(n.) One who conforms; one who complies with established forms or doctrines.
Example Sentences:
(1) The interaction of the antibody with both the bacterial and the tissue derived polysialic acids suggests that the conformational epitope critical for the interaction is formed by both classes of compounds.
(2) It has been conformed that catalase from bovine liver eliminates only the pro R hydrogen atom from ethanol.
(3) The high transition enthalpy for kerasin is ascribed to a lesser accommodation of gauche conformers in the hydrocarbon chains just below the transition temperature.
(4) The Tyr side chain had two conformations of comparable energy, one over the ring between the Gln and Asn side chains, and the other with the Tyr side chain away from the ring.
(5) In a series of compounds with H2-antihistaminic activity, a conformational analysis was performed based on force field calculations.
(6) Recently, we have designed a series of simplified artificial signal sequences and have shown that a proline residue in the signal sequence plays an important role in the secretion of human lysozyme in yeast, presumably by altering the conformation of the signal sequence [Yamamoto, Y., Taniyama, Y., & Kikuchi, M. (1989) Biochemistry 28, 2728-2732].
(7) The molecule may already in its native form have an extended conformation containing either free sulfhydryl groups or small S-S loops not affecting mobility in SDS-PAGE.
(8) In 0.17 M Na+(aq), tRNA(Phe) exists in its native conformation and the number of strong binding sites (Ka greater than or equal to 10(4)) was estimated to be 3-4 by titration experiments, in agreement with X-ray structural data for crystalline tRNA(Phe) (Jack et al., 1977).
(9) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
(10) However, it does not and we therefore propose the presence of an unusual DNA conformation in these regions.
(11) We propose that, for a GC base pair in B conformation, there are two amino proton exchangeable states--a cytosine amino proton exchangeable state and a guanine amino proton exchangeable state; both require the disruption of only the corresponding interbase H bond.
(12) In air-saturated solutions of DNA, yields of 8-hydroxypurines were not influenced greatly by DNA conformation.
(13) A detailed stereochemical analysis of known protein structures has been made which shows that: (1) irregular regions of proteins consist of a limited number of standard structures formed by three, four of more residues; (2) an amino acid residue of a protein can adopt one of the six sterically allowed conformations designated here as alpha, alpha L, beta, gamma, delta, and epsilon.
(14) The substructural units, 5-14 linear and 5-14 cyclic, have been used as models for MCH-- H-Asp1-Thr-Met-Arg-Cys-Met-Val-Gly-Arg HO-Val17-Glu-Trp-Cys-Pro-Arg-Tyr-Val in 1H-nmr conformational studies.
(15) The conformations of each peptide in various solvents were determined by CD and ir spectroscopy in order to relate immunological to structural properties.
(16) All data did, however, conform to normal distribution expectations.
(17) The conformations of cysteamine, thiazolidine, and thiazolidine-4-carboxylic acid were determined in aqueous solutions using NMR spectroscopy.
(18) This structural change opens the heme pocket and modifies the general conformation of the EF segment, thus explaining the increase in oxygen affinity and the achievement of a three-dimensional structure favoring asparagine deamidation.
(19) It is likely that the molecule undergoes a conformational change when it is bound to the receptor.
(20) The phenylalanine-dependent conformation and the leucine-dependent conformation differ considerably.
Minimum
Definition:
(n.) The least quantity assignable, admissible, or possible, in a given case; hence, a thing of small consequence; -- opposed to maximum.
Example Sentences:
(1) Propranolol resulted in a significantly lower mean hourly, mean 24 h and minimum heart rate.
(2) The move would require some secondary legislation; higher fines for employers paying less than the minimum wage would require new primary legislation.
(3) These results suggest that a certain minimum level of expression of c-myc is required for the maintenance of ras transformation in NIH 3T3 cells.
(4) Due to continued disease relapse in this group (four of eight patients), long-term survivors should not be identified for a minimum of 3.5 years from the time of initial therapy.
(5) At concentrations several hundredfold higher than the equivalents present in the minimum concentration of rat skin soluble collagen required for platelet aggregation, neither Hyl-Gal (at 29 muM) nor Hyl-Gal-Glc (at 18 muM) caused platelet aggregation or inhibited platelet aggregation by native collagen.
(6) The morbidity is well known and if properly anticipated can be reduced to a minimum by judicious use of antibacterial agents and early surgical intervention when appropriate.
(7) Analysis was performed on all patients who received any amount of therapy (VSG) and on the Adequately Treated Group (ATG), who had received 5000 or more rads radiotherapy, two or more courses of chemotherapy, and had a minimum survival of 8 or more weeks (the interval that would have been required to have received either the radiotherapy or chemotherapy).
(8) However, the effect of prior jaw motion and the effect of the recording site on the EMG amplitudes and on the vertical dimension of minimum EMG activity have not been documented.
(9) Leaders of Tory local government are preparing radical proposals for minimum 10% cuts in public spending in the search for savings.
(10) It was shown that the levels of ATP and ADP in the mycelium depended on the carbon source: the maximum and minimum ATP concentrations were found on the glucose and acetate media respectively, the maximum and minimum ADP concentrations showed inverse dependence.
(11) On the tangential views the inclinations of the future implants were estimated and the part of the alveolar ridge having a width less than 5 mm, which is the minimum width for housing an implant, was compiled.
(12) The activity was maximum at the 16-32-cell stage and then decreased to a minimum at the mesenchyme blastula stage.
(13) Minimum investment is £200, and the share prospectus states that interest of 6% will be paid from year three of trading.
(14) The 30-fold chromosomally mediated and 15-fold R-plasmid NT resistance were 3- and 5-fold respectively reduced by a minimum inhibitory combination of Tp + NT.
(15) Minimum inhibitory concentrations for these four antibiotics have been determined against 393 bacterial strains (13 species from eight genera) isolated from clinical materialKanamycin was the least active, 89% of the Pseudomonas aeruginosa strains being resistant.
(16) The number of seats has been reduced from 72,000 to 68,000, with another 12,000 to be added after the Games to meet the 80,000 minimum required in case Japan launches a bid to host the football World Cup.
(17) A minimum of 4 sheeps' heads, obtained weekly over 24 months from the Pretoria Municipal Abattoir, was examined for infestation.
(18) Variations in bioavailability and intestinal absorption are important factors in the determination of dosage and should be reduced to a minimum by improved pharmaceutical formulations.
(19) With a minimum review period of 6 months complete remission of synovitis was obtained in 20%, while 63% gained symptomatic relief, with some reduction of synovitis.
(20) The minimum contraction produced by the threshold current involved usually three or four, sometimes two, sarcomers on both sides of the injecting pipette but contraction involving only one sarcomere was not observered.