(n.) An appendage of the labyrinth of the internal ear, which is elongated and coiled into a spiral in mammals. See Ear.
Example Sentences:
(1) In addition to the aqueduct other associated inner ear anomalies have been identified in 60% of this population including: enlarged vestibule (14); enlarged vestibule and lateral semicircular canal (7); enlarged vestibule and hypoplastic cochlea (4); and hypoplastic cochlea (4).
(2) We tested the hypothesis that furosemide interferes with energy generation in the cochlea, and determined its effect on CO2 formation from glucose and glyceroaldehyde-3-phosphate dehydrogenase (GAPDH) activity by examining biochemical and histochemical changes in the cochlea, the kidney, and the liver.
(3) Although sound pressure levels are high, they are probably reduced before reaching the cochlea of the fetus because of the surrounding amniotic fluid and the fluid in the middle ear.
(4) We use this procedure to assess the excitability of the auditory nerve, the patency of the cochlea and to detect undesirable side effects of electrical stimulation, such as facial nerve activation.
(5) After 2-4 days the cochleas were prepared for morphological analysis by scanning electron microscopy and chemical analysis by X-ray dispersive microanalysis.
(6) Complete atrophy of variable lengths of the terminal basal coil cells was also found in all elderly cochleas.
(7) In a series with sixteen normal adult volunteers, 22 to 45 years in age, 100% of the cochleae, vestibules, and lateral and posterior semicircular canals were clearly demonstrated in T2 weighted images.
(8) In animals receiving passive (unstimulated) implants, morphometric analysis of spiral ganglion cell density showed no significant difference in ganglion cell survival between the implanted cochleas and the contralateral control ears.
(9) Measurements were obtained from fibers innervating hair cells in both the region of the cochlea that contains a tectorial membrane (tectorial fibers) and the region where hair-cell stereocilia are free-standing in scala media (free-standing fibers).
(10) Histologically, no discernible changes in the hair cells or sensory hairs were found with a scanning electron microscope at about 6 hours after 10 krad irradiation, while with a transmission electron microscope, the outer hair cells in the basal coil of the cochlea were found to be mostly destroyed.
(11) A combined morphological and physiological study on the effect of saccus obliteration on the cochlea and the vestibular labyrinth of the rat is presented.
(12) It is suggested that in a programme designed to implant such children at 2 years of age, techniques should be chosen that neither damage the cochlea nor the middle ear sound conducting mechanism.
(13) Blood flow in the cochlea, vestibular apparatus and facial nerve was investigated in the 12 temporal bones of 6 guinea pigs using non-radioactive microspheres.
(14) The total length in mm of each cochlea was also measured (Length).
(15) We have made whole-cell, tight-seal recordings from short (outer) hair cells isolated from the chick's cochlea.
(16) Morphological evidence suggests that the membrane participates in: (a) the release of mechanical energy supplied by the ossicular chain to the labyrinthine fluids; (b) an alternative route for sound energy to enter the cochlea; (c) secretion into and absorption from perilymph; and (d) the defense system of the middle and inner ears.
(17) Human cochleae were fixed in glutaraldehyde, without the use of osmium.
(18) The findings are discussed in relation to changes in nerve conduction speed and hearing loss; a possible correlation between the fiber diameter distribution and the tonotopical arrangement of the cochlea is suggested.
(19) Histological examination of the cochleas of monkeys with permanent hearing losses revealed corresponding damage to the high-frequency region of the organ of Corti.
(20) The endo- and perilymphatic glycocalyx of the cochlear epithelia were investigated ultrastructurally in normal and hydropic cochleas using the electron-dense markers cationized ferritin and colloidal thorium.
Cochlear
Definition:
(a.) Of or pertaining to the cochlea.
Example Sentences:
(1) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
(2) Furthermore the limit between hearing aid fitting an cochlear implantation is discussed.
(3) The lengths and heights of the scalae tympani in ten pairs of serially sectioned temporal bones were measured by an adaptation of the serial section method of cochlear reconstruction.
(4) Neither light nor electron microscopy revealed significant morphologic alterations in the cochlear elements of the exposed offspring.
(5) The next implanted device will have: a. constant current; b. programming of a particular current value for each electrode; and c. stimulation of the cochlear nerve through an extra cochlear electrode bearer, allowing deep implantation without deafness.
(6) There is evidence to indicate that these losses are due to congenital ossicular anomalies, eustachian tube dysfunction from craniofacial malformation, and cochlear involvement that is greatest for high frequencies.
(7) At the House Ear Institute, speech and language assessments are a regular part of the evaluation protocol for the cochlear implant clinical trials in children.
(8) Patterns of degeneration of cochlear hair cells were compared with the functional audiometric examinations.
(9) These results are consistent with changes in cochlear metabolism which have been reported previously using similar techniques, suggesting that increases in blood flow may be linked to increases in local metabolism.
(10) Measurements of volume and length were made on isolated guinea pig cochlear outer hair cells (OHCs) in an attempt to establish whether OHC shortening was accompanied by changes in cell volume.
(11) We have mapped cochlear nerve terminations in the cochlear nucleus with DiI and, using three-dimensional reconstructions, have demonstrated the topography and geometry of the cochlear input.
(12) A mathematical model of cochlear processing is developed to account for the nonlinear dependence of frequency selectivity on intensity in inner hair cell and auditory nerve fiber responses.
(13) Primary cochlear afferents are found only in the ventral zone of the dorsal cochlear nucleus.
(14) Phaseolus vulgaris leucoagglutinin (PHA-L), a kidney bean lectin used as an anterograde tracer, was iontophoretically injected into the posteroventral cochlear nucleus (PVCN) of guinea pigs.
(15) Other differences in cytoarchitecture, within the great apes and humans, include decreases in the small and giant cell populations of the cochlear complex.
(16) The shapes of interval histograms agreed with those found in cat cochlear nerve fibres.
(17) The operative manipulations representing stretch or compression injury to the cochlear nerve in the CPA leads to an acute traumatic cranial nerve root lesion--a retrocochlear lesion.
(18) The effects of auditory fatigue, using a temporary threshold shift (TTS) paradigm, on cochlear microphonics (CM) and on auditory brainstem-evoked potentials (ABEP), were studied in normal-hearing subjects during the development of permanent threshold shift (PTS).
(19) The magnitude of these changes correlated well with the intrinsic ototoxicity of the drugs previously established in cochlear perfusions: neomycin greater than gentamicin approximately equal to tobramycin greater than amikacin approximately equal to kanamycin approximately equal to netilmicin greater than neamine approximately equal to spectinomycin.
(20) So far we believe that loss of hearing caused during these operations is mainly due to the unfavorable location of the cochlear blood supply through the meatus.