(a.) Worthy of consideration, borne in mind, or attended to.
(a.) Of some distinction; noteworthy; influential; respectable; -- said of persons.
(a.) Of importance or value.
Example Sentences:
(1) However, as other patients who lived at the periphery of the Valserine valley do not appear to be related to any patients living in the valley, and because there has been considerable immigration into the valley, a number of hypotheses to explain the distribution of the disease in the region remain possible.
(2) Theoretical findings on sterilization and disinfection measures are useless for the dental practice if their efficiency is put into question due to insufficient consideration of the special conditions of dental treatment.
(3) Angiopathic and traumatic influences conditioned by metabolism, apart from local peculiarities are taken into consideration.
(4) Overall length of stay found in this study (14.02 days) is considerably higher than Indian optimum.
(5) In addition to the phase diagrams reported here for these two binary mixtures, a brief theoretical discussion is given of other possible phase diagrams that may be appropriate to other lipid mixtures with particular consideration given to the problem of crystalline phases of different structures and the possible occurrence of second-order phase transitions in these mixtures.
(6) And that, as much as the “on water, operational” considerations, is why we are being kept in the dark.
(7) Valvular stenoses of the bronchi and especially of the bronchioles in various types of primary pulmonary disease are of considerable importance etiologically.
(8) E-RFC enriched for T lymphocytes and depleted of macrophages synthesized considerable DNA in response to stimulation with PHA, but were unable to produce significant bone resorbing activity in tissue culture unless macrophages were re-added to the E-RFC.
(9) Full consideration should be given to the dynamics of motion when assessing risk factors in working tasks.
(10) These results indicate that the hormonal status should be taken into consideration in studies dealing with platelet MAO activity in depressed women.
(11) Considerate touches includes the free use of cruiser bicycles (the best method of tackling the Palm Springs main drag), home-baked cookies … and if you'd like to get married, ask the manager: he's a minister.
(12) United believe it is more likely the right-back can be bought in the summer but are exploring what would represent the considerable coup of acquiring the 26-year-old immediately.
(13) There is a considerably larger variability of the mercury levels in urine than in blood.
(14) The current of research on the alleged activity of such "inhibitors" is taken into consideration.
(15) A considerably greater increase in the peak plasma OT concentration resulted when hungry foster litters of 6 pups were suckled after the mothers' own 6 pups had been suckled.
(16) B and C, were identified and their relative proportions shown to be considerably greater in the foetus than in the adult.
(17) Precipitin tests had considerable advantages over other methods of serological diagnosis of influenza.
(18) Strains 1120-A-83-013 and B205BT produced considerably higher levels of dermonecrotic toxin activity than did strains CSU-P-1 and 64-C-0406.
(19) These levels are sufficient to maintain normal in vivo rates of mRNA and rRNA synthesis, but the average density of packing of polymerases on DNA is considerably less than the maximum density predicted by Miller and Bakken (1972), suggesting that initiation of polymerases of DNA is a limiting factor in the control of transcription.
(20) The antibody-hapten profiles revealed that the DNCB-fed animalss contained predominatly IgG2 in their serum by the time of their initial bleedings, whereas sensitized animals still contained a considerable proportion of more acidic antibodies having marked charge heterogeneity.
Substantial
Definition:
(a.) Belonging to substance; actually existing; real; as, substantial life.
(a.) Not seeming or imaginary; not illusive; real; solid; true; veritable.
(a.) Corporeal; material; firm.
(a.) Having good substance; strong; stout; solid; firm; as, substantial cloth; a substantial fence or wall.
(a.) Possessed of goods or an estate; moderately wealthy; responsible; as, a substantial freeholder.
Example Sentences:
(1) The predicted non-Lorentzian line shapes and widths were found to be in good agreement with experimental results, indicating that the local orientational order (called "packing" by many workers) in the bilayers of small vesicles and in multilamellar membranes is substantially the same.
(2) 10D1 mAb induced a substantial proliferation of peripheral blood T cells when cross-linked with goat anti-mouse Ig antibody.
(3) Estimates of potential for gastrointestinal side effects using the rat enteropooling assay and in vivo monkey effects indicate that diarrhea will be substantially reduced with retention of uterine stimulating potency.
(4) Previous studies in this laboratory with particulate Mn3O4 have shown that preweanling rats have substantially higher tissue Mn concentrations than similarly treated adults, indicating possible differences in uptake or elimination or both.
(5) A more substantial decrease was found in Aberdeen and the larger towns near to Aberdeen than in the smaller towns further from the city.
(6) In contrast, human breast milk contained substantially increased levels of immunoreactive PTHrP.
(7) It was found that there was a substantial increase in mortality rates in the area under the jets where there was large noise radiation.
(8) But the amount of time spent above SPA has differed substantially between men and women due to women both living longer, and reaching state pension age earlier.
(9) Although statistical analysis did not show dramatic changes in all these parameters, some individual extreme values were substantially altered.
(10) Cholestyramine resin was beneficial in reducing stool bulk but had no substantial effect on fat absorption.
(11) Accordingly, LPA proved an extremely stable characteristic which did not show any substantial variations in the course of five years.
(12) This hypothesis is difficult to substantiate with direct measurements using human subjects.
(13) Mitogen-stimulated cells always contain substantially higher levels of LDL receptor messenger RNA than corresponding resting cells.
(14) Considerable glucose 6-phosphatase activity survived 240min of treatment with phospholipase C at 5 degrees C, but in the absence of substrate or at physiological glucose 6-phosphate concentrations the delipidated enzyme was completely inactivated within 10min at 37 degrees C. However, 80mM-glucose 6-phosphate stabilized it and phospholipid dispersions substantially restored thermal stability.
(15) Amine metabolites, 5-hydroxyindoleacetic acid (5HIAA), and homovanillic acid (HVA) were not substantially affected by sleep deprivation, although there was a significant interaction of clinical response and direction of 3-methoxy-4-hydroxyphenylglycol (MHPG) change.
(16) The department of dietetics at a large teaching hospital has substantially reduced its food and labor costs through use of computerized systems that ensure efficient inventory management, recipe standardization, ingredient control, quantity and quality control, and identification of productive man-hours and appropriate staffing levels.
(17) Substantial percentages of both physicians and medical students reported access to drugs, family histories of substance abuse, stress at work and home, emotional problems, and sensation seeking.
(18) For further education, this would be my priority: a substantial increase in funding and an end to tinkering with the form of qualifications and bland repetition of the “parity of esteem” trope.
(19) The family members of depressed patients with six or more groups of DSM-III symptoms of major depression exhibited substantially higher rates of mood disorders than the family members of depressed patients with fewer than six groups of symptoms and the family members of patients with nonaffective disorders.
(20) The results presented here substantiate the hypothesis that in S. cerevisiae trehalose supplies energy during dormancy of the spores and not during the germination process.