What's the difference between cochlea and modiolus?
Cochlea
Definition:
(n.) An appendage of the labyrinth of the internal ear, which is elongated and coiled into a spiral in mammals. See Ear.
Example Sentences:
(1) In addition to the aqueduct other associated inner ear anomalies have been identified in 60% of this population including: enlarged vestibule (14); enlarged vestibule and lateral semicircular canal (7); enlarged vestibule and hypoplastic cochlea (4); and hypoplastic cochlea (4).
(2) We tested the hypothesis that furosemide interferes with energy generation in the cochlea, and determined its effect on CO2 formation from glucose and glyceroaldehyde-3-phosphate dehydrogenase (GAPDH) activity by examining biochemical and histochemical changes in the cochlea, the kidney, and the liver.
(3) Although sound pressure levels are high, they are probably reduced before reaching the cochlea of the fetus because of the surrounding amniotic fluid and the fluid in the middle ear.
(4) We use this procedure to assess the excitability of the auditory nerve, the patency of the cochlea and to detect undesirable side effects of electrical stimulation, such as facial nerve activation.
(5) After 2-4 days the cochleas were prepared for morphological analysis by scanning electron microscopy and chemical analysis by X-ray dispersive microanalysis.
(6) Complete atrophy of variable lengths of the terminal basal coil cells was also found in all elderly cochleas.
(7) In a series with sixteen normal adult volunteers, 22 to 45 years in age, 100% of the cochleae, vestibules, and lateral and posterior semicircular canals were clearly demonstrated in T2 weighted images.
(8) In animals receiving passive (unstimulated) implants, morphometric analysis of spiral ganglion cell density showed no significant difference in ganglion cell survival between the implanted cochleas and the contralateral control ears.
(9) Measurements were obtained from fibers innervating hair cells in both the region of the cochlea that contains a tectorial membrane (tectorial fibers) and the region where hair-cell stereocilia are free-standing in scala media (free-standing fibers).
(10) Histologically, no discernible changes in the hair cells or sensory hairs were found with a scanning electron microscope at about 6 hours after 10 krad irradiation, while with a transmission electron microscope, the outer hair cells in the basal coil of the cochlea were found to be mostly destroyed.
(11) A combined morphological and physiological study on the effect of saccus obliteration on the cochlea and the vestibular labyrinth of the rat is presented.
(12) It is suggested that in a programme designed to implant such children at 2 years of age, techniques should be chosen that neither damage the cochlea nor the middle ear sound conducting mechanism.
(13) Blood flow in the cochlea, vestibular apparatus and facial nerve was investigated in the 12 temporal bones of 6 guinea pigs using non-radioactive microspheres.
(14) The total length in mm of each cochlea was also measured (Length).
(15) We have made whole-cell, tight-seal recordings from short (outer) hair cells isolated from the chick's cochlea.
(16) Morphological evidence suggests that the membrane participates in: (a) the release of mechanical energy supplied by the ossicular chain to the labyrinthine fluids; (b) an alternative route for sound energy to enter the cochlea; (c) secretion into and absorption from perilymph; and (d) the defense system of the middle and inner ears.
(17) Human cochleae were fixed in glutaraldehyde, without the use of osmium.
(18) The findings are discussed in relation to changes in nerve conduction speed and hearing loss; a possible correlation between the fiber diameter distribution and the tonotopical arrangement of the cochlea is suggested.
(19) Histological examination of the cochleas of monkeys with permanent hearing losses revealed corresponding damage to the high-frequency region of the organ of Corti.
(20) The endo- and perilymphatic glycocalyx of the cochlear epithelia were investigated ultrastructurally in normal and hydropic cochleas using the electron-dense markers cationized ferritin and colloidal thorium.
Modiolus
Definition:
(n.) The central column in the osseous cochlea of the ear.
Example Sentences:
(1) The electrodes can be implanted in bundles through the round window or into the modiolus; they can, however, also be introduced individually through several drill holes in the promontory for placement in the scala tympani and vestibuli.
(2) The peripheral and central axons also degenerated, and the losses of both the radial nerve fibers in the osseous spiral lamina and the central axons passing into the modiolus displayed selective topographies that paralleled the cell loss within the spiral ganglion.
(3) In the developing cochlear nerve, a central tissue projection is present before birth, but regresses somewhat before a marked outgrowth of central nervous tissue along the nerve takes place, which reaches into the modiolus during the first week postnatum.
(4) A trough around the modiolus was drilled, and the electrode array was placed in it.
(5) The function of the vessel loops in the modiolus is to flatten the pulse wave as well as to regulate the blood flow in the microvascular bed by vasomotion.
(6) The cochlea was dissected into three parts: organ of Corti + modiolus (OC + M), lateral wall (LW), and cochlear nerve (CN), and then PG's formed by these tissues were determined after a 5-min incubation of the homogenates.
(7) Implantation involved creation of a channel for the electrode to wrap around the modiolus.
(8) Each unit begins with special blood vessel convoluts in the modiolus, consisting of loops of arterioles.
(9) The openings in the bone on the scala vestibuli and tympani sides of the modiolus are considered to be communication routes for the transport of fluids from the perineural and perivascular spaces in the modiolus to the perilymph in the scalae.
(10) In cryostat sections, tyrosine hydroxylase and dopamine beta-hydroxylase-like immunoreactivities fibers were seen in the modiolus that did not extend to the organ of Corti.
(11) A vessel, formed by the confluence of the vascular network on the modiolar wall and having a spiral course into the internal auditory meatus was found in the modiolus of the basal turn.
(12) HRP permeated interendothelial spaces lining the modiolus to reach the scala vestibuli lymphatics close to all the above areas were also permeated by HRP, but the inner tunnel was devoid of the marker.
(13) Multiple anomalies include: abnormal narrowing of the crus commune-utricle junction, superiorly located crus commune and posterior semicircular canal, underdeveloped modiolus, absence of the bony septum between the middle and apical coil (existence of scala communis in left ear), abnormally small internal auditory meatus, and abnormal direction of internal auditory canal, large cartilaginous mass around the superior semicircular canal and in the tympanic end of the fissula ante fenestram, small facial nerve, large facial bony canal dehiscence, anomalic stapes, etc.
(14) These scanning electron microscopic findings were confirmable by serial sections of the dural veins in the internal auditory meatus and the modiolus.
(15) Preliminary studies have shown that the nerve will survive the placement of electrodes both into the modiolus and the scala tympani.
(16) Some accumulation of lidocaine was found in the modiolus, but almost none in the stria vascularis.
(17) These regenerating cochlear nerve fibers were found in the osseous spiral lamina, modiolus and internal auditory meatus, but these fibers atrophied and disappeared afterward.
(18) However, detailed information concerning the vasculature of the modiolus is still unavailable, and even the existence of venous drainage through the internal auditory meatus is not agreed upon.
(19) The modiolus on the scala vestibuli side had a canal for the spiral modiolar artery.
(20) The spiral ganglion dendrites within the osseous spiral lamina of the basal turn project radially, nearly perpendicular to the central axis of the modiolus.