(adv.) Against the affirmative side; in opposition; on the negative side; -- The antithesis of pro, and usually in connection with it. See Pro.
(v. t.) To know; to understand; to acknowledge.
(v. t.) To study in order to know; to peruse; to learn; to commit to memory; to regard studiously.
(v. t.) To conduct, or superintend the steering of (a vessel); to watch the course of (a vessel) and direct the helmsman how to steer.
Example Sentences:
(1) From these results it was concluded that FITC-Con A staining method applied to smear specimens is more advantageous in the rapidity and the simplicity for tumor cell diagnosis than section specimen method.
(2) The epithelium of Brunner's gland stained intensely with Ricinus communis agglutinin-I (RCA-I), succinylated-WGA (S-WGA) and wheat-germ agglutinin (WGA), moderately with Bandeirea simplicifolia agglutinin-I (BS-I), Concanavalia ensiformis agglutinin (Con A) peanut agglutinin (PNA) and Ulex europaeus agglutinin-I (UEA-I) and occasionally with Dolichos biflorus agglutinin (DBA), Lens culinaris agglutinin (LCA) and soybean agglutinin (SBA).
(3) After immunoadsorbent purification, the final step in a purification procedure similar to that adopted for colon cancer CEA, two main molecular species were identified: 1) Material identical with colon cancer CEA with respect to molecular size, PCA solubility, ability to bind to Con A, and most important the ability to bind to specific monkey anti-CEA serum.
(4) A significant decrease in response to two mitogens (PHA, Con-A) was seen in tumor-bearing rats concomitantly with the tumor growth.
(5) Concanavalin A (con A) is a potent inhibitor of coagulant activity of native tissue factor.
(6) The epidermal glycoproteins were probed with the lectin, concanavalin A (Con A).
(7) Furthermore, exogenous IL-1, IL-2, IL-4, interferon-gamma, or a rat Con A supernatant failed to abrogate DFMO inhibition.
(8) Besides various skin tests with the antigens candida, trichophyton, mumps, streptokinase-streptodornase, tuberculin, DNCB and KLH also in vitro experiments measuring the immunoglobulin- and complement concentrations, the antibody production to KLH, the lymphocyte transformation rate to PHA, Pokeweed, Con A, PPD were done nearly in all patients.
(9) However, the Con A-sup stimulates synergistically M-1 cells with DF.
(10) In one series of trials, spleen cells from strains of chickens with differing levels of susceptibility to MD tumors were stimulated with graded doses of Concanavalin A (Con A) or phytohemagglutin (PHA).
(11) When spleen cells were further cultured in vitro for 5 days in the presence of Concanavalin-A stimulated rat spleen cell supernatant (Con-A factor), CD4 or CD8 positive cells were detected in the VV (IL-6) injected group, while few positive cells were detected in the control groups.
(12) Make Quinn stay with B613 I think it would be difficult to bring her back to the fold at Pope and Associates (unless they’re playing the long con and her infiltration of B613 is part of the plan), but her anger would be well utilized against her former coworkers.
(13) The mitogenic responses to phytohemagglutinin (PHA) and concanavalin A (Con A), but not pokeweed mitogen (PWM), were decreased significantly in cultures with isolated lymphocytes, while in whole blood cultures the responses to PHA and PWM but not to Con A were reduced.
(14) A polypeptide of about 150 kDa appeared as the main Con A binding protein.
(15) Would I be stupid not to wait another six months or so, to get a 90% mortgage given the cons of Help to Buy?
(16) IL-2 gene transcripts were hardly detected after Con A activation of spleen cells from LCMV-infected mice.
(17) Thirty-eight female Wistar rats were randomly assigned to one of three groups: run-trained (RUN), swim-trained (SWIM) or control (CON).
(18) Lymphocyte blastogenesis in hairless descendants of Mexican hairless dogs was examined using the following mitogens: phytohemagglutinin (PHA-M), Concanavalin A (Con A), lipopolysaccharide (LPS) and pokeweed mitogen (PWM).
(19) Neither WGA nor concanavalin A (Con A) significantly affected basal 3H-thymidine incorporation.
