What's the difference between colocynth and laxative?
Colocynth
Definition:
(n.) The light spongy pulp of the fruit of the bitter cucumber (Citrullus, / Cucumis, colocynthis), an Asiatic plant allied to the watermelon; coloquintida. It comes in white balls, is intensely bitter, and a powerful cathartic. Called also bitter apple, bitter cucumber, bitter gourd.
Example Sentences:
(1) Naturally-occurring agonists at this receptor may include members of the cathartic class of drugs such as colocynth, chrysarobin, etc.
(2) We report three examples of toxic acute colitis which occurred after ingestion of colocynth (Citrullus colocynthis) for ritual purposes.
(3) It is suggested that the colitis was caused by the ingestion of colocynth.
(4) A causal relationship between colonic injury and the intake of colocynth was supported by the following features: (1) the pharmacology of the colocynth extract ingested; (2) the temporal relationship between colocynth intake and clinical onset (eight to 12 h); (3) the rapid recovery within three to six days, with normal endoscopy at day 14; (4) the absence of other possible causes for the observed patterns, except in one case, in which a concomitant intestinal infection with Clostridium perfringens Type A was discovered; (5) the specific pathological features.
(5) Colonic biopsies taken 27, 44, and 72 h after colocynth intake showed: erosions with fibrino-purulent exudate, early fibrosis of the lamina propria, hyaline thickening of the superficial epithelial basal membrane.
(6) A 61-year-old woman presented with an acute condition involving confusion, abdominal cramps and bloody diarrhea six hours after accidental ingestion of colocynth mistaken for zucchini.
Laxative
Definition:
(a.) Having a tendency to loosen or relax.
(a.) Having the effect of loosening or opening the intestines, and relieving from constipation; -- opposed to astringent.
(n.) A laxative medicine. See the Note under Cathartic.
Example Sentences:
(1) There was a history of facial edema and constipation, which have been managed with "Kanpo medicine (Chinese medicine)" and laxatives for several years.
(2) There was no significant difference between the laxatives used.
(3) IN EXAMINATION OF THE SMALL INTESTINE, SHORTENED TRANSIT TIME AND IMPROVED QUALITY WERE ACHIEVED BY USING THE FOLLOWING ITEMS OF REGIMEN: 1, No laxative; 2, nothing by mouth for 8 hours before examination; 3, 600 ml of micropulverized barium sulfate; 4, patient to lie in right decubitus position for at least one hour between films; and 5, ingestion of 200 ml of cool tap water a half hour after the start of the examination.
(4) Patients were then randomized in 2 groups, both receiving standard treatment during 2 months (low-salt diet--70 to 90 mEq of Na per day, stopping diuretics and laxatives, elastic stockings).
(5) In all patients careful bowel preparation was carried out by low residue diet, laxatives, enemas and antibiotics.
(6) Urinary data indicate that a large percentage (50%) of the drug was eliminated renally despite administration of multiple doses of activated charcoal, cholestyramine and hyperosmotic laxatives.
(7) In contrast to manometry, electromyographic methods using an endoluminal probe enable continuous colonic motor recordings over a long colonic segment for at least 24 h, and consequently studies following the course of laxative effects after oral administration, the classical therapeutic route, are possible.
(8) In contrast, the laxative potentiated the responses of the longitudinal muscle of guinea-pig isolated ileum and the rat stomach strip to the agonists, particularly PGE2.
(9) Stimulation of peristalsis or a decrease of intraluminal pressure has been described manometrically after intraluminal administration of laxatives including senna.
(10) The aim of the present investigation is therefore to study the absorption and the plasma level profile and to correlate plasma level profile and laxative effect after the administration of various dosage forms.
(11) The results suggest that azapropazone can be given together with antacids and laxatives since there is no significant interaction.
(12) From this controlled double-blind study it is not possible to draw any definite conclusions regarding the efficacy of bulk laxatives on geriatric patients.
(13) Furthermore, these data demonstrate a previously unrecognised interaction between a commonly prescribed laxative--lactulose, and atenolol and hydrochlorothiazide.
(14) In total 90% of the women received drugs, excluding laxatives, oxytocics and long-term medication, vitamins and iron.
(15) Both types of abuse were associated with the following behaviors: running away; considering hurting oneself; suicide attempts; and the use of drugs, pot (marijuana), cigarettes, and laxatives.
(16) To evaluate these two laxative regimens the following parameters were monitored: quantity and quality of the feces and of additional laxatives used for regular defecation; acceptance by the patient; costs per patient and day.
(17) In the differential diagnosis of gastrointestinal disturbances the possibility of laxative abuse is considered either too late or not at all.
(18) Nor is there any difference between the two laxatives.
(19) It is noted that children who took more pills often had fewer or no symptoms, and that laxatives increased the incidence of vomiting.
(20) After adjusting for potential confounders (including age, sex, relevant medical conditions, health status, cognitive impairment, use of alcohol, depression and use of other medications), the following medications were found to be important risk factors for multiple falls: diazepam [odds ratio (OR): 3.7, 95% confidence interval (CI): 1.5-9.3], diltiazem (OR: 1.8, 95% CI: 0.8-4.1), diuretics (OR: 1.8, 95% CI: 1.2-2.8) and laxatives (OR: 2.1, 95% CI: 1.0-4.5).