(p. p. & a) Joined or held together; leagued; confederated.
(p. p. & a) Composed or made; -- with of.
(p. p. & a) Closely or firmly united, as the particles of solid bodies; firm; close; solid; dense.
(p. p. & a) Brief; close; pithy; not diffuse; not verbose; as, a compact discourse.
(v. t.) To thrust, drive, or press closely together; to join firmly; to consolidate; to make close; -- as the parts which compose a body.
(v. t.) To unite or connect firmly, as in a system.
(n.) An agreement between parties; a covenant or contract.
Example Sentences:
(1) The estimated DNA compaction ratio (approximately 3-fold) is consistent with a significant degree of nucleosome unfolding in the hyperstimulated BR genes.
(2) DNA compactization by protamines and histones HI is discussed in terms of the results obtained.
(3) At S-L clefts, paranodal-nodal regions, and Schwann cell nuclei, the axonal areas were smaller and the NF densities were higher than at compact myelinated regions.
(4) A compact attachment for microscope-type instruments is described enabling to introduce, rapidly and qualitatively, minute biological speciments into melted embedding medium and ensuring the safety of optics.
(5) Laminin was already present on the cell surface at the 2-cell stage, while nidogen was first detectable on compacted 8- to 16-cell stage morulae.
(6) Both types of molecules are compact and globular in shape and apparently contain beta-pleated sheet conformation.
(7) The tail region appeared to be cleaved off, making the head region less compact.
(8) Qualitatively the cell aspirator collected epithelial cells which were better preserved morphologically, but also a larger number of compact cell clusters.
(9) The ultrastructural study of nucleoli and ribonucleoprotein-containing structures in human seminiferous tubules revealed that the nucleoli of spermatogonia, spermatocytes and Sertoli cells exhibited a tripartite structure consisting of: a fibrillar center, a compact granular portion, and a reticular portion containing both pars fibrosa and pars granulosa.
(10) Compaction of the morula is a prerequisite for subsequent differentiation of the mouse embryo.
(11) Most double-helical segments were reactive to cobra venom ribonuclease to some degree; the exceptions were the five "long-range" helices that are probably compactly folded within the structure.
(12) During powder compaction on a Manesty Betapress, peak pressures, Pmax, are reached before the punches are vertically aligned with the centres of the upper and lower compression roll support pins.
(13) Based on these results we propose that the linearization of the DNA elution dose-response curve observed after chromatin decondensation reflects a reduction in the degree of chromatin compactness in the nuclear complexes that leads to a relatively uniform distribution of the DNA on the filter and reduces trapping of elutable material in the compact nuclear structures otherwise present.
(14) Cleavage to the compacted and cavitating stages was achieved in 78% and 69%, respectively, of human embryos cocultured in 24-48 hour human ampullary subcultures as compared to 50% and 33%, respectively, for embryos grown in culture medium alone.
(15) These observations strongly suggest that (i) GCN4 specifically recognizes the central base pair, (ii) the optimal half-site for GCN4 binding is ATGAC, not ATGAG, and (iii) GCN4 is a surprisingly flexible protein that can accommodate the insertion of a single base pair in the center of its compact binding site.
(16) In fact, the large scattering angle we chose, theta = 135 degrees, allowed us to assemble a very compact source-detector device.
(17) A monoclonal antibody to the cell adhesion molecule, E-cadherin, which mediates mouse embryo compaction, completely blocks compaction induced by these activators of PKC.
(18) At rostral levels, one third of the tracts are loosely built forming a king of curtain, while they become more compact at caudal levels.
(19) This shows that the compaction of chromatin associated with transcriptional inactivation does not require phosphorylation of H3 and suggests that the level of basal phosphorylation of H1 is not correlated with the intensity of transcription or DNA replication.
(20) After 8 days of incubation, SM subdivides into superficial (compact) and deep (disperse) sublaminae.
