What's the difference between codeine and coneine?
Codeine
Definition:
(n.) One of the opium alkaloids; a white crystalline substance, C18H21NO3, similar to and regarded as a derivative of morphine, but much feebler in its action; -- called also codeia.
Example Sentences:
(1) No associations were found between sex, body-weight, smoking habits, age, urine volume or urine pH and the O-demethylation of codeine.
(2) The analgesic effects of acetaminophen alone were not significantly different from acetaminophen in combination with codeine.
(3) These results have implications in utilizing codeine phosphate as a positive skin prick test control for allergy testing.
(4) In the degradation reaction, formation of the symmetrically substituted citrate ester of codeine, 1, was found to predominate.
(5) Analysis of hair samples obtained from 10 drug-free control subjects were negative for 6-acetylmorphine, morphine, and codeine.
(6) Codeine and fenoprofen rapidly achieve their ultimate plasma equilibrium levels (on a q.
(7) Codeine 60 mg was significantly superior to placebo in all pain measures.
(8) Based on the current understanding that the analgesic effect of codeine is mediated primarily through morphine, one might anticipate that poor metabolisers would not obtain pain relief from codeine.
(9) One hundred patients completed the study and were randomly assigned to four treatment groups, each receiving either functioning transcutaneous electrical nerve stimulators (TENS), placebo TENS, acetaminophen with codeine and a functioning TENS, or acetaminophen with codeine and a placebo TENS.
(10) Codeine was converted to codeinone and 14-hydroxycodeinone.
(11) These data suggest that codeine undergoes filtration at the glomerulus, tubular secretion and passive reabsorption.
(12) The animals completely generalized to the effects of codeine, fentanyl and EK-209, but did not generalize completely to the effect of ethylketocyclazocine.
(13) Haloperidol, used in a dose which did not affect the locomotor activity of mice, completely blocked or even reversed the stimulatory action of morphine and fentanyl, and potentiated the depression of locomotor activity produced by pentazocine and codeine.
(14) Comparison of the area under the time-effect curves for the combination and the individual components confirmed the synergism between codeine and paracetamol.
(15) The hydrolysis of codeine-6-glucuronide by beta-glucuronidase was incomplete and urine reduced the extent of hydrolysis.
(16) After amphetamine, codeine, or ampicillin administration, no target organ toxicity was seen in rats or mice, even at doses which caused body weight gain depression.
(17) Codeine 60 mg had a more rapid onset of action and greater maximal effects than Ro 15-8081.
(18) Protection by codeine 20 mg, dextromethorphan 30 mg, noscapine 30 mg, and placebo against citric acid-induced cough was determined in eighteen healthy subjects.
(19) The clinical significance of this polymorphism to the antidiarrhoeal and antitussive properties of codeine is not known.
(20) These data suggest that codeine-6-glucuronide undergoes filtration at the glomerulus and tubular reabsorption.