(n.) A solid of the form described by the revolution of a right-angled triangle about one of the sides adjacent to the right angle; -- called also a right cone. More generally, any solid having a vertical point and bounded by a surface which is described by a straight line always passing through that vertical point; a solid having a circle for its base and tapering to a point or vertex.
(n.) Anything shaped more or less like a mathematical cone; as, a volcanic cone, a collection of scoriae around the crater of a volcano, usually heaped up in a conical form.
(n.) The fruit or strobile of the Coniferae, as of the pine, fir, cedar, and cypress. It is composed of woody scales, each one of which has one or two seeds at its base.
(n.) A shell of the genus Conus, having a conical form.
(v. t.) To render cone-shaped; to bevel like the circular segment of a cone; as, to cone the tires of car wheels.
Example Sentences:
(1) Implantation of the mouse embryo involves the invasion of the secondary trophoblast giant cells of the ectoplacental cone (EPC) into the uterine decidua.
(2) It is commonly assumed that the visual resolution limit must be equal to or less than the Nyquist frequency of the cone mosaic.
(3) In scanning of more than 20 Hz frequency, the spectral pattern also reflected the characteristics of the cone system.
(4) The function of these triple cones can not be deduced from the behavior patterns of these fishes.
(5) Light-induced cone shortening provides a useful model for stuying nonmuscle contraction because it is linear, slow, and repetitive.
(6) As early as E-28 many growth cones have lamellipodia that extend outward from the core region as far as 10 microns.
(7) RCA-1, which is specific for D-galactose, showed patchy fluorescence on the basal and distal portions of the outer segments of the cones and rods, whereas neuraminidase-treated sections had uniform fluorescence throughout the tissues.
(8) Rats permitted to recover for 13 weeks and then sacrificed had lost almost all their rods (p less than 0.001) while the cones were reduced by about 50% (p less than 0.01).
(9) Rod adaptation had no reliable influence on response to rapid onset in cones or bipolar cells.
(10) Unique domains of the retinal interphotoreceptor matrix (IPM), termed cone matrix sheaths, are composed largely of chondroitin 6-sulfate proteoglycan in most higher mammalian species.
(11) Psychophysical results on human colour matching (Stiles & Burch, 1955; Stiles & Burch, 1959) were well predicted from the spectral sensitivities of the monkey cones.
(12) Our model of voltage dependence of GABA uptake predicts that all colors of light should hyperpolarize H1 cone horizontal cells and other investigators have shown by intracellular recording and dye-marking that type H1 cone horizontal cells hyperpolarize to all wavelengths of light.
(13) During the third stage, the dendritic trees of ganglion cells no longer branch or extend by means of active growth cones.
(14) Growth cones from the neurons contacted the muscle fibers within 6-12 h after isolation.
(15) The results indicate that contact Nd.YAG laser conization for CIN is an excellent conservative therapy from the point of cure rate, safety, indication, operation time and cone specimen, even compared with CO2 laser conization.
(16) In the human retina, which has both cones and rods in abundance, cones, cone bipolars, ganglion cells, horizontal cells, and small and large amacrine cells were labeled.
(17) Neither pH nor composition of liner collection cone had an effect on postthaw acrosomal scores, but the time required for a 50% increase in severely damaged acrosomes was greater for spermatozoa collected in polyethylene than in rubber liner collection cones.
(18) These regenerating nerve fibres together with growth cones make terminals in the form of buttons, rings and loops.
(19) Underneath the envelope, p17 forms the matrix protein layer, while the capsid of the double cone shaped core is built up of p24.
(20) On the model of electrical coupling proposed by Lamb & Simon (1976), this suggests that to the extent that the voltage-dependent desensitization results from an increased conductance and hence an increased shunt of the signals at the plasma membrane, there must be a concomitant increase in the conductance of the electrical pathways linking cones to one another.
Helix
Definition:
(n.) A nonplane curve whose tangents are all equally inclined to a given plane. The common helix is the curve formed by the thread of the ordinary screw. It is distinguished from the spiral, all the convolutions of which are in the plane.