(20) The increase in Con A fiber-binding seems to be specific for EGF, since it was not observed in response to insulin, prostaglandin F2alpha or a higher serum concentration, which also initiate cell devision of confluent quiescent 3T3 cells.
Kon
Definition:
(v. t.) To know. See Can, and Con.
Example Sentences:
(1) Plots of the observed rate constant for [3H]-QMDP-receptor complex formation, kon, versus [3H-QMDP] were linear at both 30 degrees C and 10 degrees C, consistent with the interaction of [3H]-QMDP with the H1-receptor being a simple, one-step equilibrium.
(2) The time course of the binding of a radioligand in the presence of a competing unlabeled ligand was analyzed in terms of rate constants of association (kon) and dissociation (koff) for binding of the radioligand and the competitor.
(3) The tension of the tonic response to Carb was unaffected by cooling and was only inhibited by nifedipine at 0.3 microM Carb at 37 degrees C. Both cooling and nifedipine, at 37 degrees C, decreased the rate constant of onset of the tonic response (kon) to Carb.
(4) Baboon elastase, however, is as effectively blocked with Eglin c (kon = 2.5 x 10(7) M-1s-1) as human elastase.
(5) Analysis of the kinetics of [125I- Tyr11]SRIF binding showed that the rate constant for association (kon = 1.7 x 10(8) M-8min-1) was similar to that for [125I-Tyr1]SRIF (0.8 x 10(8) M-1min-1).
(6) The rate constant for binding (kon) was 8 x 10(7) M(-1) min(-1).
(7) This slow kon suggests either hindered access to the inhibitory allosteric site or that a fast binding step is followed by a slower conformational change leading to channel inhibition.
(8) The second compound has the same structure as a ganglioside recently found by us (Taki, T., Rokukawa, C., Kasama, T., Kon, K., Ando, S., Abe, T., and Handa, S., J. Biol.
(9) MEP maps of the protonated analogs are correlated to differences in the value of kon, the microscopic association constant.
(10) Kinetic analysis revealed a rapid onset of steady-state inhibition (kon = 1.35 X 10(4) M-1 s-1) followed by slow dissociation of inhibitory complex(es) with a half-life of 8.2 h. The inhibitory complex was shown to consist of E...I...ATP in equilibrium with E...I, Pi, and ADP.
(11) Thor Heyerdahl’s Kon-Tiki expedition was a product of the European enlightenment’s belief in progressive learning.
(12) We need people to have confidence in us.” In a statement to Guardian Australia, Lawrie said: “It’s always open for anyone to put their hand up for leadership, and unlike the CLP our great Labor party has a democratic process.” Kon Vatskalis, a former long-serving Labor member, said on Tuesday he had written to Lawrie asking her to resign “for the good of the party”.
(13) Secretory leukocyte proteinase inhibitor (SLPI) blocks the elastase of all three species with high efficiency; baboon elastase shows the highest association rate constant (kon = 5.6 x 10(7) M-1s-1) followed by human elastase (kon = 4.1 x 10(7) M-1s-1) and finally sheep elastase (kon = 1.2 x 10(7) M-1s-1).
(14) These results enable calculation of real time rate values for the enzyme-primer association (kon = 5.7 x 10(8) M-1 s-1) and dissociation (koff = 1.6 s-1).
(15) Kinetic analysis revealed a kon of 3 x 10(5) M x s-1 at 30 degrees C and pH 5.5.
(16) The reaction of the serine proteinases with the PMN-I was characterized by the determination of the association rate constant kon.
(17) The mutation affects the charge stabilizing system and the primary binding pocket of thrombin as depicted by a decrease in Kon for diisopropylfluorophosphate (9.5-fold) and for N alpha-p-tosyl-L-lysine-chloromethyl ketone (51-fold) and a 39-fold increase in the Ki for benzamidine.
(18) 3H-(-)-bupranolol associated to beta-adrenoceptors of lung membranes with a kon 1.21 X nmol-1 X min-1 and dissociated with a koff of 0.26 min-1.
(19) We now report that the binding rate (kon) of the mAb is 3-fold higher in the presence of Ca2+ than in its absence for both factors IX and IXa; the half-maximal effect was observed at approximately 300 microM Ca2+.
(20) This was verified with a method for estimation of kon values from thrombin generation curves.