(n.) In the East Indies, an inclosure containing a house, outbuildings, etc.
(v. t.) To form or make by combining different elements, ingredients, or parts; as, to compound a medicine.
(v. t.) To put together, as elements, ingredients, or parts, in order to form a whole; to combine, mix, or unite.
(v. t.) To modify or change by combination with some other thing or part; to mingle with something else.
(v. t.) To compose; to constitute.
(v. t.) To settle amicably; to adjust by agreement; to compromise; to discharge from obligation upon terms different from those which were stipulated; as, to compound a debt.
(v. i.) To effect a composition; to come to terms of agreement; to agree; to settle by a compromise; -- usually followed by with before the person participating, and for before the thing compounded or the consideration.
(v. t.) Composed of two or more elements, ingredients, parts; produced by the union of several ingredients, parts, or things; composite; as, a compound word.
(n.) That which is compounded or formed by the union or mixture of elements ingredients, or parts; a combination of simples; a compound word; the result of composition.
(n.) A union of two or more ingredients in definite proportions by weight, so combined as to form a distinct substance; as, water is a compound of oxygen and hydrogen.
Example Sentences:
(1) These factors might account for the lower systemic bioavailability of these compounds.
(2) The interaction of the antibody with both the bacterial and the tissue derived polysialic acids suggests that the conformational epitope critical for the interaction is formed by both classes of compounds.
(3) These organic compounds were found to be stable on the sorbent tubes for at least seven days.
(4) Compound Z has the properties expected of an oxidized MPT precursor.
(5) Although Jeggo's Chinese hamster ovary cells were more responsive to mAMSA, novo still abrogated mAMSA toxicity in the mutant cells as well as in the parental Chinese hamster ovary cells 2,4-Dinitrophenol acted similarly to novo with respect to mAMSA killing, but neither compound reduced the ATP content of V79 cells.
(6) Recent data collected by the Games Outcomes Project and shared on the website Gamasutra backs up the view that crunch compounds these problems rather than solving them.
(7) There fore, the adverse effects may be induced by such quartz or silicon compounds.
(8) Fluorination with [18F]acetylhypofluorite yields 6-[18F]fluoro-L-dopa with 95% radiochemical purity; fluorination of the same substrate with [18F]F2 yields a mixture of all three structural isomers in a ratio of 70:16:14 for 6-, 5-, and 2-fluoro compounds.
(9) Mitonafide is the lead compound of a new series of antitumor drugs, the 3-Nitronaphthalimides, which have shown antineoplastic activity in vitro as well as in vivo.
(10) We have examined the activities of X, Y, and several related compounds as activators of macrophages.
(11) [125I]ET-1 binding to ETB receptors (nonselective to ET isopeptides) in cerebellar membranes was not inhibited by either of these compounds even at 100 microM.
(12) The individual classes of drugs are first treated separately to highlight specific aspects of their quantification, and this is followed by an overview of those methods permitting the concomitant analysis of two or more antiepileptic compounds.
(13) The remainder of the radioactivity appeared chromatographically just prior to the bisantrene peak, indicating that compounds more polar than the parent were present as transformation products.
(14) The ADAM derivative of carnitine was separated from decomposition products of the reagent and related compounds such as amino acid derivatives on a silica gel column eluted with methanol-5% aqueous SDS-phosphoric acid (990:10:1).
(15) Accidentally discovered nearly 40 years ago as the first true antidepressants, the MAOIs soon fell into disfavor due to concerns about toxicity and seemingly lesser efficacy compared with the newer tricyclic compounds.
(16) In a series of compounds with H2-antihistaminic activity, a conformational analysis was performed based on force field calculations.
(17) All three compounds were also very similar in their effects on [3H]5HT release from superfused rat striatal slices.
(18) A new compound, 5-bromo-2-(N,N-dimethylaminomethyl)furnan (IIc), is prepared in a similar way.
(19) On the basis of obtained data on the uniformity of chemical compounds of the secretion of glands belonging to different groups their common origin has been suggested.
