(a.) Formed in columns; having the form of a column or columns; like the shaft of a column.
Example Sentences:
(1) In normal seminal vesicle, the reaction product was apparently more abundant in columnar and basal cells than in other cell types.
(2) The observed staining indicated that the epithelium of the external auditory meatus has a pattern of keratin expression typical of epidermis in general and the epithelium of the middle ear resembles simple columnar epithelia.
(3) Results of the present study show that epithelial cells of ciliated columnar type covering vocal cords change remarkably to nonciliated squamous cells between prenatal and postnatal stages.
(4) A monoclonal antibody specific for columnar epithelium (RGE 53) gave a positive reaction in endocervical columnar cells and in some immature metaplastic cells but was negative in subcolumnar reserve cells, squamous (metaplastic) cells, dysplastic cells, and most cases of carcinoma in situ.
(5) Histochemical and electron-microscopic observations on a 30-month-old child with Hurler syndrome showed marked irregularities in chondrocyte orientation within the growth plate, along with disruption of the normal columnar architecture.
(6) These patterns did not parallel the increase in microvillar height and number and basolateral interdigitations of the surface columnar cells, the structural correlates of lactase, and sodium-potassium-stimulated adenosine triphosphatase, respectively.
(7) There was no evidence of a "columnar" or "blob" pattern of any binding site within any of the laminae.
(8) The stratum superficiale consists during this phase of tall columnar cells.
(9) There was gradual regeneration of epithelium which showed slow maturation from flat non-ciliated epithelium to partially cuboidal and columnar epithelium with some cilia showing early differentiation to respiratory epithelium.
(10) The MNT was composed mainly of two cell types: small immature neuroblast-like cells and large columnar or cuboidal epithelial-like cells with or without melanin granules.
(11) The binding of 5 lectins (wheat germ, Dolichos bifluros, peanut, soybean, and Ulex europeus) was found to be independent of the stage of differentiation; "pre-differentiated" columnar cells which had prominent microvilli and no or few mucous secretory granules had identical staining patterns as well-differentiated goblet cells with large numbers of secretory granules.
(12) Photograph: Alamy The Devils Postpile, near Mammoth Lakes on the east side of Yosemite, looks as if it might have been created by some satanic sculptor, but really it's just one of the world's best examples of columnar basalt, a similar geological feature to the Giants Causeway in Northern Ireland.
(13) Barrett's esophagus is a condition in which the stratified squamous epithelium of the esophagus is replaced by metaplastic columnar epithelium that predisposes to the development of esophageal adenocarcinoma.
(14) There is a restructuring of the terminal vascular network of the pre-existing columnar epithelium in noninvasive cervical neoplasia which is caused by compression of the capillaries by the epithelial proliferation.
(15) Endometrial cells in suspension were stained with propidium iodide and a monoclonal antibody against a cytokeratin intermediate filament protein specific for glandular and columnar cells (RGE 53).
(16) The 9k-Da CaBP mRNA was observed mainly in the cytoplasm of the columnar cells and less frequently in the nucleus.
(17) Columnar epithelium in the nasal mucosa showed TK staining in all layers, KL1 staining on the apical side of epithelial cells and trace or negative staining in basal layer cells.
(18) There is no satisfactory biomarker yet available for predicting the likelihood of premalignant changes or carcinoma developing in Barrett's or columnar lined oesophagus.
(19) None of the control samples contained columnar cells and only 1 of 200 control samples contained metaplastic cells.
(20) The tumors were superficial, solitary masses consisting of cuboidal to columnar cells in tubuloglandular arrangement.
Subcolumnar
Definition:
(a.) Having an imperfect or interrupted columnar structure.
Example Sentences:
(1) A monoclonal antibody specific for columnar epithelium (RGE 53) gave a positive reaction in endocervical columnar cells and in some immature metaplastic cells but was negative in subcolumnar reserve cells, squamous (metaplastic) cells, dysplastic cells, and most cases of carcinoma in situ.
(2) SCUC probably arises either from basal cells of the cervical squamous epithelium, or gland cells of the endocervical epithelium, or still from subcolumnar endocervical reserve cells.
(3) Most cells in 13 examined squamous carcinomas revealed a cytokeratin phenotype detected in ectocervical basal cells and endocervical subcolumnar reserve cells: 8+, 14+, 18+, 19+, 4-, 10-, 13-.
(4) However, in the endocervix the protein detection was useful to follow the evolution of the subcolumnar cells to simple squamous metaplasia.
(5) This study favors an epithelial origin and a squamoid nature of subcolumnar reserve cells.
(6) Furthermore, there appear to be variants of pseudostratified columnar epithelium, i.e., the usual bronchial type lining the laryngeal ventricle, and a type with a thicker subcolumnar cell compartment that is found on the laryngeal surface of the epiglottis.
(7) In addition, subcolumnar basal cells actively synthesized RNA, reflecting their ability for further growth and development.
(8) Our studies reveal the presence of a relatively large number of vimentin-positive and T6-positive (Langerhans) cells in normal ectocervical stratified squamous epithelium, a small number in endocervical columnar epithelium, and a larger number in subcolumnar reserve cell hyperplasia and in immature squamous metaplasia.
(9) Autoradiographic investigations demonstrated that glandular cells and subcolumnar basal cells synthesize DNA in premenopausal and postmenopausal women.
(10) Expression of keratins 5, 14 and 17 in endocervical subcolumnar reserve cells was detected by means of immunohistochemical studies using polypeptide specific monoclonal antibodies.
(11) It is postulated that squamous cell carcinoma, adenocarcinoma, and mixed adenosquamous cell carcinoma of the uterine cervix all have a common cell or origin, the subcolumnar reserve cell.
(12) In cycling women the estrogen-responsive protein was identified in the subcolumnar cells of the endocervix, whereas in the ectocervix the protein was detected mainly in the parabasal and intermediate cell layers but alternating with unstained areas.
(13) These results support the hypothesis of an epithelial origin of reserve subcolumnar cells, and suggest that precocious squamous differentiation seems to take place in metaplastic cells of the human endocervix.
(14) We have analyzed the expression of cytokeratin polypeptides in subcolumnar reserve cells of the human uterine endocervical mucosa and the other epithelial cells using immunoperoxidase and immunofluorescence microscopy as well as by applying two-dimensional gel electrophoresis to microdissected cytoskeletal preparations.
(15) Using the double label indirect immunofluorescence technique we have studied vimentin-positive cells present in normal ecto- and endocervical epithelium, subcolumnar reserve cell hyperplasia, and squamous metaplastic and dysplastic epithelium of the uterine cervix.
(16) This finding is further evidence in support of the theory that glandular and squamous intraepithelial neoplasia in the cervix are closely related conditions, possibly with a common origin in the subcolumnar reserve cell.
(17) The new monoclonal antibody DE-K14, specific for cytokeratin 14, proved a specific marker of subcolumnar reserve cells in the endocervix.
(18) A positive reaction was also found in subcolumnar reserve cell hyperplasia, in squamous metaplastic and dysplastic cells, and in (squamous) carcinoma in situ.
(19) This study presents a detailed ultrastructural examination of the human endocervix with evidence for the differentiation of subcolumnar basal cells into mucus-secreting cells and ciliated columnar cells.
(20) Similarities in cytokeratin expression were found between dysplasia and carcinoma in situ on one hand and subcolumnar reserve cell hyperplasia and squamous metaplasia on the other.