What's the difference between compound and derivative?

Compound


Definition:

  • (n.) In the East Indies, an inclosure containing a house, outbuildings, etc.
  • (v. t.) To form or make by combining different elements, ingredients, or parts; as, to compound a medicine.
  • (v. t.) To put together, as elements, ingredients, or parts, in order to form a whole; to combine, mix, or unite.
  • (v. t.) To modify or change by combination with some other thing or part; to mingle with something else.
  • (v. t.) To compose; to constitute.
  • (v. t.) To settle amicably; to adjust by agreement; to compromise; to discharge from obligation upon terms different from those which were stipulated; as, to compound a debt.
  • (v. i.) To effect a composition; to come to terms of agreement; to agree; to settle by a compromise; -- usually followed by with before the person participating, and for before the thing compounded or the consideration.
  • (v. t.) Composed of two or more elements, ingredients, parts; produced by the union of several ingredients, parts, or things; composite; as, a compound word.
  • (n.) That which is compounded or formed by the union or mixture of elements ingredients, or parts; a combination of simples; a compound word; the result of composition.
  • (n.) A union of two or more ingredients in definite proportions by weight, so combined as to form a distinct substance; as, water is a compound of oxygen and hydrogen.

Example Sentences:

  • (1) These factors might account for the lower systemic bioavailability of these compounds.
  • (2) The interaction of the antibody with both the bacterial and the tissue derived polysialic acids suggests that the conformational epitope critical for the interaction is formed by both classes of compounds.
  • (3) These organic compounds were found to be stable on the sorbent tubes for at least seven days.
  • (4) Compound Z has the properties expected of an oxidized MPT precursor.
  • (5) Although Jeggo's Chinese hamster ovary cells were more responsive to mAMSA, novo still abrogated mAMSA toxicity in the mutant cells as well as in the parental Chinese hamster ovary cells 2,4-Dinitrophenol acted similarly to novo with respect to mAMSA killing, but neither compound reduced the ATP content of V79 cells.
  • (6) Recent data collected by the Games Outcomes Project and shared on the website Gamasutra backs up the view that crunch compounds these problems rather than solving them.
  • (7) There fore, the adverse effects may be induced by such quartz or silicon compounds.
  • (8) Fluorination with [18F]acetylhypofluorite yields 6-[18F]fluoro-L-dopa with 95% radiochemical purity; fluorination of the same substrate with [18F]F2 yields a mixture of all three structural isomers in a ratio of 70:16:14 for 6-, 5-, and 2-fluoro compounds.
  • (9) Mitonafide is the lead compound of a new series of antitumor drugs, the 3-Nitronaphthalimides, which have shown antineoplastic activity in vitro as well as in vivo.
  • (10) We have examined the activities of X, Y, and several related compounds as activators of macrophages.
  • (11) [125I]ET-1 binding to ETB receptors (nonselective to ET isopeptides) in cerebellar membranes was not inhibited by either of these compounds even at 100 microM.
  • (12) The individual classes of drugs are first treated separately to highlight specific aspects of their quantification, and this is followed by an overview of those methods permitting the concomitant analysis of two or more antiepileptic compounds.
  • (13) The remainder of the radioactivity appeared chromatographically just prior to the bisantrene peak, indicating that compounds more polar than the parent were present as transformation products.
  • (14) The ADAM derivative of carnitine was separated from decomposition products of the reagent and related compounds such as amino acid derivatives on a silica gel column eluted with methanol-5% aqueous SDS-phosphoric acid (990:10:1).
  • (15) Accidentally discovered nearly 40 years ago as the first true antidepressants, the MAOIs soon fell into disfavor due to concerns about toxicity and seemingly lesser efficacy compared with the newer tricyclic compounds.
  • (16) In a series of compounds with H2-antihistaminic activity, a conformational analysis was performed based on force field calculations.
  • (17) All three compounds were also very similar in their effects on [3H]5HT release from superfused rat striatal slices.
  • (18) A new compound, 5-bromo-2-(N,N-dimethylaminomethyl)furnan (IIc), is prepared in a similar way.
  • (19) On the basis of obtained data on the uniformity of chemical compounds of the secretion of glands belonging to different groups their common origin has been suggested.
  • (20) S-methyl-l-cysteine, 2-hydroxy-4-methiol butyric acid, S-adenosyl-l-methionine, and methionine peptides were the only compounds supporting growth, when substituted for methionine.

