(a.) Of enormous size; gigantic; huge; as, a colossal statue.
(a.) Of a size larger than heroic. See Heroic.
Example Sentences:
(1) "Businesses will be ecstatic at today's decision because the Games will bring a colossal one-off commercial boost to the entire country," said the group's president, Michael Cassidy.
(2) Mockingjay Part 1 may simply be suffering due to the huge success earlier this year of the latest Transformers movie, which made a colossal $301m in China .
(3) The Baltic nations, Ukraine and the countries of the southern Caucasus did not regain their independence until the final, colossal crash of the Soviet Union three years later.
(4) Still, the book, which was written by Blair himself rather than a ghostwriter and is scheduled for publication in September, has already earned him a colossal advance, said to be around £5m.
(5) The proposed rework was a “seriously retrograde step” – “a colossal mistake, and a dangerous one.” The opposition leader validated arguments Jewish groups, including the Executive Council of Australian Jewry, have raised this past week against the proposed RDA changes.
(6) Latest official figures seen by the Guardian, however, throw into sharp relief the colossal scale of the business, a back-office beehive of activity.
(7) The trio at the top – Lord Stevenson, the bank's chairman "from its birth to its death" and successive chief executives Sir James Crosby and Andy Hornby – were roundly blamed for the colossal failures that led to its collapse.
(8) For many City investors, however, these colossal payouts are not at all troubling.
(9) They punished aspiration by introducing tuition fees, saddled public services with long-term debt through the colossal rip-off of PFI, and began privatising our NHS – laying the foundations for some of the pernicious policies of this coalition as they did so.
(10) Former UN official accuses world body of 'colossal mismanagement' Read more While the UN provides shelter to about 200,000 people in their protection of civilians (POC) sites, the recent report is surely testament to the failure, at least in part, of this mandate, cataloguing horrific abuses against thousands of civilians.
(11) The colossal tarpaulin roof had actually been opened and closed regularly throughout the day, as if taunting those fans who could not attend the rescheduled game, as the locals sought to dry the surface so there was an irony this game kicked off with autumnal sunshine pouring through the concourse under the canopy.
(12) So for him to come along and lie to us and get that deep into our lives was a colossal, colossal betrayal."
(13) "It's a welcome decision but it also underscores what a colossal strategic blunder it was mov ing the News at Ten in the first place and allowing the BBC in to steal the slot."
(14) In their article, they argue: “The status quo is a colossal con perpetrated on the public by politicians who are too scared to break the taboo.” Portugal decriminalised all drugs at the turn of the century.
(15) Further investment would be required on the sections of route from Leamington Spa to Birmingham and between Leamington Spa and Coventry, but the cost of these improvements would be small change when set against the colossal bill for HS2.
(16) Unlike the colossal dead weight waste of giving winter fuel payments to the likes of me, EMA is tightly targeted.
(17) He has never dared refute the Institute for Fiscal Studies' predictions of 500,000 more children made poor as a direct result of his colossal £18bn benefit cuts.
(18) The west's inaction in the face of the pending Ba'athist and Shia Islamist victory amounts to a colossal failure of leadership.
(19) The vote was seen as vital for Greece to press ahead with austerity measures and avoid defaulting on its colossal €355bn (£297bn) debt.
(20) The war was either a colossal mistake or a struggle for important principles.
Profound
Definition:
(a.) Descending far below the surface; opening or reaching to a great depth; deep.
(a.) Intellectually deep; entering far into subjects; reaching to the bottom of a matter, or of a branch of learning; thorough; as, a profound investigation or treatise; a profound scholar; profound wisdom.
(a.) Characterized by intensity; deeply felt; pervading; overmastering; far-reaching; strongly impressed; as, a profound sleep.
(a.) Bending low, exhibiting or expressing deep humility; lowly; submissive; as, a profound bow.
(n.) The deep; the sea; the ocean.
(n.) An abyss.
(v. t.) To cause to sink deeply; to cause to dive or penetrate far down.
(v. i.) To dive deeply; to penetrate.
Example Sentences:
(1) With profound blockade, the slope of the edrophonium dose-response relationship was significantly flatter (P less than 0.05) than that of neostigmine.
(2) Cadavers have a multitude of possible uses--from the harvesting of organs, to medical education, to automotive safety testing--and yet their actual utilization arouses profound aversion no matter how altruistic and beneficial the motivation.
(3) Our positive experiences with IMACS discussed above should be even more profound and profitable for the larger medical institutions.
(4) This study compares the effects of 60 minutes of ischemic arrest with profound topical hypothermia (10 dogs) on myocardial (1) blood flow and distribution (microspheres), (2) metabolism (oxygen and lactate), (3) water content (wet to dry weights), (4) compliance (intraventricular balloon), and (5) performance (isovolumetric function curves) with 180 minutes of cardiopulmonary bypass with the heart in the beating empty state (seven dogs).
(5) About one out of three profoundly deaf children has an autosomal recessive form of inherited deafness.
(6) This continuing influence of Nazi medicine raises profound questions for the epistemology and morality of medicine.
(7) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(8) After a 2-day incubation with IL-4, expression of IL-2R p55 was markedly induced, but expression of IL2-R p70-75 was profoundly suppressed in a dose-dependent manner.
(9) "For those people who are able to use the laws, the change is profound."
(10) Most striking finding was his difficulty in identifying common objects and colours along with a profound alexia.
(11) This BOA technique was used to test the hearing of 82 profoundly involved handicapped children.
(12) These tools will allow us to manipulate the mammalian immune response in a variety of different ways that will have a profound impact both on our understanding of immunology and on medicine in the future.
(13) Based on the fact that all hibernators, at their regulated minimal body temperature, display a uniform turnover rate, related to body weight, the hypothesis is developed that cold tolerance of mammals is generally limited by a common specific minimal metabolic rate, which larger organisms, because of their lower basal metabolism, already attain in less profound hypothermia.
(14) Insulin-like growth factor II (IGF-II) is present at high levels in fetal and early neonatal rat plasma, and decreases profoundly following birth.
(15) The reduction in level of activity and adverse changes in body composition caused by SCI have profound metabolic consequences that may influence the progression and severity of coronary artery disease.
(16) The case of a 32-year-old man who suffered a blow to his left supraorbital region and eyebrow in an automatic closing door is reported to draw attention to the uncommon but trivial nature of this injury which may result in profound visual loss.
(17) In the paper life-threatening diseases which may be accompanied by profound unconsciousness are explained from the laboratory-chemical point of view.
(18) However pneumonia to PC points to a poor prognosis because they are always associated with a profound deficit or cellular immunity.
(19) Thus, it is possible that the loss of these dendritic cells may contribute to the profound immunological abnormalities seen in AIDS.
(20) They produce a more profound effect on clinical and biochemical aspects of rheumatoid arthritis than do the aspirin-like non steroidals.