(a.) Allied by blood; kindred by birth; specifically (Law), related on the mother's side.
(a.) Of the same or a similar nature; of the same family; proceeding from the same stock or root; allied; kindred; as, a cognate language.
(n.) One who is related to another on the female side.
(n.) One of a number of things allied in origin or nature; as, certain letters are cognates.
Example Sentences:
(1) The use of sigma 54 promoters, known to require cognate binding proteins, could allow the fine-tuning that provides the temporal ordering of flagellar gene transcription.
(2) To date, a cognate action of E2 on the GnRH pulse generator has not been described.
(3) Cognate sites in genomes that diverged approximately 100 million years ago can be detected by PCR assays based on primer pairs from unique sequences.
(4) Cognate heat shock proteins might be involved in this renaturation process.
(5) LEW rats immunized with each of the three DA MHC chains produced alloantibodies to these chains, suggesting that indirect allorecognition did occur, because of the requirement for cognate recognition of B cells by T helper cells.
(6) Microcultures of helper T (Th) cells and a few appropriately primed murine B cells can be used to detect cognate T-B interactions which lead to clonal production of IgM, IgG1, and IgE.
(7) We have investigated the structural relationship of heat-inducible and cognate members of the human hsp70 gene family.
(8) If protein mixtures are subjected to affinity elution the cognate pair [tRNAPhe-phenylalanyl-tRNA synthetase] is eluted first, followed by noncognate pairs.
(9) These results suggest that cognate T-B cell interactions may be important in the development of IgE immune responses in the normal host.
(10) Ribosomes programmed by different synonymous codons also differ in discriminating among near-cognate aminoacylated tRNAs.
(11) These results were then compared with CVB-specific IgM levels in the cognate patient sera.
(12) This line induces proliferation of and Ig secretion by I-Ak expressing but not H-2d resting and activated B cells as a result of cognate interactions.
(13) The protein has been designated as a stress cognate protein based on previous studies and data presented herein that this protein cross-reacted with a monoclonal antibody originally raised against the Drosophila 70 kilodalton heat shock protein.
(14) By radioactive in situ hybridization (ISH) using a fragment from the murine Pax-1 paired box that is almost identical to the respective sequences from the cognate human gene HuP48 and fluorescence in situ hybridization (FISH) using a complete mouse Pax-1 cDNA, we have assigned the human homologue of murine Pax-1, the PAX1 locus, to chromosome 20p.
(15) One region in most sigma factors makes sequence-specific contacts at the -10 region of its cognate promoters.
(16) This suggests that the SRE and its cognate protein are likely to be involved in the regulation of Krox-24 and presumably of other immediate-early serum response genes.
(17) A third Slp gene exists within this locus whose recombinant cognate did not express in L cells.
(18) Two of the hox appear to be cognates of the human Hu-1 (or mouse Hox 2.1) and the mouse Hox 1-3, while another is closely related to the mouse Hox 1-4.
(19) Comparison of our skeletal muscle translocator sequence with that of a recently published human fibroblast translocator cognate revealed that the two proteins are 88% identical and diverged about 275 million years ago.
(20) Comparison of the nucleotide and deduced amino acid sequence of this genome segment with cognate segments of isolates of BTV 1 from Australia and South Africa, and BTV 10 and BTV 17 from the United States, revealed homologies of 98%, 80%, 79%, and 79%, respectively, at the nucleotide level and 98%, 90%, 89%, and 90% identity, respectively, at the amino acid level.
Derivation
Definition:
(n.) A leading or drawing off of water from a stream or source.
(n.) The act of receiving anything from a source; the act of procuring an effect from a cause, means, or condition, as profits from capital, conclusions or opinions from evidence.
(n.) The act of tracing origin or descent, as in grammar or genealogy; as, the derivation of a word from an Aryan root.
(n.) The state or method of being derived; the relation of origin when established or asserted.
(n.) That from which a thing is derived.
(n.) That which is derived; a derivative; a deduction.
(n.) The operation of deducing one function from another according to some fixed law, called the law of derivation, as the of differentiation or of integration.
(n.) A drawing of humors or fluids from one part of the body to another, to relieve or lessen a morbid process.
Example Sentences:
(1) The interaction of the antibody with both the bacterial and the tissue derived polysialic acids suggests that the conformational epitope critical for the interaction is formed by both classes of compounds.
(2) The vascular endothelium is capable of regulating tissue perfusion by the release of endothelium-derived relaxing factor to modulate vasomotor tone of the resistance vasculature.
(3) Leumorphin is a 29-amino-acid peptide derived from preproenkephalin B. Intracerebroventricular (i.c.v.)
(4) A full-length cDNA encoding porcine heart aconitase was derived from lambda gt10 recombinant clones and by amplification of the 5' end of the mRNA.
(5) In animal experiments pharmacological properties of the low molecular weight heparin derivative CY 216 were determined.
(6) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(7) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
(8) PMNs could be primed for PMA-triggered oxidative burst by muramyl peptide molecules (MDP) and two of its adjuvant active nonpyrogenic derivatives.
(9) Recent studies have shown that an aberration in platelet-derived growth factor gene expression is unlikely to be a factor in proliferation of smooth-muscle cells.
(10) The macrophage-derived product, interleukin 1 (IL 1) is thought to play an important regulatory role in the proliferation of T lymphocytes; however, its mechanism of action is unknown.
(11) In the upper limb and facial forms of familial amyloidotic polyneuropathy first recorded in Swiss and Finns respectively, the differences in their patterns of neurological disease and ocular lesions could be the result of their amyloids deriving from proteins other than prealbumin.
(12) The antiproliferative activity of IFN was studied using the parental L cell line, a tk- derivative, and a tk- (tk+) subline into which the tk gene of herpes simplex virus was introduced.
(13) Bipolar derivations with the maximum PSE always included the locations with the maximum PSE obtained from a linked ears reference.
(14) Only those derivatives with a free amino group and net positive charge in the side chain were effective.
(15) Northern blot analysis with an 18-mer radiolabelled oligonucleotide, derived from an ALP specific cDNA clone, revealed a specific mRNA of about 700-800 nucleotides in HS-24 tumor cells.
(16) The mortality data were derived from the reports by Miyagi Prefectural Government.
(17) Ferrocene derivatives, in general, show a degree of versatility, coupling the electron-transfer reactions of many enzymes.
(18) The ADAM derivative of carnitine was separated from decomposition products of the reagent and related compounds such as amino acid derivatives on a silica gel column eluted with methanol-5% aqueous SDS-phosphoric acid (990:10:1).
(19) This doxorubicin derivative did not bind to Sepharose which was conjugated with cardiac actin.
(20) In the triploids, the 40 female chromosomes present (mouse, n = 20) were derived from a single diploid pronucleus formed after the extrusion of a first polar body, and following the monospermic fertilization of primary oocytes.