What's the difference between coinheritance and joint?
Coinheritance
Definition:
(n.) Joint inheritance.
Example Sentences:
(1) When the biochemical defect is unknown, a gene can be located only through molecular approaches based on coinheritance (genetic linkage) of the disease phenotype with a particular allele of a polymorphic DNA marker that has already been mapped to a specific chromosomal region.
(2) Coinheritance of these defects apparently produced severe hypercholesterolemia in the offspring.
(3) Formal linkage analysis was applied to test for coinheritance of disease with the HLA locus within families.
(4) This suggests that a single genetic mutation that usually has a recessive effect on lipoprotein metabolism can have an interactive effect on lipid phenotype when it is coinherited with a single mutation at another gene whose product affects the same metabolic pathway.
(5) The significance of the linkage detected between the disease locus and polymorphic loci was assessed by calculating a lod score (the logarithm of the probability of observing coinheritance of two loci, assuming that they are genetically linked, divided by the probability of detecting coinheritance if they are unlinked).
(6) Linkage studies have indicated that the coinheritance frequencies are less than would be expected from the published molecular weight of E79 deoxyribonucleic acid (120 X 10(6).
(7) The variable levels of HbF in sickle cell anemia reflect the heterogeneous genetic mix of the beta s-gene-cluster haplotypes and coinheritance of alpha-thalassemia-2 in American SS patients.
(8) Mapping of tox markers was accomplished by scoring for the frequency of coinheritance of the donor tox allele with selected and unselected donor markers.
(9) The findings suggest coinheritance of high blood cholesterol and increased susceptibility to CHD.
(10) Coinheritance analysis demonstrated that five of the other transformants harbored a 100-kb segment of the cloned human insert.
(11) Coinheritance of these disorders with other beta chain hemoglobinopathies, such as beta thalassemia and the sickle cell (beta s) gene, can result in attenuation of the clinical severity of these hemoglobinopathies owing to the increased Hb F levels.
(12) Phenytoin pharmacokinetics exhibit large intersubject differences and coinheritance of phenytoin metabolism with known drug hydroxylation polymorphisms was therefore suspected.
(13) This occurred after coinheritance of alpha+ thalassaemia and APKD, which resulted in an altered band size for the (+) RsaI restriction fragment length polymorphism.
(14) The n locus is closely linked to the other six defined loci in the heavy chain chromosomal region and the allelic alternatives for each of the seven loci are coinherited by gene combinations called allogroups.
(15) From coinheritance analysis of the ERCC-3 region in independent transformants, we deduce that the gene has a size of 35 to 45 kilobases, of which one essential segment has so far been refractory to cloning.
(16) Further modulation of the clinical course by the coinheritance of alpha-thalassemia-2 tends to decrease the risk of soft tissue organ failure but increases the risk of osteonecrosis.
(17) When the coinheritance of alpha thalassaemia is suspected, it is necessary to examine carefully the red blood cell distribution of a placental sample, so that the presence of a population of fetal red blood cells is not missed.
(18) The coinheritance of alpha-thalassemia-2 further decreases the risk of major morbidity of the soft tissues but increases the risk of avascular necrosis of the bony skeleton.
(19) Determinants recognized to date as able to produce mild forms of beta-thalassemias, are beta-thalassemia mutations with a high residual output of beta-globin chain production, coinheritance of alpha-thalassemia or nondeletion HPFH linked or not linked to the beta-globin gene cluster, delta beta thalassemias and specific beta-globin haplotype.
(20) The coinheritance of alpha-thalassemia (alpha-thal) and sickle cell anemia provides a most interesting example of how separate globin gene mutations influence clinical manifestations of abnormal gene expression.
Joint
Definition:
(n.) The place or part where two things or parts are joined or united; the union of two or more smooth or even surfaces admitting of a close-fitting or junction; junction as, a joint between two pieces of timber; a joint in a pipe.
(n.) A joining of two things or parts so as to admit of motion; an articulation, whether movable or not; a hinge; as, the knee joint; a node or joint of a stem; a ball and socket joint. See Articulation.
(n.) The part or space included between two joints, knots, nodes, or articulations; as, a joint of cane or of a grass stem; a joint of the leg.
(n.) Any one of the large pieces of meat, as cut into portions by the butcher for roasting.
(n.) A plane of fracture, or divisional plane, of a rock transverse to the stratification.
(n.) The space between the adjacent surfaces of two bodies joined and held together, as by means of cement, mortar, etc.; as, a thin joint.