Derivative


Definition:

  • (a.) Obtained by derivation; derived; not radical, original, or fundamental; originating, deduced, or formed from something else; secondary; as, a derivative conveyance; a derivative word.
  • (n.) That which is derived; anything obtained or deduced from another.
  • (n.) A word formed from another word, by a prefix or suffix, an internal modification, or some other change; a word which takes its origin from a root.
  • (n.) A chord, not fundamental, but obtained from another by inversion; or, vice versa, a ground tone or root implied in its harmonics in an actual chord.
  • (n.) An agent which is adapted to produce a derivation (in the medical sense).
  • (n.) A derived function; a function obtained from a given function by a certain algebraic process.
  • (n.) A substance so related to another substance by modification or partial substitution as to be regarded as derived from it; thus, the amido compounds are derivatives of ammonia, and the hydrocarbons are derivatives of methane, benzene, etc.

Example Sentences:

  • (1) The interaction of the antibody with both the bacterial and the tissue derived polysialic acids suggests that the conformational epitope critical for the interaction is formed by both classes of compounds.
  • (2) The vascular endothelium is capable of regulating tissue perfusion by the release of endothelium-derived relaxing factor to modulate vasomotor tone of the resistance vasculature.
  • (3) Leumorphin is a 29-amino-acid peptide derived from preproenkephalin B. Intracerebroventricular (i.c.v.)
  • (4) A full-length cDNA encoding porcine heart aconitase was derived from lambda gt10 recombinant clones and by amplification of the 5' end of the mRNA.
  • (5) In animal experiments pharmacological properties of the low molecular weight heparin derivative CY 216 were determined.
  • (6) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
  • (7) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
  • (8) PMNs could be primed for PMA-triggered oxidative burst by muramyl peptide molecules (MDP) and two of its adjuvant active nonpyrogenic derivatives.
  • (9) Recent studies have shown that an aberration in platelet-derived growth factor gene expression is unlikely to be a factor in proliferation of smooth-muscle cells.
  • (10) The macrophage-derived product, interleukin 1 (IL 1) is thought to play an important regulatory role in the proliferation of T lymphocytes; however, its mechanism of action is unknown.
  • (11) In the upper limb and facial forms of familial amyloidotic polyneuropathy first recorded in Swiss and Finns respectively, the differences in their patterns of neurological disease and ocular lesions could be the result of their amyloids deriving from proteins other than prealbumin.
  • (12) The antiproliferative activity of IFN was studied using the parental L cell line, a tk- derivative, and a tk- (tk+) subline into which the tk gene of herpes simplex virus was introduced.
  • (13) Bipolar derivations with the maximum PSE always included the locations with the maximum PSE obtained from a linked ears reference.
  • (14) Only those derivatives with a free amino group and net positive charge in the side chain were effective.
  • (15) Northern blot analysis with an 18-mer radiolabelled oligonucleotide, derived from an ALP specific cDNA clone, revealed a specific mRNA of about 700-800 nucleotides in HS-24 tumor cells.
  • (16) The mortality data were derived from the reports by Miyagi Prefectural Government.
  • (17) Ferrocene derivatives, in general, show a degree of versatility, coupling the electron-transfer reactions of many enzymes.
  • (18) The ADAM derivative of carnitine was separated from decomposition products of the reagent and related compounds such as amino acid derivatives on a silica gel column eluted with methanol-5% aqueous SDS-phosphoric acid (990:10:1).
  • (19) This doxorubicin derivative did not bind to Sepharose which was conjugated with cardiac actin.
  • (20) In the triploids, the 40 female chromosomes present (mouse, n = 20) were derived from a single diploid pronucleus formed after the extrusion of a first polar body, and following the monospermic fertilization of primary oocytes.