(n.) Composed of two or more parts; composite; not simple; as, a complex being; a complex idea.
(n.) Involving many parts; complicated; intricate.
(n.) Assemblage of related things; collection; complication.
Example Sentences:
(1) All mutant proteins could associate with troponin I and troponin T to form a troponin complex.
(2) Cellulase regulation appears to depend upon a complex relationship involving catabolite repression, inhibition, and induction.
(3) In addition, intravenous injection of complexes into rabbits showed optimal myocardial images with agents of intermediate lipophilicity.
(4) The various evocational changes appear to form sets of interconnected systems and this complex network seems to embody some plasticity since it has been possible to suppress experimentally some of the most universal evocational events or alter their temporal order without impairing evocation itself.
(5) The half-life of 45Ca in the various calcium fractions of both types of bone was 72 hours in both the control and malnourished groups except the calcium complex portion of the long bone of the control group, which was about 100 hours.
(6) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(7) It has recently been suggested that procaine penicillin existed in solution in vitro and in vivo as a "procaine - penicillin" complex rather than as dissociated ions.
(8) It involves creativity, understanding of art form and the ability to improvise in the highly complex environment of a care setting.” David Cameron has boosted dementia awareness but more needs to be done Read more She warns: “To effect a cultural change in dementia care requires a change of thinking … this approach is complex and intricate, and can change cultural attitudes by regarding the arts as central to everyday life of the care home.” Another participant, Mary*, a former teacher who had been bedridden for a year, read plays with the reminiscence arts practitioner.
(9) These membrane perturbation effects not observed with bleomycin-iron in the presence of a hydroxyl radical scavenger, dimethyl thiourea, or a chelating agent, desferrioxamine, were correlated with the ability of the complex to generate highly reactive oxygen species.
(10) The peak molecular weight never reached that of a complete 2:1 complex.
(11) Similar to intact crayfish, animals with an isolated protocerebrum-eyestalk complex, exhibit competent circadian rhythms in the electroretinogram (ERG).
(12) In the second approach, attachment sites of DTPA groups were directed away from the active region of the molecule by having fragment E1,2 bound in complex, with its active sites protected during the derivatization.
(13) An initial complex-soma inflection was observed on the rising phase of the action potential of some cells.
(14) Electron spin resonance studies indicate the formation of two vanadyl complexes that are 1:1 in vanadyl and deferoxamine, but have two or three bound hydroxamate groups.
(15) A complex linkage between the cytoskeleton and the extracellular matrix is illustrated both in the cord forming Sertoli and granulosa cells, and in the adjacent mesenchymal cells.
(16) When the eye was dissected into anterior uveal, scleral, and retinal complexes, prostaglandin D2 was formed in the highest degree in all the complexes, whereas prostaglandin E2 and F2 alpha formation was specific to given ocular regions.
(17) The possibility that both IL 2 production and IL 2R expression are autonomously activated early in T cell development, before acquisition of the CD3-TcR complex, led us to study the implication of alternative pathways of activation at this ontogenic stage.
(18) The disassembly of the synthetase complex is consistent with the structural model of a heterotypic multienzyme complex and suggests that the complex formation is due to the specific intermolecular interactions among the synthetases.
(19) The differential diagnosis is more complex in Hawaii due to the presence of granulomatous diseases such as tuberculosis and leprosy.
(20) Therapeutic possibilities for hepatogenous anaemia of complex genesis are discussed.
Hesperetin
Definition:
(n.) A white, crystalline substance having a sweetish taste, obtained by the decomposition of hesperidin, and regarded as a complex derivative of caffeic acid.
Example Sentences:
(1) Particularly, MC- and BNF-inducible P-450 showed high stereoselectivity on C6-position of testosterone, and PB-, flavone- and hesperetin-inducible one showed that on C2-position of this compound, respectively.
(2) Comparative examinations and autoxidation studies with the flavanon glycosides hesperidin and naringin as well as with their aglycones hesperetin and naringenin showed that the former are mainly responsible for the antioxidative activity of the citrus peel and extracts.
