(n.) Deprived of heat, or having a low temperature; not warm or hot; gelid; frigid.
(n.) Lacking the sensation of warmth; suffering from the absence of heat; chilly; shivering; as, to be cold.
(n.) Not pungent or acrid.
(n.) Wanting in ardor, intensity, warmth, zeal, or passion; spiritless; unconcerned; reserved.
(n.) Unwelcome; disagreeable; unsatisfactory.
(n.) Wanting in power to excite; dull; uninteresting.
(n.) Affecting the sense of smell (as of hunting dogs) but feebly; having lost its odor; as, a cold scent.
(n.) Not sensitive; not acute.
(n.) Distant; -- said, in the game of hunting for some object, of a seeker remote from the thing concealed.
(n.) Having a bluish effect. Cf. Warm, 8.
(n.) The relative absence of heat or warmth.
(n.) The sensation produced by the escape of heat; chilliness or chillness.
(n.) A morbid state of the animal system produced by exposure to cold or dampness; a catarrh.
(v. i.) To become cold.
Example Sentences:
(1) The judge, Mr Justice John Royce, told George she was "cold" and "calculating", as further disturbing details of her relationship with the co-accused, Colin Blanchard and Angela Allen, emerged.
(2) Video games specialist Game was teetering on the brink of collapse on Friday after a rescue deal put forward by private equity firm OpCapita appeared to have been given the cold shoulder by lenders who are owed more than £100m.
(3) "There is a serious risk that a deal will be agreed between rich countries and tax havens that would leave poor countries out in the cold.
(4) Results demonstrate that the development of biliary strictures is strongly associated with the duration of cold ischemic storage of allografts in both Euro-Collins solution and University of Wisconsin solution.
(5) These data suggest that submaximal exercise and cold air exposure enhance nonspecific bronchial reactivity in asthmatic but not in normal subjects.
(6) The relationship between cold-insoluble complexes, or cryoglobulins, and renal disease was studied in rabbits with acute serum sickness produced with BSA.
(7) Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1983, pp.
(8) Changes in pain tolerance after administration of differently labelled placebos were studied by measuring the reaction time after a cold stimulus.
(9) The quality of liver grafts was evaluated using an original, blood-free isolated perfusion model, after 8 h cold storage, or after 15 min warm ischemia performed prior to harvesting.
(10) Lymphocytes of inbred mice immunized with allogenic tumour cells were labelled in vitro or in vivo by 3H-thymidine, washed out and incubated with target cells in the presence of "cold" thymidine.
(11) The binding of 125I-labeled core protein to immobilized fibronectin was inhibited by soluble fibronectin and by soluble cold core protein but not by albumin or gelatin.
(12) "The government should be doing all it can to put the UK at the forefront of this energy revolution not blowing hot and cold on the issue.
(13) 1, diarrhea lowered the piglet's ability to maintain body temperature during the cold test.
(14) 3H-uridine or 3H-uracil with cold uridine and uracil, respectively, in amounts corresponding to therapeutic doses of these two pyrimidines as fluoro compounds, were administered with or without microspheres.
(15) To a large extent, the failure has been a consequence of a cold war-style deadlock – Russia and Iran on one side, and the west and most of the Arab world on the other – over the fate of Bashar al-Assad , a negotiating gap kept open by force in the shape of massive Russian and Iranian military support to keep the Syrian regime in place.
(16) For a union that, in less than 25 years, has had to cope with the end of the cold war, the expansion from 12 to 28 members, the struggle to create a single currency and, most recently, the eurozone crisis, such a claim risks accusations of hyperbole.
(17) A comparison is made between these results and those of other authors who observed microtubule disaggregation by cold with the electron microscope.
(18) Raised cold agglutinin titres were observed in 16 patients with atypical pneumonia.
(19) This initial observation of release of eosinophil chemotactic factor of anaphylaxis in vivo along with histamine assigns the mast cell a central role in cold urticaria.