(n.) The means whereby the meeting surfaces of pieces in a structure are secured together.
(a.) Joined; united; combined; concerted; as joint action.
(a.) Involving the united activity of two or more; done or produced by two or more working together.
(a.) United, joined, or sharing with another or with others; not solitary in interest or action; holding in common with an associate, or with associates; acting together; as, joint heir; joint creditor; joint debtor, etc.
(a.) Shared by, or affecting two or more; held in common; as, joint property; a joint bond.
(v. t.) To unite by a joint or joints; to fit together; to prepare so as to fit together; as, to joint boards.
(v. t.) To join; to connect; to unite; to combine.
(v. t.) To provide with a joint or joints; to articulate.
(v. t.) To separate the joints; of; to divide at the joint or joints; to disjoint; to cut up into joints, as meat.
(v. i.) To fit as if by joints; to coalesce as joints do; as, the stones joint, neatly.
Example Sentences:
(1) It is likely that trunk mobility is necessary to maintain integrity of SI joint and that absence of such mobility compromises SI joint structure in many paraplegics.
(2) The sequential histopathologic alterations in femorotibial joints of partial meniscectomized male and female guinea pigs were evaluated at 1, 2, 3, 6, and 12 weeks post-surgery.
(3) Compared with conservative management, better long-term success (determined by return of athletic soundness and less evidence of degenerative joint disease) was achieved with surgical curettage of elbow subchondral cystic lesions.
(4) On Friday, a spokesperson for China’s foreign ministry appeared to confirm those fears, telling reporters that the joint declaration, a deal negotiated by London and Beijing guaranteeing Hong Kong’s way of life for 50 years, “was a historical document that no longer had any practical significance”.
(5) Based upon the analysis of 1015 case records of patients, aged 16-70, with different hip joint pathology types, carried out during 1985-1990, there were revealed mistakes and complications after reconstructive-restorative operations.
(6) By measurement and analysis of the changes in carpal angles and joint spaces, carpal instability was discovered in 41 fractures, an incidence of 30.6%.
(7) Apart from their pathogenic significance, these results may have some interest for the clinical investigation of patients with joint diseases.
(8) Formation of the functional contour plaster bandage within the limits of the foot along the border of the fissure of the ankle joint with preservation of the contours of the ankles 4-8 weeks after the treatment was started in accordance with the severity of the fractures of the ankles in 95 patients both without (6) and with (89) dislocation of the bone fragments allowed to achieve the bone consolidation of the ankle fragments with recovery of the supportive ability of the extremity in 85 (89.5%) of the patients, after 6-8 weeks (7.2%) in the patients without displacement and after 10-13 weeks (11.3%) with displacement of the bone fragments of the ankles.
(9) Clinical evaluation of passive range of motion, antero-posterior laxity and the appearance of the joint space showed little or no difference between the reconstruction methods.
(10) This system may serve as a model to explain the mechanisms by which cells accumulate in inflamed joints.
(11) On the basis of these data, the computer, upon the basis of a program specially developed for this purpose, automatically calculates the corresponding amount of negative-points, which parallels the severity of the joint changes, i.e.
(12) The prognosis of meningococcal arthritis is excellent and joint sequelae are rare.
(13) In the anatomy laboratory we looked for an alternative approach to the glenohumeral joint which would accommodate these difficulties.
(14) These two enzymes may act jointly in filling up the gaps along the DNA molecule and elongating the DNA chain.
(15) The results of conventional sciatic nerve stretching tests are usually evaluated regardless of patient age, gender or movements of the hip joint and spine.
(16) The correlation of posterior intervertebral (facet) joint tropism (asymmetry), degenerative facet disease, and intervertebral disc disease was reviewed in a retrospective study of magnetic resonance images of the lumbar spine from 100 patients with complaints of low back pain and sciatica.
(17) Hypermobility and instability following injury and degenerative joint disease is poorly understood and often not recognized as the cause of the patients symptoms.
(18) One middle carpal joint of each horse was injected 3 times with 100 mg of 6-alpha-methylprednisolone acetate, at 14-day intervals.
(19) In a clear water reservoir built in ready construction after a working-period of five months quite a lot of slime could be found on the expansion joint filled with tightening compound on the base of Thiokol.
(20) Cable argued that the additional £30bn austerity proposed by the chancellor after 2015 went beyond the joint coalition commitment to eradicate the structural part of the UK's current budget deficit – the part of non-investment spending that will not disappear even when the economy has fully emerged from the recession of 2008-09.