What's the difference between confine and manacle?

Confine


Definition:

  • (v. t.) To restrain within limits; to restrict; to limit; to bound; to shut up; to inclose; to keep close.
  • (v. i.) To have a common boundary; to border; to lie contiguous; to touch; -- followed by on or with.
  • (n.) Common boundary; border; limit; -- used chiefly in the plural.
  • (n.) Apartment; place of restraint; prison.

Example Sentences:

  • (1) Confined placental chorionic mosaicism is reported in 2% of viable pregnancies cytogenetically analyzed on chorionic villi samplings (CVS) at 9-12 weeks of gestation.
  • (2) Thus, the estrogen-sensitive phase was confined to the early portion of FPH stimulation.
  • (3) Increased amino acid incorporation into hepatic proteins in tumor-bearing animals and also probably in cancer patients is due to a net increased hepatic protein synthesis, probably not confined to acute-phase reactants only.
  • (4) After haemorrhage in conscious rabbits total renal blood flow fell by 25%, this fall being confined to the superficial renal cortex.
  • (5) Pathological changes may, thus, be initially confined to projecting and intrinsic neurons localized in cortical and subcortical olfactory structures; arguments are advanced which favor the view that excitotoxic phenomena could be mainly responsible for the overall degenerative picture.
  • (6) The overall results indicate an inherited impairment of 3-HSD activity confined only to C-21 steroid substrates and, thus, suggest the existence of at least two 3-HSD isoenzymes under independent genetic regulation.
  • (7) In all 4 cases, their reactivity outside the gastrointestinal tract is mainly confined to tracheal epithelium.
  • (8) Similarly at ) degrees glutamine is confined to the simultaneously determined sucrose or mannitol spaces...
  • (9) Although it appears to come within the confines of privacy, assisted suicide constitutes a more radical change in the law than its proponents suggest.
  • (10) Of the strains tested, only the germ-free ND 1 mouse appeared to be susceptible to infection, and this was confined to the stomach mucosa; lesions contained large numbers of hyphal and mycelial forms with blastospores.
  • (11) Confirmatory tests of sinus disease are transillumination (useful in adolescents if interpretation is confined to the extremes--normal or absent); radiographic findings of opacification, mucous membrane thickening, or an air-fluid level; and sinus aspiration (indicated for severe pain, clinical failures, or complicated disease).
  • (12) Significantly more slow acetylators stopped treatment because of nausea or vomiting, or both, but serious toxicity was not confined to either group.
  • (13) He was held there for another eight months in conditions that aroused widespread condemnation , including being held in solitary confinement for 23 hours a day and being made to strip naked at night.
  • (14) At an ultrastructural level, 15-1 immunogold-labeling in the epidermis was confined to the surface of cells exhibiting Birbeck granules.
  • (15) The cytolytic activity of peritoneal SEA reactive effector cells was confined to the TCR alpha beta+ CD4- CD8+ CD45RC- cell population.
  • (16) Three patients were confined to a wheelchair after 3 years of follow-up.
  • (17) This observation confirms that idiotypic recognition is confined to a limited number of clonal products, despite the fact that a very heterogeneous antibody population was used forthe anti-idiotypic immunization.
  • (18) The neighbouring neocortical areas receive afferents neither from the mediodorsal nucleus of the thalamus nor from the ventral mesencephalic tegmentum; their catecholamine innervation is mainly confined to the superficial layers and appears to be of noradrenergic nature.
  • (19) Thus definitive evidence of fetal infection confined to red cell precursors is documented.
  • (20) More patients are being encountered with early Stage I lesions that are confined to the breast or with minimal axillary involvement.

Manacle


Definition:

  • (n.) A handcuff; a shackle for the hand or wrist; -- usually in the plural.
  • (v. t.) To put handcuffs or other fastening upon, for confining the hands; to shackle; to confine; to restrain from the use of the limbs or natural powers.

Example Sentences:

  • (1) • The Film weekly podcast saw host Jason Solomons talk to ... Bruce Robinson (director of Withnail & I) about his new film The Rum Diary ... Errol Morris (director of The Thin Blue Line) about Tabloid - his documentary on Joyce McKinney and the "Manacled Morman" case ... and Guardian film critic Xan Brooks (director of people to decent movies), who helped Jason review Arthur Christmas , The Awakening and Andrea Arnold's Wuthering Heights .
  • (2) Nyingi, who was detained for about nine years , beaten unconscious and bears the marks from leg manacles, whipping and caning, said: "For me … I just wanted the truth to be out.
  • (3) He was beaten unconscious and still bears the marks from leg manacles, whipping and caning.
  • (4) By humanism I mean first of all attempting to dissolve Blake's "mind-forg'd manacles" so as to be able to use one's mind historically and rationally for the purposes of reflective understanding.
  • (5) Too often he has seemed manacled when playing under Wilmots, whose decision to give him the captaincy was far from popular.
  • (6) When the claimants gave evidence at the high court in London last year, Wambugu Wa Nyingi told how he was detained on Christmas Eve 1952 and held for nine years, much of the time in manacles.
  • (7) Confronting it means shaking off the manacles it has imposed on our minds.
  • (8) There are clear analogies with old descriptions of the effects of torture by stretching from manacles or gauntlets or by the rack.
  • (9) One of the high-court claimants, Wambugu Wa Nyingi described how he was detained in 1952 , held for nine years, much of the time in manacles, and beaten unconscious during a particularly notorious massacre at a camp at Hola in which 11 men died.
  • (10) The documents detailed the way suspected insurgents had been beaten to death, burned alive, castrated – like two of the high court claimants – and kept in manacles for years.
  • (11) Robert Holcomb, one of those interviewed in Bloods, Terry's oral history of the war by black veterans, describes how, after being hounded by the FBI, he was "sworn into the army in manacles".