What's the difference between colocynth and egusi?
(n.) The light spongy pulp of the fruit of the bitter cucumber (Citrullus, / Cucumis, colocynthis), an Asiatic plant allied to the watermelon; coloquintida. It comes in white balls, is intensely bitter, and a powerful cathartic. Called also bitter apple, bitter cucumber, bitter gourd.
(1) Naturally-occurring agonists at this receptor may include members of the cathartic class of drugs such as colocynth, chrysarobin, etc.
(2) We report three examples of toxic acute colitis which occurred after ingestion of colocynth (Citrullus colocynthis) for ritual purposes.
(3) It is suggested that the colitis was caused by the ingestion of colocynth.
(4) A causal relationship between colonic injury and the intake of colocynth was supported by the following features: (1) the pharmacology of the colocynth extract ingested; (2) the temporal relationship between colocynth intake and clinical onset (eight to 12 h); (3) the rapid recovery within three to six days, with normal endoscopy at day 14; (4) the absence of other possible causes for the observed patterns, except in one case, in which a concomitant intestinal infection with Clostridium perfringens Type A was discovered; (5) the specific pathological features.
(5) Colonic biopsies taken 27, 44, and 72 h after colocynth intake showed: erosions with fibrino-purulent exudate, early fibrosis of the lamina propria, hyaline thickening of the superficial epithelial basal membrane.
(6) A 61-year-old woman presented with an acute condition involving confusion, abdominal cramps and bloody diarrhea six hours after accidental ingestion of colocynth mistaken for zucchini.