(v. i.) To fall together suddenly, as the sides of a hollow vessel; to close by falling or shrinking together; to have the sides or parts of (a thing) fall in together, or be crushed in together; as, a flue in the boiler of a steam engine sometimes collapses.
(v. i.) To fail suddenly and completely, like something hollow when subject to too much pressure; to undergo a collapse; as, Maximilian's government collapsed soon after the French army left Mexico; many financial projects collapse after attaining some success and importance.
(n.) A falling together suddenly, as of the sides of a hollow vessel.
(n.) A sudden and complete failure; an utter failure of any kind; a breakdown.
(n.) Extreme depression or sudden failing of all the vital powers, as the result of disease, injury, or nervous disturbance.
Example Sentences:
(1) As collapse was imminent, MAP increased but CO and TPR did not change significantly.
(2) Video games specialist Game was teetering on the brink of collapse on Friday after a rescue deal put forward by private equity firm OpCapita appeared to have been given the cold shoulder by lenders who are owed more than £100m.
(3) Meeting after meeting during 2011 to try to hammer out agreements about the basic shape of the Egyptian constitution – meetings that always mysteriously collapsed.
(4) Poor workplace health and safety, inadequate toilet facilities and dangerous fumes from mosquito fogging that led to one asylum seeker with asthma collapsing were all raised as concerns by Kilburn, although he stressed that he believed G4S management and expatriate G4S staff acted appropriately.
(5) The ATPase inhibitor dicyclohexylcarbodiimide, which collapsed the chemical and electrical components of the proton motive force, caused rapid cell swelling in the presence of glucose (and high intracellular ATP levels).
(6) Cobra collapsed into administration in 2009 after which Lord Bilimoria was criticised for using a “pre-pack” deal to buy back a stake in the firm.
(7) For the next three years, Foxtons suffered collapsing sales and staff culls.
(8) Sometimes it can seem as if the history of the City is the history of its crises and disasters, from the banking crisis of 1825 (which saw undercapitalised banks collapse – perhaps the closest historic parallel to the contemporary credit crunch), through the Spanish panic of 1835, the railway bust of 1837, the crash of Overend Gurney, the Kaffir boom, the Westralian boom, the Marconi scandal, and so on and on – a theme with endless variations.
(9) The Rio+ 20 Earth summit could collapse after countries failed to agree on acceptable language just two weeks before 120 world leaders arrive at the biggest UN summit ever organised, WWF warned on Wednesday.
(10) Dicyclohexylcarbodiimide (DCCD) inhibits this carrier in a time- and concentration -dependent manner as shown by the following evidence: it inhibits the carrier-mediated pH gradient driven monoamine uptake without collapsing the pH gradient; it affects the binding of the specific inhibitors [2-3H]dihydrotetrabenazine and [3H]reserpine.
(11) After completion of the hepatectomy, he developed circulatory collapse of unknown cause and died shortly after the operation.
(12) Secularism is the only way to stop collapse and chaos and to foster bonds of citizenship in our complex democracy.
(13) In such cases, hypertension must be controlled with phentolamine or sodium nitroprusside, cardiac arrhythmia with lignocaine, and collapse with volaemic expansion.
(14) Two conditions must be fulfilled: a lesion of a non collapsible vein; and a pressure gradient from outside to inside the vein, as occurs for instance during puncture of a large vein in a hypovolemic patient.
(15) Gastroduodenal investigation must of course be comprised of pictures during collapse, semi-collapse and repletion of the entire duodenal outline; once out of every two times, one has to recourse to intravenous duodenography which has become a routine investigation.
(16) When communism collapsed at the end of the 1980s and the sledgehammers started to thud into the Berlin Wall, the future for laissez-faire economics was brighter than it had been since 1914.
(17) Emergency teams are still working to reconnect 10,000 households in northern England which lost power in blizzards and gales, after all-night repairs on collapsed cables which left 80,000 cut off.