(20) S-methyl-l-cysteine, 2-hydroxy-4-methiol butyric acid, S-adenosyl-l-methionine, and methionine peptides were the only compounds supporting growth, when substituted for methionine.
Coumarin
Definition:
(n.) The concrete essence of the tonka bean, the fruit of Dipterix (formerly Coumarouna) odorata and consisting essentially of coumarin proper, which is a white crystalline substance, C9H6O2, of vanilla-like odor, regarded as an anhydride of coumaric acid, and used in flavoring. Coumarin in also made artificially.
Example Sentences:
(1) A phytochemical investigation of an ethanolic extract of the whole plant of Echites hirsuta (Apocynaceae) resulted in the isolation and identification of the flavonoids naringenin, aromadendrin (dihydrokaempferol), and kaempferol; the coumarin fraxetin; the triterpene ursolic acid; and the sterol glycoside sitosteryl glucoside.
(2) Among them, the coumarins, rutins, Centella asiatica extracts, procyanoside oligomers are the most prescribed.
(3) This novel coumarin derivative significantly inhibited skin tumor initiation by DMBA in SENCAR mice when given at a dose of 200 nmol, 5 min (69% inhibition) or 24 h (76% inhibition) prior to initiation.
(4) The aflatoxins are a family of complex coumarins produced by species of Aspergillus that are toxic and carcinogenic in animals.
(5) Coumarin and 7-HCG are best fitted to an open two-compartment model, whereas 7-HC is best fitted to an open one-compartment model.
(6) Drug interactions with coumarin anticoagulants and sulphonylurea compounds may produce bleeding episodes and hypoglycaemia, respectively.
(7) Neither macroscopic nor microscopic examination of liver tissue revealed any pathological alterations caused by coumarin.
(8) 10 coumarins used in perfumery, cosmetics and ointments, have been investigated by 2 different methods to determine their sensitizing capacity.
(9) Coumarin-induced hepatotoxicity was associated with significant increases in relative liver weight, plasma alanine and aspartate aminotransferase activities and hepatic non-protein sulphydryl groups.
(10) Treatment of isolated canine renal Na,K-ATPase with a stable diazomethane analog, 4-(diazomethyl)-7-(diethylamino)-coumarin (DEAC), results in enzyme inactivation.
(11) Among the non-infectious agents alcohol is the most important, followed by a combination of anticonvulsant drugs, valproic acid, retinoic acid, lithium, coumarin derivates, methyl mercury, aminopterin and methotrexate, cocaine and amniogenic bands.
(12) The results demonstrate a reserve capacity for the coumarin-sensitive reductase; at least 70% of the hepatic vitamin K1 2,3-epoxide reductase activity has to be eliminated before the vitamin K-dependent carboxylation of the clotting factors objectively becomes compromised.
(13) Coumarin and cimetidine appear to be safe and active agents in the treatment of metastatic renal carcinoma.
(14) This correlated well with the suppression by coumarin of the dextran-induced leucocyte response in vivo.
(15) In three patients painful reddening of a well-circumscribed area of the skin occurred within five days of starting anticoagulant treatment with phenprocoumon (Marcumar), and within a short time it developed into a full-blown picture of coumarin necrosis.
(16) A 2-7-fold increase in response to the inducers was seen in the amount of P-450Coh (cytochrome P-450 isoenzyme catalysing coumarin 7-hydroxylation) protein in Western immunoblots.
(17) These findings suggest that the coumarin ring system is largely responsible for the pharmacodynamic properties of warfarin, whereas the side-chain dictates the disposition and metabolism of the drug.
(18) The latter effect was effectively suppressed by a concomitant administration of a combination of troxerutin and coumarin (Venalot).
(19) A substantial improvement in the rate of detection of organic lesions affecting the olfactory pathway can be achieved by substituting odours such as musk ketone, exaltolide, linalyl acetate and coumarin for those in current use.
(20) Coumarin concentrations that inhibited growth of Pythium sp.