What's the difference between conformation and rotation?

Conformation


Definition:

  • (n.) The act of conforming; the act of producing conformity.
  • (n.) The state of being conformed; agreement; hence; structure, as depending on the arrangement of parts; form; arrangement.

Example Sentences:

  • (1) The interaction of the antibody with both the bacterial and the tissue derived polysialic acids suggests that the conformational epitope critical for the interaction is formed by both classes of compounds.
  • (2) It has been conformed that catalase from bovine liver eliminates only the pro R hydrogen atom from ethanol.
  • (3) The high transition enthalpy for kerasin is ascribed to a lesser accommodation of gauche conformers in the hydrocarbon chains just below the transition temperature.
  • (4) The Tyr side chain had two conformations of comparable energy, one over the ring between the Gln and Asn side chains, and the other with the Tyr side chain away from the ring.
  • (5) In a series of compounds with H2-antihistaminic activity, a conformational analysis was performed based on force field calculations.
  • (6) Recently, we have designed a series of simplified artificial signal sequences and have shown that a proline residue in the signal sequence plays an important role in the secretion of human lysozyme in yeast, presumably by altering the conformation of the signal sequence [Yamamoto, Y., Taniyama, Y., & Kikuchi, M. (1989) Biochemistry 28, 2728-2732].
  • (7) The molecule may already in its native form have an extended conformation containing either free sulfhydryl groups or small S-S loops not affecting mobility in SDS-PAGE.
  • (8) In 0.17 M Na+(aq), tRNA(Phe) exists in its native conformation and the number of strong binding sites (Ka greater than or equal to 10(4)) was estimated to be 3-4 by titration experiments, in agreement with X-ray structural data for crystalline tRNA(Phe) (Jack et al., 1977).
  • (9) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
  • (10) However, it does not and we therefore propose the presence of an unusual DNA conformation in these regions.
  • (11) We propose that, for a GC base pair in B conformation, there are two amino proton exchangeable states--a cytosine amino proton exchangeable state and a guanine amino proton exchangeable state; both require the disruption of only the corresponding interbase H bond.
  • (12) In air-saturated solutions of DNA, yields of 8-hydroxypurines were not influenced greatly by DNA conformation.
  • (13) A detailed stereochemical analysis of known protein structures has been made which shows that: (1) irregular regions of proteins consist of a limited number of standard structures formed by three, four of more residues; (2) an amino acid residue of a protein can adopt one of the six sterically allowed conformations designated here as alpha, alpha L, beta, gamma, delta, and epsilon.
  • (14) The substructural units, 5-14 linear and 5-14 cyclic, have been used as models for MCH-- H-Asp1-Thr-Met-Arg-Cys-Met-Val-Gly-Arg HO-Val17-Glu-Trp-Cys-Pro-Arg-Tyr-Val in 1H-nmr conformational studies.
  • (15) The conformations of each peptide in various solvents were determined by CD and ir spectroscopy in order to relate immunological to structural properties.
  • (16) All data did, however, conform to normal distribution expectations.
  • (17) The conformations of cysteamine, thiazolidine, and thiazolidine-4-carboxylic acid were determined in aqueous solutions using NMR spectroscopy.
  • (18) This structural change opens the heme pocket and modifies the general conformation of the EF segment, thus explaining the increase in oxygen affinity and the achievement of a three-dimensional structure favoring asparagine deamidation.
  • (19) It is likely that the molecule undergoes a conformational change when it is bound to the receptor.
  • (20) The phenylalanine-dependent conformation and the leucine-dependent conformation differ considerably.

Rotation


Definition:

  • (n.) The act of turning, as a wheel or a solid body on its axis, as distinguished from the progressive motion of a revolving round another body or a distant point; thus, the daily turning of the earth on its axis is a rotation; its annual motion round the sun is a revolution.
  • (n.) Any return or succesion in a series.
  • (a.) Pertaining to, or resulting from, rotation; of the nature of, or characterized by, rotation; as, rotational velocity.

Example Sentences:

  • (1) To determine the accuracy of double-contrast arthrography in complete rotator cuff tears, we studied 805 patients thought to have a complete rotator cuff tear who had undergone double-contrast shoulder arthrography (DCSA) between 1978 and 1983.
  • (2) When the posterior capsule was sectioned, no significant changes were noted in the severity of the sag or the rotation.
  • (3) The Ta loop was a smooth, elongated ellipse in configuration and showed clockwise rotation in all planes, as did the P loop.
  • (4) With this system, a brain region loaded with fura-2 was illuminated by a rotating disc bearing three different interference filters of 340, 360 and 380 nm at a rate of 600 rpm.
  • (5) The automatic half of both the motor which advances the trepan as well as the second motor which rotates the trepan is triggered by the sudden change in electrical resistance between the trepan and the patient's internal body fluid, at the final stage of penetration.
  • (6) This series of tests included tests for pathologic nystagmus, saccades, smooth pursuit, and optokinetic nystagmus, as well as bithermal caloric testing and rotational testing.
  • (7) The adherence of 51Cr-labeled platelets to rabbit aortae everted on probes rotated in platelet-red cell suspensions has been measured.
  • (8) We have used a modification of the rotating-frame imaging technique to measure PCr-to-ATP ratio non-invasively in human heart.
  • (9) Experimental evidence suggested that nucleosome rotational positioning is determined by the DNA sequence itself.
  • (10) The X-ray tube rotates outside the detector array at the rate of one revolution per second.
  • (11) The data collection scheme for the scanner uses multiple rotations of a linearly shifted, asymmetric fan beam permitting user-defined variable resolution.
  • (12) The purity and configuration of each isomer of the free acid and N-chloroacetylated derivative were ascertained by: (a) paper chromatography in five solvent systems, (b) elemental analysis, (c) Van Slyke nitrous acid determination of alpha-carbonyl carbon, and (d) Van Slyke ninhydrin determination of alpha-carbonyl carbon, and (e) optical rotation.
  • (13) Based on our experience with the mark I prosthesis we have designed and developed a mark II model which has freedom of axial rotation of the saddle.
  • (14) The reported study demonstrates that performance asymmetries between normal or reflected letters presented in the right and left visual field favors the right visual field when stimulus patterns are blocked and rotated 90 degrees clockwise and favors the left visual field when they are blocked and rotated 90 degrees counterclockwise.
  • (15) Moreover, the majority of the 'out of phase' units showed an increased discharge during side-up animal tilt and side-down neck rotation.
  • (16) 3-D curves were computed with an apparent rotation around the vertical axis Z.
  • (17) Subsequently, due to the rotation of the original polar axis in one hemisphere, the third cleavage plane through one half of the egg is transverse to the third cleavage plane through the other half.
  • (18) This suggests that S1 is a flexible protein with at least two domains that can rotate independently.
  • (19) Per-rotational nystagmus was recorded in rabbits with unilaterally narrowed vertebral arteries or following unilateral cervical sympathectomies.
  • (20) We found that the Gallie system generally allowed significantly more rotation in flexion, extension, axial rotation, and lateral bending than the other three fixation techniques.