Crush
Definition:
(v. t.) To press or bruise between two hard bodies; to squeeze, so as to destroy the natural shape or integrity of the parts, or to force together into a mass; as, to crush grapes.
(v. t.) To reduce to fine particles by pounding or grinding; to comminute; as, to crush quartz.
(v. t.) To overwhelm by pressure or weight; to beat or force down, as by an incumbent weight.
(v. t.) To oppress or burden grievously.
(v. t.) To overcome completely; to subdue totally.
(v. i.) To be or become broken down or in, or pressed into a smaller compass, by external weight or force; as, an eggshell crushes easily.
(n.) A violent collision or compression; a crash; destruction; ruin.
(n.) Violent pressure, as of a crowd; a crowd which produced uncomfortable pressure; as, a crush at a peception.
Example Sentences:
(1) The number of axons displaying peptide-like immunoreactivity within the optic nerve, retinal or cerebral to the crush, and within the optic chiasm gradually decreased after 2-3 months.
(2) Crushing their dream of denying healthcare to millions of people will put them on that road to despair.
(3) Reality set in once you got home to your parents and the regular neighborhood kids, and your thoughts turned to new notebooks for the school year and whether you got prettier while you were away and whether your crushes were going to notice.
(4) The wide variation in potency explains the variation found in absolute bioavailability, and the increase in release rate when the pellets are crushed explains the differences seen in peak plasma times, since the pellets will be chewed to varying degrees by the horse.
(5) In case 2, a 26-year-old man sustained an open total dislocation of the talus with a severe crush wound and impaired circulation to the foot.
(6) "Everyone has been blasted by anonymous figures who crushed the economy.
(7) The main objective of these experiments was to develop and characterize a new experimental model of venous thrombosis, and determine whether a combination of vascular wall damage (crushing with hemostat clamps) and prolonged stasis produced more reproducible clots than prolonged stasis per se.
(8) Despite a glorious career, her Olympic history had been one of crushing disappointment.
(9) In one group of rats, the RGC proteins were labeled 1 week after crushing.
(10) In adrenergic axons NA, DBH-IR and TH-IR accumulated with time after crushing the nerve as described earlier with biochemical techniques.
(11) This is the first reported case, to the best of my knowledge, of disk neovascularization occurring after intravenously injected, crushed, unfiltered, methylphenidate HCl tablets.
(12) An epidemic of abuse with "T's and blues" began in the late 1970's in which pentazocine-Talwin tablets ("T")--and the antihistamine tripelennamine (known as blues) were crushed, dissolved together, filtered, and injected intravenously.
(13) Labeled axons were first detected in the segment of optic nerve lying distal to the crush site 1 week after injury and had extended as far as 2.3 mm beyond the crush site by 60 days postinjury, growing at a rate similar to that at which the collateral branches of developing ganglion cell axons extend into their targets.
(14) On 21 August 1968, armies of five Warsaw Pact countries – the Soviet Union, Poland, Hungary, Bulgaria and East Germany – invaded Czechoslovakia to crush democratic reforms known as the Prague spring.
(15) Freeze-dried crushed cortical bone allografts were implanted into widemouthed three-wall, two-wall, one-wall, combination, and furcation defects.
(16) Previous work from our laboratory had shown that goldfish retinal fragments explanted onto a polylysine substratum 1 to 2 weeks following optic nerve crush exhibit a striking clockwise pattern of neuritic outgrowth.
(17) Thus did Dominic Cummings, former special adviser to Michael Gove , deliver to his prime minister what is, in certain Tory circles, the most crushing of insults.
(18) Isis recently threatened to kill American hostages to avenge the crushing airstrikes in Iraq against militants advancing on Mount Sinjar and the Kurdish capital of Irbil.
(19) Addictive onion consumption was prevented by mixing chopped or crushed onions in a total balanced ration.
(20) On a turnout of 50.78%, Labour's shellshocked candidate Imran Hussain was crushed by a 36.59% swing from Labour to Respect that saw Galloway take the seat with a majority of 10,140.