(3) Blood lipid levels in rats with hyperlipidemia resulting from high-fat feeding were determined after ip administration of an MeOH extract of Prunus davidiana stems and its flavonoid components, (+)-catechin, prunin (= naringenin 7-O-glucoside), and hesperetin 5-O-glucoside.
(4) The effect of several naturally occurring dietary flavonoids including quercetin, naringin, hesperetin, and catechin on the infectivity and replication of herpes simplex virus type 1 (HSV-1), polio-virus type 1, parainfluenza virus type 3 (Pf-3), and respiratory syncytial virus (RSV) was studied in vitro in cell culture monolayers employing the technique of viral plaque reduction.
(5) This glucosyltransferase has an expressed specificity for the 7-position of the flavanones naringenin (Kmapp 62 microM; Kmapp UDPG 51 microM) and hesperetin (Kmapp 124 microM; Kmapp UDPG 243 microM) and did not accept other flavone or flavonol aglycones.
(6) A time-course study indicated that hesperetin was able to delay the lipolytic action of epinephrine.
(7) Of the compounds tested (naringin, rutin, neohesperetin, hesperetin, dihydroquercetin, quercetin, quercetin pentaacetate, permethylquercetin, m-hydroxyphenylacetic acid, and m,p-dihydroxyphenylacetic acid), only quercetin was mutagenic without microsomal activation.
(8) Trypsin-activated phosphorylase kinase was inhibited by quercetin and stimulated by hesperetin, as for the native enzyme.
(9) Prunin and hesperetin 5-O-glucoside did not show such an effect in high-fat-fed hypertriglyceridemic rats, but they did exhibit a significant hypocholesterolemic effect.
(10) The Km for UDP-rhamnose was similar with prunin (1.3 microM) and hesperetin-7-O-glucoside (1.1 microM) as substrate.
(11) The other flavonoids studied, viz., quercetin, quercetrin, rutin, taxifolin, myricetin, myricetrin, phloretin, phloridzin, diosmetin, diosmin, apiin, hesperetin, naringenin, (+)-catechin, morin, fisetin, chrysin, and 3-hydroxyflavone, all showed varying extents of inhibition of the nonenzymatic lipid peroxidation, induced by either ascorbic acid or ferrous sulfate.
(12) The X-ray crystal structure analysis of hesperetin monohydrate showed that the molecule is essentially planar despite the sofa conformation of the gamma-pyran ring and the 27 degrees twist of the 2-phenyl ring.
(13) Flavone- and hesperetin-inducible P-450 catalyzed the hydroxylation of testosterone more effectively than other chemicals-inducible ones.
(14) The enzyme catalyzes the transfer of rhamnose from UDP-rhamnose to the C-2 hydroxyl group of glucose attached via C-7-O- of naringenin or hesperetin.
(15) Of the fifteen flavonoids studied, fisetin, quercetin and luteolin were the most potent, while hesperetin, taxifolin and rutin were among the least potent.
(16) Only butein and hesperetin showed inhibition of epinephrine-induced lipolysis, and their effect was dose-dependent.
(17) From 14 flavonoids tested, the flavones quercetin and fisetin were found to be efficient inhibitors of nonactivated phosphorylase kinase when assayed at pH 8.2, causing 50% inhibition at a concentration of about 50 microM, while the flavanone hesperetin stimulated phosphorylase kinase activity about 2-fold when tested at 250 microM.
(18) The affinity for the natural acceptor prunin (Km = 2.4 microM) was much higher than for hesperetin-7-O-glucoside (Km = 41.5 microM).
(19) Transcription of rhiA is repressed in cells grown in the presence of the flavanone hesperetin or the flavone apigenin, both of which are potent inducers of transcription of nod genes.
(20) Two other flavonoids tested, i.e., rutin (3-rhamnosylglucoside of quercetin) and hesperidin [7-b rutinoside of hesperetin (3'-5-3-hydroxy-4-methoxyflavone)] were ineffective both alone and in combination with CDDP.