(20) Detection limits were then calculated for the different sizes of cold spots.
Icy
Definition:
(superl.) Pertaining to, resembling, or abounding in, ice; cold; frosty.
(superl.) Characterized by coldness, as of manner, influence, etc.; chilling; frigid; cold.
Example Sentences:
(1) The dog and the pig also have an endoperoxide-sensitive constrictor system activated by the 11,9-(epoxymethano) analogue of PGH2 and, of particular note, ICI 79939 and its 11-oxo analogue.
(2) The second experiments entailed use of the nonspecific opiate antagonist, naloxone, as well as the specific delta antagonist, ICI 154,129, against seizures induced by icv-administered morphine, morphiceptin, DADL, or DSLET.
(3) Leading clinical candidates have emerged from Smith Kline and French, Lilly, Merck-Frosst, ICI-Stuart and other groups.
(4) ICI 74 205, a synthetic analogue of prostaglandin F2 alpha (PGF2a) with an alkyl side chain extended by an ethyl group, was administered intravenously in 6 patients using normal saline as the vehicle.
(5) However, the pressor response to the stressors was greater in ICI 118,551- than vehicle-treated F1, but the tachycardia was equivalent for both groups.
(6) Rapid cellular uptake and metabolism of polyglutamate forms that are approximately 100-fold more potent as inhibitors of TS can translate a modest TS inhibitor such as ICI D1694 into a very potent inhibitor of cell growth (approximately 500- and approximately 10-fold more potent than CB3717 or ICI 198583, respectively).
(7) Naloxone affected CS levels in control mice and appeared to reduce the CS response to stress: ICI 154,129 and ICI 174,864 did not produce consistent effects on plasma CS levels.
(8) Treatment of hamsters with the same protocol and doses of ICI 200,880 for 8 wk prevented the destructive lesion induced by a single intratracheal dose of HNE.
(9) Tamoxifen (ICI 46474) is the trans-isomer of 1(p-beta-dimethylaminoethoxy-phenyl)-1, 2-diphenylbut-1-ene.
(10) However, with 50 nM ICI 118551 there was a reduction in the maximum response to isoprenaline.
(11) The effect of methallibure (ICI 33828) on spermatogenesis was studied in the gerbil, hedgehog, and mouse.
(12) The two LTD4 receptor antagonists (MK-571 and ICI-204,219) significantly reduced the permeability changes induced by indomethacin, while the two LTB4 antagonists (SC-41930 and LY-255,283) were without significant effect.
(13) Using a double-blind, placebo-controlled crossover design, we tested the hypothesis that the LTD4 receptor antagonist, ICI 204,219, could inhibit LTD4-induced bronchoconstriction in normal subjects.
(14) However, a glutamate antagonist (MK801) and three serotonin antagonists (ritanserin, ketanserin and ICI 170,809) were all unable to alter the MPTP effects, at the doses used in our study.
(15) However, the ICI-ER complexes that remain are in sufficient quantity to bind to gene activation reporter constructs, and in these cells, ICI still behaves as a pure antagonist of gene transcription and does not activate reporter genes.
(16) Only ICI 111,581 (5 mg kg-1) and propranolol (1 and 10 mg kg-1) prolonged P-R interval.
(17) After 7 injections of Zoladex Depot (ICI Pharma, Heidelberg, Germany), the uterus was reduced to normal size carrying dorsally a myoma of the same size.
(18) Pulse-chase experiments indicate that the half-life of the receptor is reduced from approximately 5 hr in the presence of estradiol to less than 1 hr by ICI 164,384.
(19) Plasma concentrations of AUC for ICI 169, 369 were low.
(20) The compound ICI 164,384 [N-n-butyl-N-methyl-11-(3,17 beta-dihydroxyoestra-1,3,5(10)-trien-7 alpha-yl) undecamide] was entirely devoid of oestrogenic activity in the rat and mouse uterus but completely blocked the uterine stimulatory effects of oestradiol and of tamoxifen.