(n.) A powerful alkaloid, C17H21NO4, obtained from the leaves of coca. It is a bitter, white, crystalline substance, and is remarkable for producing local insensibility to pain.
Example Sentences:
(1) Altogether, 29% of the drivers had evidence of alcohol, marijuana, cocaine, prescription or nonprescription stimulants, or some combination of these, in either blood or urine.
(2) Mechanisms of drug toxicity, i.e., vascular pathology demonstrated from chronic use of cocaine.
(3) With chronic cocaine use, neurotransmitter and neuroendocrine alterations occur.
(4) In pentobarbital-anesthetized rats or in perfused hind paw of rats, the potentiation induced by cocaine and tripelennamine was more marked to norepinephrine than to epinephrine, but an inverse relation between norepinephrine and epinephrine was observed in the potentiation by I and II.
(5) The disposition of radiolabeled cocaine in humans has been studied after three routes of administration: iv injection, nasal insufflation (ni, snorting), and smoke inhalation (si).
(6) When S+ followed cocaine, stereotyped bar-pressing developed with markedly increased responding during the remainder of the session.
(7) The effects were atropine-resistant and qualitatively similar to those seen with cocaine.
(8) Knowing the risks of transporting cocaine from Africa to the US, and given the slim profit margin, “tell me who will be doing that kind of deal?” Chigbo asked.
(9) Cocaine produces simple hallucinations, PCP can produce complex hallucinations analogous to a paranoid psychosis, while LSD produces a combination of hallucinations, pseudohallucinations and illusions.
(10) Inhibition of DNA synthesis by cocaine in developing brain was not secondary to ischemia, nor to local anesthesia, as alpha-adrenergic blockade with phenoxybenzamine afforded no protection, and lidocaine could not substitute for cocaine.
(11) Cocaine, 3 microM, shifted the noradrenaline concentration response curve to the left about 0.4 log units in all renal vessel groups, thus renal vascular smooth muscle sensitivity to noradrenaline was significantly greater in vessels from rats receiving CyA than in vessels from control rats.
(12) Similarities and differences in the sensitization induced by cocaine and amphetamine (which are though to have different mechanisms of actions although common behavioral outcomes) have not been thoroughly studied.
(13) However, they do indicate that cocaine is only a weak aversion-inducing agent.
(14) Driving-under-the-influence (DUI) offenders with either alcohol- or cocaine-related problems were studied.
(15) The cardiac risk of cocaine body packing was studied by means of continuous ECG monitoring in 13 cocaine body-packers during spontaneous elimination.
(16) We present a 16-year-old with chest pain temporally related to cocaine use and discuss the relationship between cocaine use and acute myocardial infarction that has been seen in the adult population.
(17) Both acute and chronic cocaine treatments significantly increased plasma concentrations of corticosterone and reduced the ratios of 3,4-dihydroxyphenylacetic acid to dopamine and 5-hydroxyindoleacetic acid to serotonin in several brain regions.
(18) Daily cocaine injection into rodents produces a progressive increase in the motor stimulant effect of acute cocaine administration.
(19) The nine cocaine users, when compared with 14 insulin-dependent diabetics on dialysis matched by protocol, were found to be similar in terms of diabetic retinopathy and metabolic neuropathy.
(20) In view of recent reports demonstrating that illicit cocaine use may cause rhabdomyolysis, we reviewed the collective experience of a university-affiliated medical center to identify patients with cocaine-induced rhabdomyolysis.
Snow
Definition:
(n.) A square-rigged vessel, differing from a brig only in that she has a trysail mast close abaft the mainmast, on which a large trysail is hoisted.
(n.) Watery particles congealed into white or transparent crystals or flakes in the air, and falling to the earth, exhibiting a great variety of very beautiful and perfect forms.
(n.) Fig.: Something white like snow, as the white color (argent) in heraldry; something which falls in, or as in, flakes.
(v. i.) To fall in or as snow; -- chiefly used impersonally; as, it snows; it snowed yesterday.
(v. t.) To scatter like snow; to cover with, or as with, snow.
Example Sentences:
(1) And this is the supply of 30% of the state’s fresh water.” To conduct the survey, the state’s water agency dispatches researchers to measure the level of snow manually at 250 separate sites in the Sierra Nevada, Rizzardo said.
(2) While they may always be encumbered by censorship in a way that HBO is not, the success of darker storylines, antiheroes and the occasional snow zombie will not be lost in an entertainment industry desperate to maintain its share of the audience.
(3) Children as young as 18 months start by sliding on tiny skis in soft supple boots, while over-threes have more formal lessons in the snow playground.
(4) The fairytales – which have been distributed by leaflet to universities around Singapore – include versions of Cinderella, the Three Little Pigs, Rapunzel and Snow White, each involving a reworked tale that relates to fertility, sex or marriage, and a resulting moral.
(5) The world's greatest snow-capped peaks, which run in a chain from the Himalayas to Tian Shan on the border of China and Kyrgyzstan, have lost no ice over the last decade, new research shows.
(6) And there is plenty of beauty in London - seeing Parliament Square in the snow, the dome of St Paul's rising above the City, the simple perfection of a Georgian terrace or the quietly elegant streets of Mayfair.
(7) Faster than ever we could deal with them these shattered men were coming in, and yet across the few acres of snow before me the busy guns were making more.
(8) The only people we saw was a small party on snow shoes.
(9) As the level of disruption across the country continued to escalate, the government ordered an urgent audit of the country's snow readiness .
(10) Daily subcutaneous injection of L-dopa for 4 weeks into 2-year-old low egg production hens resulted in a lightening of feather color to snow white and increased oviduct and ovary weights and the development of well developed follicles.
(11) "And I think that there was some major journalist [the Channel Four news presenter Jon Snow in 2010] who would be as big a supporter of Remembrance Day as anybody, but who said he didn't wear a poppy because he felt people were telling him he should do it.
(12) As Florian Grimm, the local head of snow management, told a colleague recently: “Today nobody would accept stones any more, or spots of grass in spring.
(13) It was minus five degrees and snowing on the day we fitted him.
(14) As night fell, one teenager, Alex, who had slipped out of an independent school (she refused to say which one) was heading home, pausing only grab a flier advertising a "Snow Rave" for 16-18-year-olds.
(15) Facebook Twitter Pinterest View over the snow fields and lake.
(16) He added the rainfall could turn to snow in parts of Scotland.
(17) The original 1858 edition of John Snow's On Chloroform and Other Anaesthetics, from which came the Wood Library-Museum of Anesthesiology reprints in 1971 and 1989, was donated to the Wood Library-Museum by Ralph Waters of Madison, Wisconsin, in 1967.
(18) Then they trudged through heavy, deep snow and climbed up to another ridge.
(19) The early appearance of the stable snow cover facilitates a rapid drop in the number of NFRS cases as early as in October, while prolonged autumn with rains, snow, periods of thaw and ice-covered ground leads to a rise in NFRS morbidity occurring in autumn and winter and ending only in March.
(20) There's even a little used term for it – rasputitsa – a biannual phenomenon that appears in spring because of melting snow and in the autumn because of rain.