(n.) One of the opium alkaloids; a white crystalline substance, C18H21NO3, similar to and regarded as a derivative of morphine, but much feebler in its action; -- called also codeia.
Example Sentences:
(1) No associations were found between sex, body-weight, smoking habits, age, urine volume or urine pH and the O-demethylation of codeine.
(2) The analgesic effects of acetaminophen alone were not significantly different from acetaminophen in combination with codeine.
(3) These results have implications in utilizing codeine phosphate as a positive skin prick test control for allergy testing.
(4) In the degradation reaction, formation of the symmetrically substituted citrate ester of codeine, 1, was found to predominate.
(5) Analysis of hair samples obtained from 10 drug-free control subjects were negative for 6-acetylmorphine, morphine, and codeine.
(6) Codeine and fenoprofen rapidly achieve their ultimate plasma equilibrium levels (on a q.
(7) Codeine 60 mg was significantly superior to placebo in all pain measures.
(8) Based on the current understanding that the analgesic effect of codeine is mediated primarily through morphine, one might anticipate that poor metabolisers would not obtain pain relief from codeine.
(9) One hundred patients completed the study and were randomly assigned to four treatment groups, each receiving either functioning transcutaneous electrical nerve stimulators (TENS), placebo TENS, acetaminophen with codeine and a functioning TENS, or acetaminophen with codeine and a placebo TENS.
(10) Codeine was converted to codeinone and 14-hydroxycodeinone.
(11) These data suggest that codeine undergoes filtration at the glomerulus, tubular secretion and passive reabsorption.
(12) The animals completely generalized to the effects of codeine, fentanyl and EK-209, but did not generalize completely to the effect of ethylketocyclazocine.
(13) Haloperidol, used in a dose which did not affect the locomotor activity of mice, completely blocked or even reversed the stimulatory action of morphine and fentanyl, and potentiated the depression of locomotor activity produced by pentazocine and codeine.
(14) Comparison of the area under the time-effect curves for the combination and the individual components confirmed the synergism between codeine and paracetamol.
(15) The hydrolysis of codeine-6-glucuronide by beta-glucuronidase was incomplete and urine reduced the extent of hydrolysis.
(16) After amphetamine, codeine, or ampicillin administration, no target organ toxicity was seen in rats or mice, even at doses which caused body weight gain depression.
(17) Codeine 60 mg had a more rapid onset of action and greater maximal effects than Ro 15-8081.
(18) Protection by codeine 20 mg, dextromethorphan 30 mg, noscapine 30 mg, and placebo against citric acid-induced cough was determined in eighteen healthy subjects.
(19) The clinical significance of this polymorphism to the antidiarrhoeal and antitussive properties of codeine is not known.
(20) These data suggest that codeine-6-glucuronide undergoes filtration at the glomerulus and tubular reabsorption.
Opium
Definition:
(n.) The inspissated juice of the Papaver somniferum, or white poppy.
Example Sentences:
(1) The only entirely original stage work from this period was the spectacular one-man show Needles And Opium in 1991, which intermingled stories of love and addiction from the lives of Jean Cocteau and Miles Davis with an account of the meltdown of one of Lepage's own long-term relationships.
(2) Social changes going on in the society were reflected in choice of substance forms by younger people as compared to their elders (e.g., cigarettes vs pipes or cigars, heroin vs opium, manufactured vs village-produced alcohol).
(3) American frustrations burst into the open in October 2009 when serving and retired officials told the New York Times Karzai was a key player in Afghanistan's illegal opium trade, which helps fund the Taliban insurgency, while on the CIA payroll.
(4) A transformation of the corrupt economy could take up to two decades, and opium production is likely to climb beyond 2013's worrying levels before it falls again, said Jean-Luc Lemahieu, outgoing head of the UN office on drugs and crime in Afghanistan .
(5) Athletic elitism, the glorification of the human body, has succeeded religion as Marx's opium of the people.
(6) Cannabis and opium use has been in Nepal for centuries and in the past they did not pose much of a problem.
(7) In Henley, he encountered with interest the bookshop-owning lesbians who had taken opium with Cocteau, and a prim, elderly lady who had, in her youth, urinated regularly upon pioneering sexologist Havelock Ellis.
(8) But the ACMD research clearly found that the majority of people were not “parked” on opium substitution treatment for long periods of time, with only 10-15% receiving treatment for more than five years.
(9) With lots of water and fertile land, Sangin is perfect for growing the poppies currently being harvested for their opium sap.
(10) Subjects with a positive family history of opium use had an earlier age of onset than the subjects without a family history of opium use.
(11) Two ethnic groups in Laos were compared: the Hmong (or Meo), a tribal group with access to opium in their homes; and the Lao, a peasant people with more limited access, usually in opium dens.
(12) The time-course of changes in vegetative tests was studied in 47 men suffering from stage II opium dependence.
(13) Fifty-six addicted "world travelers" were studied at a treatment facility for opium addicts in Laos.
(14) Cash crops have diversified and replaced the former opium fields; the economy is moving away from a subsistence and cash economy to a mostly cash economy.
(15) They may well also be driving the Taliban effort in Helmand, since control of the opium-rich province would hand a major political advantage to whichever leader achieved it.
(16) Naltrexone blocked opioid-induced euphoria and decreased the craving for opium, but it did not inhibit drug usage.
(17) These studies contribute to the evidence that different cytochrome P-450-dependent mono-oxygenase systems are involved in the O- and N-dealkylation of opium alkaloids.
(18) Opium poppy latex contains a group of laticifer-specific, low-molecular-weight polypeptides called major latex proteins (MLPs).
(19) Communities raising opium poppy as a cash crop had highest crude rates of addiction (7.0-9.8 addicts per 100 people).
(20) The British prosecuted two opium wars in the cause of freedom to export and sell the produce of the East India Company's Bengal factories.