidine biosynthesis) and branch I cob (cobalamin biosynthesis) operons.
(3) The apoprotein of yeast cytochrome b is translated on mitochondrial ribosomes and coded for by a split gene which is located in the COB-BOX region on mitochondrial DNA.
(4) The large deletion M9391 in contrast accumulates a 13S RNA which probably results from transcription through the junction, which ligates sequences of the cob leader to sequences of the cob-oli1 intergenic spacer.
(5) One of these is the group II intron in the gene encoding apocytochrome b (cob: intron cobI1).
(6) The organization of the mitochondrial genomes of the F1 and succeeding backcross progenies was analyzed and compared with the progenitor RD-WF9 using probes derived from the S1 and S2 mitochondrial episomes, and probes containing the genes for cytochrome c oxidase subunit I (coxI), cytochrome c oxidase subunit II (coxII) and apocytochrome b (cob).
(7) The transfer of the upper nucleoside ligand of adenosylcobalamin to 2-mercaptoethanol is a very slow process; S-adenosyl-mercaptoethanol and cob(II)alamin are the final products of the reaction.
(8) The vitamin B12 auxotrophs were divided into two major phenotypic groups: Cob mutants, which could use cobinamide or vitamin B12 to grow on ethanolamine, and Cbl mutants, which could be supplemented only by vitamin B12.
(9) We made specific mutations in the internal guide sequence and the flanking exons of the fifth intron in the yeast mitochondrial gene for apocytochrome b (COB).
(10) Continuous registration of breath, ECG, O2 tension was carried out in sleeping chronic obstructive bronchitis (COB) patients (n-46).
(11) Alfalfa had no effect on rate of nontreated cob cell wall digestion, but increased (P less than .01) the rate for NH3-treated cobs.
(12) In trial 1, two qualities of alfalfa and smooth brome hays replaced 0, 15, 30 or 100% of an ammonia (NH3)-treated corn cob negative control diet in a digestion trial using 26 mixed breed wethers (31.8 kg).
(13) They were shown to be P22-cotransducible with a branch I cob marker at a mean frequency of 12%.
(14) No inhibition by EDTA was found in cob parenchyma tissue.
(15) Although both copies are identical in the 5' upstream region and through most of the coding region, only cob-1-specific mRNA is detected on RNA gel-blots.
(16) To elucidate the synthesis of cobalamin coenzymes in view of comparative biochemistry, tissue distribution of activity of aquacobalamin reductase [EC 1.6.99.8] catalyzing the reduction of hydroxocobalamin to cob(II)alamin was studied in some vertebrates.
(17) The solka floc and corn cob diets are acceptable for growing dairy heifers where a low mineral content is desired but normal growth rates need to be maintained.
(18) Xylan in such natural substrates as straw and corn-cobs was also subjected to enzymatic hydrolysis.
(19) Regions that hybridized to C. reinhardtii or wheat mitochondrial gene probes for subunit I of cytochrome oxidase (cox1), apocytochrome b (cob), three subunits of NADH dehydrogenase (nad1, nad2 and nad5) and the small and the large ribosomal RNAs (rrnS and rrnL, respectively) were localized on the C. moewusii mtDNA map by Southern blot analysis.
(20) A 13.1-kb DNA fragment carrying Pseudomonas denitrificans cob genes has been sequenced.
Dob
Definition:
Example Sentences:
(1) To evaluate the in vivo hemodynamics of smaller-sized (21 mm and 23 mm) Medtronic Hall (MH) valves in the aortic position, we measured the maximal pressure gradients (maxPG) at rest and during dobutamine (DOB) administration by continuous-wave Doppler echocardiography in 20 patients with aortic valve replacement.
(2) The second 12 cases were given the same doses of DOB instead of DOA.
(3) The most behaviorally potent analogues examined, DOB, DOM, and 5-methoxy-N,N-dimethyltryptamine, were found to possess rather high affirmities (pA2 = 7.35, 7.12, and 7.08, respectively) for the 5-HT receptors of the model system.
(4) [82Br]-DOB has been suggested as a potential brain scanning agent for nuclear medicine; 3b would have the advantage over DOB of providing the superior gamma-ray imaging properties of 131I or 123I.
(5) Potassium (K) values were almost constant during infusion of both drugs, but DOB reduced K concentration at the dose of 20 micrograms.kg-1.min-1.
(6) The results were as follows: 1) the effect of catecholamine on Ees prior to brain death was DA = DOB greater than NAD = AD.
(7) The study was aimed at comparing the effects of dobutamine (dob) and dopamine (dop) on isotonic contraction and rhythmicity of isolated guinea-pig papillary muscles (in oxygenated Tyrode at 37 degrees C), by taking into account: 1) the rate of stimulation (50% above the diastolic threshold) at 5 fixed periods: (RR: 1600, 1200, 1000, 800 and 400 ms); 2) 7 log concentrations (logC) of the index amine (from 10(-9) to 10(-3) M).
(8) Our results suggest that even in case of hypothermia, DOB retains a selective inotropic effect with no threat of arrhythmogenicity, and produces stable hemodynamics.
(9) Moreover, a significant correlation exists between drug potencies for (R)-(-)-[77Br]DOB-labeled sites and human hallucinogenic drug potencies (r = 0.89; p less than 0.01).
(10) People can also use their phones to dob in the neighbours.
(11) On the other hand, when CP and freqCP were coded, explanatory variables were AMP% and logAMP% (4.86 > t < 6.95, 0.06 > r2 < 0.09, p < 0.00001), but not the variable used to code the type of treatment (dob versus dop).
(12) In both systems, expression of this single serotonin receptor cDNA led to the appearance of both [3H]DOB and [3H]ketanserin binding sites with properties that matched their binding characteristics in mammalian brain homogenates.
(13) In competition experiments 8-OH-DPAT, TFMPP, mesulergine, DOB, and ICS 205-930 had low affinity for 3H-5HT-labeled 5HT1D sites, indicating that the pharmacology of the 5HT1D site is distinct from previously identified 5HT1A, 5HT1B, 5HT1C, 5HT2, and 5HT3 sites.
(14) Chronic DOB infusion was without effect on CRF concentrations in all hypothalamic and extrahypothalamic brain regions studied.
(15) This effect was apparently associated with down-regulation of the 5-HT2 receptor because high-affinity cortical [3H]DOB and hypothalamic (+-)-[125I]-1-(2,5-dimethoxy-4-iodophenyl)-2-amino-propane binding were decreased at this time as well.
(16) The effects of the 5-HT2-selective agonists 1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane (DOB) and 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on cat platelet aggregation were investigated and compared with those produced by serotonin (5-HT) and a positional isomer of DOB (i.e., isoDOB).
(17) (4) The Dob IgG is relatively resistant to digestion with papain and trypsin; however, it is readily digested with pepsin, although at an unusual site.
(18) In contrast, specific [3H]DOB binding cannot be detected in bovine cortical membranes.
(19) Classical serotonin antagonists, most of which are rather selective for 5-HT2 sites, and 5-HT2-selective antagonists are able to block the stimulus effects of DOM, DOB, and DOI, but not those of 8-OH DPAT or TFMPP.
(20) (3) The Dob heavy chain has three fewer residues of half-cystine than expected in gamma1 chains.