(n.) A powerful alkaloid, C17H21NO4, obtained from the leaves of coca. It is a bitter, white, crystalline substance, and is remarkable for producing local insensibility to pain.
Example Sentences:
(1) Altogether, 29% of the drivers had evidence of alcohol, marijuana, cocaine, prescription or nonprescription stimulants, or some combination of these, in either blood or urine.
(2) Mechanisms of drug toxicity, i.e., vascular pathology demonstrated from chronic use of cocaine.
(3) With chronic cocaine use, neurotransmitter and neuroendocrine alterations occur.
(4) In pentobarbital-anesthetized rats or in perfused hind paw of rats, the potentiation induced by cocaine and tripelennamine was more marked to norepinephrine than to epinephrine, but an inverse relation between norepinephrine and epinephrine was observed in the potentiation by I and II.
(5) The disposition of radiolabeled cocaine in humans has been studied after three routes of administration: iv injection, nasal insufflation (ni, snorting), and smoke inhalation (si).
(6) When S+ followed cocaine, stereotyped bar-pressing developed with markedly increased responding during the remainder of the session.
(7) The effects were atropine-resistant and qualitatively similar to those seen with cocaine.
(8) Knowing the risks of transporting cocaine from Africa to the US, and given the slim profit margin, “tell me who will be doing that kind of deal?” Chigbo asked.
(9) Cocaine produces simple hallucinations, PCP can produce complex hallucinations analogous to a paranoid psychosis, while LSD produces a combination of hallucinations, pseudohallucinations and illusions.
(10) Inhibition of DNA synthesis by cocaine in developing brain was not secondary to ischemia, nor to local anesthesia, as alpha-adrenergic blockade with phenoxybenzamine afforded no protection, and lidocaine could not substitute for cocaine.
(11) Cocaine, 3 microM, shifted the noradrenaline concentration response curve to the left about 0.4 log units in all renal vessel groups, thus renal vascular smooth muscle sensitivity to noradrenaline was significantly greater in vessels from rats receiving CyA than in vessels from control rats.
(12) Similarities and differences in the sensitization induced by cocaine and amphetamine (which are though to have different mechanisms of actions although common behavioral outcomes) have not been thoroughly studied.
(13) However, they do indicate that cocaine is only a weak aversion-inducing agent.
(14) Driving-under-the-influence (DUI) offenders with either alcohol- or cocaine-related problems were studied.
(15) The cardiac risk of cocaine body packing was studied by means of continuous ECG monitoring in 13 cocaine body-packers during spontaneous elimination.
(16) We present a 16-year-old with chest pain temporally related to cocaine use and discuss the relationship between cocaine use and acute myocardial infarction that has been seen in the adult population.
(17) Both acute and chronic cocaine treatments significantly increased plasma concentrations of corticosterone and reduced the ratios of 3,4-dihydroxyphenylacetic acid to dopamine and 5-hydroxyindoleacetic acid to serotonin in several brain regions.
(18) Daily cocaine injection into rodents produces a progressive increase in the motor stimulant effect of acute cocaine administration.
(19) The nine cocaine users, when compared with 14 insulin-dependent diabetics on dialysis matched by protocol, were found to be similar in terms of diabetic retinopathy and metabolic neuropathy.
(20) In view of recent reports demonstrating that illicit cocaine use may cause rhabdomyolysis, we reviewed the collective experience of a university-affiliated medical center to identify patients with cocaine-induced rhabdomyolysis.
Coke
Definition:
(n.) Mineral coal charred, or depriver of its bitumen, sulphur, or other volatile matter by roasting in a kiln or oven, or by distillation, as in gas works. It is lagerly used where / smokeless fire is required.
(v. t.) To convert into coke.
Example Sentences:
(1) An actor dressed like one of the polar bears that figure in Coke ads limped up, wearing a prosthesis on one paw, a dialysis bag and tubing.
(2) The risk for gastric cancer and non-malignant respiratory disease among the workers of the coke shipping department was increased but the SMRs did not reach statistical significance.
(3) The coke sailed up my nasal passage, leaving behind the delicious smell of a hot leather car seat on the way back from the beach.
(4) And failing that, drink a Diet Coke and a beer simultaneously just before you go in.
(5) A video obtained by the Mail on Sunday showing Flowers counting out £300 after being asked for "money for the coke" also sparked calls by Conservative MP Andrew Tyrie for the current system of authorising top bankers to be overhauled.
(6) Thirty years after one of the pivotal clashes in the miners' strike of 1984 when violent confrontations erupted at the Orgreave coking plant, the area outside Sheffield could barely look more different.
(7) The environmentally exposed donors were residents from the vicinity of a coke factory; the occupationally exposed persons were cokery workers, while rural region inhabitants served as a control group.
(8) Last month one woman asked for a bag of crisps and a bottle of cherry coke and burst into tears when she got it.
(9) And while we're thinking of breaking things, check out an Italian's attempt on a world record involving a bottle of coke, some Nutella chocolate spread, some Mentos and a condom.
(10) Also, coke oven workers had slightly higher adduct values than age, sex and smoking matched controls.
(11) Approximate relative risks, which take into account race, age, and calendar years of follow-up, have been calculated for various work areas of the coke plant.
(12) Thiocyanate-assimilatig bacterium, TK 21, was isolated from activated sludge used for the treatment of thiocyanate contained in coke-oven liquor.
(13) Six normal subjects each ingested a single 12-oz can of a diet cola (Diet Coke) providing 184 mg aspartame (APM), of which 104 mg is phenylalanine (Phe), and, on another occasion, a single 12-oz can of regular cola (Coke Classic).
(14) Fuelled by latent ambition (and maybe a bit of that coke), Joan – with the help of some divine Cosgrovian intervention – decided she could turn her hand to producing ads.
(15) The purpose of this study was to determine the clinical, epidemiological and evolutive characteristics of interdigital and plantar intertrigo of the feet among people working in a coking plant, a potash mine and a motorcar factory.
(16) Inoculation of different trypanosome strains into volunteers yielded positive parasitaemia for original isolates from lion, hyaena, and Coke's hartebeest.
(17) The effect is of someone with a boyish energy who has had too many Cokes, but even on bad days, says Fox, "I don't care.
(18) Not only that, it’s allowed other newspapers to declare open season on Cameron’s private life, as we see from today’s “coke parties” splash in the Sun .
(19) However, Innocent was one of the brands highlighted last year as containing high levels of sugar: a 250ml serving of its pomegranate, blueberry and acai smoothie contains 34g of sugar, around the same as a 330ml can of Coke.
(20) And, though I mixed heroin and coke [Goldin continued to use heroin but not intravenously], I never smoked crack.