(v. t.) To wind cylindrically or spirally; as, to coil a rope when not in use; the snake coiled itself before springing.
(v. t.) To encircle and hold with, or as with, coils.
(v. i.) To wind itself cylindrically or spirally; to form a coil; to wind; -- often with about or around.
(n.) A ring, series of rings, or spiral, into which a rope, or other like thing, is wound.
(n.) Fig.: Entanglement; toil; mesh; perplexity.
(n.) A series of connected pipes in rows or layers, as in a steam heating apparatus.
(n.) A noise, tumult, bustle, or confusion.
Example Sentences:
(1) The building block of cytokeratin IFs is a heterotypic tetramer, consisting of two type I and two type II polypeptides arranged in pairs of laterally aligned coiled coils.
(2) Right hepatic artery embolization with three coils was performed.
(3) The potential use of ancrod, a purified isolate from the venom of the Malaysian pit viper, Agkistrodon rhodostoma, in decreasing the frequency of cyclic flow variations in severely stenosed canine coronary arteries and causing thrombolysis of an acute coronary thrombus induced by a copper coil was evaluated.
(4) Chloride caused a significant concentration-dependent shortening of myosin rods due to destabilization of the alpha-helical double coiled rod structure.
(5) The tinsel coiled around a jug of squash and bauble in the strip lighting made a golf-ball size knot of guilt burn in my throat.
(6) The "random coil" conformational problem is examined by comparison of vibrational CD (VCD) spectra of various polypeptide model systems with that of proline oligomers [(Pro)n] and poly(L-proline).
(7) Carcinogen-modified oligodeoxynucleotides were single-stranded, but there were often considerable stacking interactions between the pyrenyl residues and the oligonucleotide bases, indicating that electrophoresed oligomers were single-stranded but in a native, versus random coil, conformation.
(8) We measured the magnetic fields produced by several different coils and compared the results with theoretical calculations.
(9) The predicted protein shares significant homology with lamins A and C and other members of the intermediate filament family of proteins, and shares features important for the coiled-coil structure proposed for these proteins.
(10) These design methods are suited for constructing the most efficient gradient coil that meets a specified homogeneity requirement.
(11) Echocardiograms showed good left ventricular function and a large coil of apparent thrombus in the right atrium prolapsing into the right ventricle.
(12) In some cases, an intracytoplasmic coiling of the tail or tails could be observed.
(13) We studied effects of this anomaly on ocular motility using electro-oculography and the magnetic search-coil technique.
(14) The force of the inflow is considerable and can alter the shape of coils and displace both coils and balloons positioned within the aneurysm.
(15) The results are not consistent with a straight chain of nucleosomes and require the presence of a higher order coiling in monovalent salt solutions.
(16) Closely coupled receiver coils can provide a useful improvement in MR image quality.
(17) We report our clinical experience with nearly 100 patients in the first year in the special surface-coil approach of orbit and knee joint.
(18) van't Hoff plots of the thermal denaturation data gave enthalpies for the helix-coil transition of 21,600 cal (ca.
(19) Technical considerations for the magnetic resonance imaging of the foot and ankle are discussed, including the selection of the appropriate surface coil, the importance of stabilizing the anatomic region, and the principles guiding the choice of pulse sequences.
(20) Complete atrophy of variable lengths of the terminal basal coil cells was also found in all elderly cochleas.
Helix
Definition:
(n.) A nonplane curve whose tangents are all equally inclined to a given plane. The common helix is the curve formed by the thread of the ordinary screw. It is distinguished from the spiral, all the convolutions of which are in the plane.
(n.) A caulicule or little volute under the abacus of the Corinthian capital.
(n.) The incurved margin or rim of the external ear. See Illust. of Ear.
(n.) A genus of land snails, including a large number of species.
Example Sentences:
(1) The presence of a few key residues in the amino-terminal alpha-helix of each ligand is sufficient to confer specificity to the interaction.
(2) The elongation of helix III with the addition of helix II at the N-terminus somewhat stabilizes the ordered structure.
(3) The C-terminal sequence contains an amphiphilic alpha-helix of four turns which lies on the surface of the beta-barrel.
(4) The chiral intercalators, at micromolar concentrations, inhibit the reaction of EcoRI, but for each enantiomeric pair it is the lambda enantiomer, which binds only poorly to a B-DNA helix, that inhibits EcoRI preferentially.
(5) The melting profile exhibited two transitions--one at about 35 degrees C and one above 50 degrees C. Our spectral data showed that helices I and II were stable during the first transition, and agreed with other data that helix III was the most likely helix to have melted.
(6) The helix axes, penetrating the hydrophobic region of the bilayers, were oriented neither parallel nor perpendicular to the membrane normal.
(7) The structure of the Z-helix antigen was confirmed by circular dichroism (CD) and U.V.
(8) Conformational predictions based on these sequences confirm their structural homology and indicate the probable existence of two beta-turns, one beta-chain and a long alpha-helix in them.
(9) The nogalose and aminoglucose sugars lie in the minor and major grooves, respectively, of the distorted B-DNA double helix.
(10) The latter, which is external and solvent accessible, is associated with a distortion in the alpha-helix centered around Tyr33 which consists of a significant increase in the CO(i-4)-N(i) and CO(i-4)-NH(i) distances relative to those in the rest of the helix, as well as a significant departure in the phi, psi angles of Tyr33 relative to regular helical geometry.
(11) The AFB1 moiety is face-stacked in the major groove with its long axis approximately perpendicular to the helix axis.
(12) MP8 also was conformed as an alpha-helix, but was amphipatic in the sense that the N-terminal half of the molecule was hydrophilic and the C-terminal half hydrophobic.
(13) A lectin, Helix pomatia agglutinin (HPA), was planted at the surface of rat GEN by the perfusion of the isolated left kidney with neuraminidase (NRD) and HPA.
(14) As a basis for the discussion a possible structure for the DNA complex of the phenylated neutral red is considered in which the extra phenyl ring at N-5 of the phenazinium system, protrudes into the large groove of the DNA helix while the tricyclic part of the ligand is inserted between the DNA base-pairs.
(15) The opsin mutations included reversal of a charged pair conserved in all G protein-coupled receptors at the cytoplasmic border of the third transmembrane helix (mutant CD1), replacement of 13 amino acids in the second cytoplasmic loop (mutant CD2), and deletion of 13 amino acids from the third cytoplasmic loop (mutant EF1).
(16) The remaining 26 independently isolated second-site suppressor mutations all mapped within the amino-terminal DNA binding domain of LexA, at positions 22 (situated in the turn between helix 1 and helix 2) and positions 57, 59, 62, 71 and 73.
(17) In subsequent steps, unassociated Y' directs the synthesis of the complementary oligopurine (R') strand forming a new double helix Y'R' that may direct the synthesis of an oligopyrimidine strand, Y, that is expected to be identical to the first strand that started the whole sequence.
(18) Z-DNA antigen was prepared against poly(dG-dC).poly(dG-dC), which had been converted to the Z-helix conformation in high salt and then stabilized by bromination.
(19) Incubation and heating of the polymers in 1 mM Mn2+ caused the spectral shift reported for the left-handed Z-DNA conformation in the alternating copolymer and the change reported for the triple helix in the homopolymer.
(20) To investigate the ability of a protein to accommodate potentially destabilizing amino acid substitutions, and also to investigate the steric requirements for catalysis, proline was substituted at different sites within the long alpha-helix that connects the amino-terminal and carboxyl-terminal domains of T4 lysozyme.