(n.) A caulicule or little volute under the abacus of the Corinthian capital.
(n.) The incurved margin or rim of the external ear. See Illust. of Ear.
(n.) A genus of land snails, including a large number of species.
Example Sentences:
(1) The presence of a few key residues in the amino-terminal alpha-helix of each ligand is sufficient to confer specificity to the interaction.
(2) The elongation of helix III with the addition of helix II at the N-terminus somewhat stabilizes the ordered structure.
(3) The C-terminal sequence contains an amphiphilic alpha-helix of four turns which lies on the surface of the beta-barrel.
(4) The chiral intercalators, at micromolar concentrations, inhibit the reaction of EcoRI, but for each enantiomeric pair it is the lambda enantiomer, which binds only poorly to a B-DNA helix, that inhibits EcoRI preferentially.
(5) The melting profile exhibited two transitions--one at about 35 degrees C and one above 50 degrees C. Our spectral data showed that helices I and II were stable during the first transition, and agreed with other data that helix III was the most likely helix to have melted.
(6) The helix axes, penetrating the hydrophobic region of the bilayers, were oriented neither parallel nor perpendicular to the membrane normal.
(7) The structure of the Z-helix antigen was confirmed by circular dichroism (CD) and U.V.
(8) Conformational predictions based on these sequences confirm their structural homology and indicate the probable existence of two beta-turns, one beta-chain and a long alpha-helix in them.
(9) The nogalose and aminoglucose sugars lie in the minor and major grooves, respectively, of the distorted B-DNA double helix.
(10) The latter, which is external and solvent accessible, is associated with a distortion in the alpha-helix centered around Tyr33 which consists of a significant increase in the CO(i-4)-N(i) and CO(i-4)-NH(i) distances relative to those in the rest of the helix, as well as a significant departure in the phi, psi angles of Tyr33 relative to regular helical geometry.
(11) The AFB1 moiety is face-stacked in the major groove with its long axis approximately perpendicular to the helix axis.
(12) MP8 also was conformed as an alpha-helix, but was amphipatic in the sense that the N-terminal half of the molecule was hydrophilic and the C-terminal half hydrophobic.
(13) A lectin, Helix pomatia agglutinin (HPA), was planted at the surface of rat GEN by the perfusion of the isolated left kidney with neuraminidase (NRD) and HPA.
(14) As a basis for the discussion a possible structure for the DNA complex of the phenylated neutral red is considered in which the extra phenyl ring at N-5 of the phenazinium system, protrudes into the large groove of the DNA helix while the tricyclic part of the ligand is inserted between the DNA base-pairs.
(15) The opsin mutations included reversal of a charged pair conserved in all G protein-coupled receptors at the cytoplasmic border of the third transmembrane helix (mutant CD1), replacement of 13 amino acids in the second cytoplasmic loop (mutant CD2), and deletion of 13 amino acids from the third cytoplasmic loop (mutant EF1).
(16) The remaining 26 independently isolated second-site suppressor mutations all mapped within the amino-terminal DNA binding domain of LexA, at positions 22 (situated in the turn between helix 1 and helix 2) and positions 57, 59, 62, 71 and 73.
(17) In subsequent steps, unassociated Y' directs the synthesis of the complementary oligopurine (R') strand forming a new double helix Y'R' that may direct the synthesis of an oligopyrimidine strand, Y, that is expected to be identical to the first strand that started the whole sequence.
(18) Z-DNA antigen was prepared against poly(dG-dC).poly(dG-dC), which had been converted to the Z-helix conformation in high salt and then stabilized by bromination.
(19) Incubation and heating of the polymers in 1 mM Mn2+ caused the spectral shift reported for the left-handed Z-DNA conformation in the alternating copolymer and the change reported for the triple helix in the homopolymer.
(20) To investigate the ability of a protein to accommodate potentially destabilizing amino acid substitutions, and also to investigate the steric requirements for catalysis, proline was substituted at different sites within the long alpha-helix that connects the amino-terminal and carboxyl-terminal domains of T4 lysozyme.