(1) Cobra collapsed into administration in 2009 after which Lord Bilimoria was criticised for using a “pre-pack” deal to buy back a stake in the firm.
(2) Phospholipase A2 from cobra venom (Naja naja naja) is a homogeneous, heat-stable enzyme that has a monomer molecular weight of only 11,000 and contains one histidine and one tryptophan residue.
(3) Most double-helical segments were reactive to cobra venom ribonuclease to some degree; the exceptions were the five "long-range" helices that are probably compactly folded within the structure.
(4) Only the enzyme from Naja naja naja (cobra) venom was found to be activated significantly by phosphorylcholine-containing compounds when hydrolyzing phosphatidylethanolamine.
(5) Sera depleted of terminal complement components by treatment with inulin or cobra venom factor and C8-deficient human serum did not support phagocytosis of the test strains.
(6) Cobra poly C9 that is resistant to reduction and boiling in SDS could also be demonstrated.
(7) (4) Proper vein-to-artery size ratio and "cobra-head" vein tailoring are desirable.
(8) Without injection of cobra venom factor, the organisms were eliminated rapidly from the lungs in the majority of mice, accompanied by a significant but transient decrease in the serum C3 level.
(9) The absence of chemical reactivities and cobra venom nuclease sensitivity in the terminal loops of helices 6 and 12 indicate a tertiary interaction unique to HeLa 18S rRNA.
(10) Water snakes (Natrix natrix), rat snakes (Ptyas korros), cobras (Naja naja), pythons (Python molurus), tortoises (Kachuga sp.
(11) Cobra plasma also lysed EAC1423 cells in presence of EDTA but not EAC142 cells (prepared with sheep erythrocytes, rabbit antibody, and human complement proteins) indicating the presence of C5 in cobra plasma that is susceptible to activation by the human C5 convertase.
(12) Adrenal gland is studied histologically in the common krait, the cobra and the viper.
(13) Venom entered the eyes of 9 patients spat at by the spitting cobra, Naja nigricollis.
(14) Enhanced cancer cell retention after cobra venom factor was not seen in mice deficient in complement component C5 and was diminished by pretreatment of animals with antineutrophil antibodies, catalase, inhibitors of lipoxygenase, thromboxane synthetase, and lipid peroxidation (oxygen radical scavenger).
(15) Complement depletion by prior treatment with cobra venom factor, caused a significant reduction of the thrombocytopenia, whereas DL-2-mercaptomethyl-3-guanidinoethylthiopropanoic acid, an inhibitor of carboxypeptidase N, potentiated the thrombocytopenia elicited by submaximal doses of either IgG aggregates or a homogeneous preparation of rat anaphylatoxin containing C5a.
(16) Cytolytic activity of cytotoxin isolated from the venom of the Indian cobra (Naja naja) on experimental tumor cells was far stronger than that on normal cells such as peritoneal exudate cells, spleen cells, and erythrocytes of the rat.
(17) The immunotoxin (IT) was prepared by conjugating cytotoxin from Chinese Cobra (Naja naja Atra) venom with monoclonal antibody (McAb) Wu71 directed to human T-cells.
(18) The make-up of the Cobra committee depends entirely on the nature of the issue, as the name refers to the location of the meeting, not a particular set of people.
(19) Only by depleting complement with cobra-venom factor could hamster xenograft survival be prolonged, and long-term survival was achieved by combining CsA with COF.
(20) We have previously described the irreversible inhibition of cobra venom phospholipase A2 (PLA2) by the marine natural product manoalide (MLD) (Lombardo, D., and Dennis, E. A.
Copperhead
Definition:
(n.) A poisonous American serpent (Ancistrodon conotortrix), closely allied to the rattlesnake, but without rattles; -- called also copper-belly, and red viper.
(n.) A nickname applied to a person in the Northern States who sympathized with the South during the Civil War.
Example Sentences:
(1) Of 39 rattlesnake (Crotalus and Sistrurus) bites, 20 patients received antivenin (53%), but of 23 copperhead and water moccasin (Agkistrodon) bites, only three patients (12.5%) received antivenin (p = 0.0025).
(2) Venoms from eastern and western diamondback and west coast Mexican rattlesnakes, Crotalus adamanteus, C. atrox and C. basiliscus basiliscus, respectively, and southern copperhead, Agkistrodon contortrix contortrix, were analyzed at the level of 1 mg of venom.
(3) From this experience, it appears that the majority of snake bites in children, especially copperhead bites, can be treated selectively and conservatively.
(4) Lymphocytic leukaemia was present in a broad banded copperhead and an Indian lion.
(5) The protein C activator detectable in the venom of the Southern Copperhead snake (Agkistrodon contortrix contortrix) was isolated by a combination of chromatofocusing on PBE-94 in the range pH9-7 and gel-filtration on Sephadex G-100 column.
(6) Procoagulant activity was present in certain isolated fractions of southern and broadbanded copperhead venoms, but was not apparent in the whole venoms.
(7) A direct acting fibrinolytic enzyme (fibrolase) has been isolated from venom of the southern copperhead snake (Agkistrodon contortrix contortrix).
(8) The protease from Southern Copperhead venom that activates protein C was purified to homogeneity by sulfopropyl (SP)-Sephadex C-50 ion-exchange chromatography, Sephadex G-150 gel filtration, and Mono-S fast protein liquid chromatography.
(9) A fibrinolytic enzyme present in Agkistrodon contortrix contortrix (southern copperhead) venom has been purified by combination of CM-cellulose chromatography, molecular sieve chromatography on Sephadex G-100, p-aminobenzamidine-agarose affinity chromatography, and DEAE-cellulose chromatography.
(10) We have used crotalase, a highly purified defibrinogenating serine proteinase from eastern diamondback rattlesnake venom and a fibrinolytic enzyme from southern copperhead venom to modulate selectively the tumor microenvironment in order to evaluate the role of fibrin(ogen) in tumor growth and dissemination.
(11) Using gel permeation chromatography with high performance liquid chromatograph (HPLC), a highly purified preparation of a protease has been obtained from the venom of the southern copperhead snake (Agkistrodon contortrix contortrix).
(12) The purified antibody reacted only with the fibrinolytic enzyme in southern copperhead venom as demonstrated by immunodiffusion and immunoelectrophoresis.
(13) These data demonstrate that the protein C activator from Southern Copperhead venom is a typical serine protease with a relatively broad specificity.
(14) Procoagulant activity was demonstrated in whole northern copperhead venom in the absence of exogenous calcium.
(15) Poisoning by members of the Crotalidae family (rattlesnakes, cotton-mouths [water moccasins] and copperheads) during pregnancy carries with it a fetal wastage rate of 43% and a maternal mortality rate of 10%.
(16) Amino-terminal sequence analysis revealed that the tropical moccasin protein C activator was highly homologous to the protein C activator isolated from Southern copperhead venom.
(17) Bites were inflicted by copperheads (56%), water moccasins (15%), and rattlesnakes (12%).
(18) Antiserum against bushmaster lectin cross-reacts with thrombolectin, cottonmouth lectin (CML), rattlesnake lectin (RSL), and copperhead lectin (CuHL) but not lectin from Jameson's mamba venom.
(19) The first step consists in the conversion of protein C in the test sample into activated protein C by means of an activator isolated from Southern Copperhead venom.
(20) Pit vipers (rattlesnakes, copperheads, cottonmouths, and massasaugas) are responsible for 99% of all snakebite poisonings; coral snakes and other foreign exotic species are responsible for the additional 1%.