(18) In 4 persons the test had to be stopped because of collapse.
(19) Peacocks , the budget fashion chain, has fallen into administration, putting 9,600 jobs at risk, after a management buyout deal collapsed at the last minute.
(20) Nuclear pyknosis was seen in cortical cells of animals dying in collapse.
Fold
Definition:
(v. t.) To lap or lay in plaits or folds; to lay one part over another part of; to double; as, to fold cloth; to fold a letter.
(v. t.) To double or lay together, as the arms or the hands; as, he folds his arms in despair.
(v. t.) To inclose within folds or plaitings; to envelop; to infold; to clasp; to embrace.
(v. t.) To cover or wrap up; to conceal.
(v. i.) To become folded, plaited, or doubled; to close over another of the same kind; to double together; as, the leaves of the door fold.
(v.) A doubling,esp. of any flexible substance; a part laid over on another part; a plait; a plication.
(v.) Times or repetitions; -- used with numerals, chiefly in composition, to denote multiplication or increase in a geometrical ratio, the doubling, tripling, etc., of anything; as, fourfold, four times, increased in a quadruple ratio, multiplied by four.
(v.) That which is folded together, or which infolds or envelops; embrace.
(n.) An inclosure for sheep; a sheep pen.
(n.) A flock of sheep; figuratively, the Church or a church; as, Christ's fold.
(n.) A boundary; a limit.
(v. t.) To confine in a fold, as sheep.
(v. i.) To confine sheep in a fold.
Example Sentences:
(1) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(2) 5-Azacytidine (I) stability was increased approximately 10-fold over its stability in water or lactated Ringer injection by the addition of excess sodium bisulfite and the maintenance of pH approximately 2.5.
(3) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(4) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
(5) The DNA untwisting enzyme has been purified approximately 300-fold from rat liver nuclei.
(6) IP3 increased 1.7-fold and IP2 1.6-fold after 20 and 40 s, respectively.
(7) Short incubations with heparin (5 min) caused a release of the enzyme into the media, while longer incubations caused a 2-8-fold increase in net lipoprotein lipase secretion which was maximal after 2-16 h depending on cell type, and persisted for 24 h. The effect of heparin was dose-dependent and specific (it was not duplicated by other glycosaminoglycans).
(8) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(9) Epicanthal folds were present in 46%, mongoloid slanting of the lids in 72% of cases.
(10) The estimated DNA compaction ratio (approximately 3-fold) is consistent with a significant degree of nucleosome unfolding in the hyperstimulated BR genes.
(11) Two hours after refeeding rats fasted for 48 h, ODC activity increased 40-fold in mucosa from the intact jejunum and 4-fold in the mucosa of the bypassed segments.
(12) Transfection of the treated DNA into SOS-induced spheroplasts results in an increase in mutagenesis as great as 50-fold.
(13) ACh released from the vesicular fraction was about 100-fold more than could be accounted for by miniature end-plate potentials; possible causes of this overestimate are discussed.
(14) In strains completely deleted for galR, the gene which encodes the Gal repressor, the operon is derepressed by only 10-fold without an inducer.
(15) The amount of water, creatinine, electrolytes, proteins, and enzymes were higher during the day (up to three fold, p always less than 0.05), while equal amounts of amino acids were excreted in the day and the night period.
(16) TNBS reacts to an extremely small extend with hemoglobin over the concentration range 0.4 to 4 mM whereas FDNB reacts with hemoglobin to a very large extent (50 fold more than TNBS).
(17) Rates of PC in vitro metabolism by liver and kidney cytosolic cysteine conjugate beta-lyases (beta-lyases) were similar, but metabolism by renal mitochondrial beta-lyase occurred at a 3-fold higher rate than the rate obtained with hepatic mitochondrial beta-lyase.
(18) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
(19) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(20) The gene, which is located at chromosome XIII, is transcribed as a mRNA of about 2.7 kilobases, and the amount of message has been found to increase 3- to 4-fold during the culture.