(a.) Allied by blood; kindred by birth; specifically (Law), related on the mother's side.
(a.) Of the same or a similar nature; of the same family; proceeding from the same stock or root; allied; kindred; as, a cognate language.
(n.) One who is related to another on the female side.
(n.) One of a number of things allied in origin or nature; as, certain letters are cognates.
Example Sentences:
(1) The use of sigma 54 promoters, known to require cognate binding proteins, could allow the fine-tuning that provides the temporal ordering of flagellar gene transcription.
(2) To date, a cognate action of E2 on the GnRH pulse generator has not been described.
(3) Cognate sites in genomes that diverged approximately 100 million years ago can be detected by PCR assays based on primer pairs from unique sequences.
(4) Cognate heat shock proteins might be involved in this renaturation process.
(5) LEW rats immunized with each of the three DA MHC chains produced alloantibodies to these chains, suggesting that indirect allorecognition did occur, because of the requirement for cognate recognition of B cells by T helper cells.
(6) Microcultures of helper T (Th) cells and a few appropriately primed murine B cells can be used to detect cognate T-B interactions which lead to clonal production of IgM, IgG1, and IgE.
(7) We have investigated the structural relationship of heat-inducible and cognate members of the human hsp70 gene family.
(8) If protein mixtures are subjected to affinity elution the cognate pair [tRNAPhe-phenylalanyl-tRNA synthetase] is eluted first, followed by noncognate pairs.
(9) These results suggest that cognate T-B cell interactions may be important in the development of IgE immune responses in the normal host.
(10) Ribosomes programmed by different synonymous codons also differ in discriminating among near-cognate aminoacylated tRNAs.
(11) These results were then compared with CVB-specific IgM levels in the cognate patient sera.
(12) This line induces proliferation of and Ig secretion by I-Ak expressing but not H-2d resting and activated B cells as a result of cognate interactions.
(13) The protein has been designated as a stress cognate protein based on previous studies and data presented herein that this protein cross-reacted with a monoclonal antibody originally raised against the Drosophila 70 kilodalton heat shock protein.
(14) By radioactive in situ hybridization (ISH) using a fragment from the murine Pax-1 paired box that is almost identical to the respective sequences from the cognate human gene HuP48 and fluorescence in situ hybridization (FISH) using a complete mouse Pax-1 cDNA, we have assigned the human homologue of murine Pax-1, the PAX1 locus, to chromosome 20p.
(15) One region in most sigma factors makes sequence-specific contacts at the -10 region of its cognate promoters.
(16) This suggests that the SRE and its cognate protein are likely to be involved in the regulation of Krox-24 and presumably of other immediate-early serum response genes.
(17) A third Slp gene exists within this locus whose recombinant cognate did not express in L cells.
(18) Two of the hox appear to be cognates of the human Hu-1 (or mouse Hox 2.1) and the mouse Hox 1-3, while another is closely related to the mouse Hox 1-4.
(19) Comparison of our skeletal muscle translocator sequence with that of a recently published human fibroblast translocator cognate revealed that the two proteins are 88% identical and diverged about 275 million years ago.
(20) Comparison of the nucleotide and deduced amino acid sequence of this genome segment with cognate segments of isolates of BTV 1 from Australia and South Africa, and BTV 10 and BTV 17 from the United States, revealed homologies of 98%, 80%, 79%, and 79%, respectively, at the nucleotide level and 98%, 90%, 89%, and 90% identity, respectively, at the amino acid level.
Sib
Definition:
(n.) A blood relation.
(a.) Related by blood; akin.
Example Sentences:
(1) The sexual attitudes and beliefs of 20 children who have been present at the labor and delivery of sibs and have observed the birth process are compared with 20 children who have not been present at delivery.
(2) We document four patients, including two sibs, with asphyxiating thoracic dystrophy and mild congenital hydrocephalus.
(3) However the study does not permit to reach any valid conclusions; further elaborate investigations alone could prove the useful role of genetic influence in the propagation of lepromin sensitivity to the subsequent sibs.
(4) The residual values were positively correlated in parent-offspring pairs and among sibs, both those presumed to be living together and those presumed to be living apart.
(5) A case of fragile-X syndrome (the Martin-Bell syndrome) in two male half-sibs from different marriages of their mother was described.
(6) No evidence was found of sex ratio anomalies in other classes of relative of pyloric stenosis index cases, whether or not the index cases had affected sibs.
(7) The ibd for grandparent-grandchild pairs is least affected by recombination, followed by sibs, half-sib, uncle-nephew, and first-cousin pairs.
(8) Nonagouti rats were significantly easier to approach, capture, and handle than their agouti sibs.
(9) This sib risk was apparent for probands with only a single hemivertebrum in addition to probands with more extensive vertebral defects and would support an etiological relationship between neural tube defects and other vertebral malformations.
(10) None of the sibs had BRA when the index case had BRA as part of a multiple malformation complex.
(11) probands and the estimated, future prevalence was found to be the same in sibs and children.
(12) The concept of LPC can also be used to interpret two factors which have been proposed to select for the Hamiltonian sex ratios: local mate competition is LPC acting through sons; and sib mating is LPC acting through daughters.
(13) We describe the concurrence of severe distal osteolysis, mental retardation, short stature, and characteristic facial appearance with maxillary hypoplasia and relative exophthalmos in two adult sibs, a 57-year-old woman and her deceased brother.
(14) To determine the relationship between so-called "diastrophic variant" and diastrophic dysplasia, four patients considered to have the variant condition were studied in detail and compared to 67 patients (including 17 sets of affected sibs) considered to have classical diastrophic dysplasia.
(15) The affected sib pair method revealed that in asthmatic families chi 2 = 4.9 (no significance) and in DF-specific IgE positive families chi 2 = 6.2 (p less than 0.05).
(16) CP proband frequencies of .004 for maternal half sibs and .009 for the paternal counterparts were also found.
(17) There is an early-onset form (with onset of symptoms under 2 years of age) where the illness is milder but more persistent, and where there is frequent occurrence of myasthenia in sibs.
(18) The increase is found with estimates of h2 based both on offspring mid-parent regression and on half sib analyses, but may be more marked with the former.
(19) Cumulative risk estimates were 26% for sibs born after the proband and 11% for sibs born before the proband (p less than 0.001).
(20) The one in three risk of spondylolysis to near relatives of patients with the dysplastic form of spondylolisthesis is emphasised in order that the deformity in their sibs and children can be recognised at any early age.