(v. t.) Firm; solid; fixed; immovable; -- opposed to fluid.
(v. t.) Not liable, or given, to change; permanent; regular; continuous; continually recurring; steadfast; faithful; not fickle.
(v. t.) Remaining unchanged or invariable, as a quantity, force, law, etc.
(v. t.) Consistent; logical.
(n.) That which is not subject to change; that which is invariable.
(n.) A quantity that does not change its value; -- used in countradistinction to variable.
Example Sentences:
(1) Between 25 and 40 degrees C, the thermal dependencies of VR and f were approximately constant (Q10's of 1.31 and 1.36 got VR and f, respectively).
(2) By 24 hr, rough endoplasmic reticulum in thecal cells increased from 4.2 to 7% of cell volume, while the amount in granulosa cells increased from less than 3.5% to more than 10%; the quantity remained relatively constant in the theca but declined to prestimulation values in the granulosa layer.
(3) The norepinephrine values remained constant on the three days.
(4) At the same time the duodenum can be isolated from the stomach and maintained under constant stimulus by a continual infusion at regulated pressure, volume and temperature into the distal cannula.
(5) Rise time and fall time constants have been quantified for describing kinetics of response.
(6) Standard nerve conduction techniques using constant measured distances were applied to evaluate the median, ulnar and radial nerves.
(7) The stopped-flow technique was used to measure the rate constants for the reactions between the oxidized forms of peroxidase with luminol and the following substrates: p-iodophenol, p-bromophenol, p-clorophenol, o-iodophenol, m-iodophenol, luciferin, and 2-iodo-6-hydroxybenzothiazole.
(8) The family comprises at least three variable (V) gene segments, three constant (C) gene segments, and three junction (J) gene segments.
(9) This value is about 30 times higher than the association constant for guanine-cytosine base pair formation under the same experimental conditions.
(10) There is a relationship between the duration of stimulation (t) and the total heat production (H) of the type H = A plus bt, where A and b are constants.
(11) Naloxone injection into those rats exposed to constant illumination significantly increased hypothalamic levels of beta-endorphin compared to saline injected controls.
(12) [5alpha-(3)H]5alpha-Androst-16-en-3-one (5alpha-androstenone) was infused at a constant rate for 180min into the spermatic artery of a sexually mature boar.
(13) The birds were maintained at a constant temperature in, dim green light.
(14) We previously established that the binding constant (Ka) of this receptor site for the chemically synthesized model AGE, 2-(2-furoyl)-4(5)-(2-furanyl)-1H- imidazole-butyric acid (FFI-BA), on cells of the mouse macrophagelike cell line RAW 264.7 is identical to that for AGE proteins.
(15) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(16) The matter is now in the hands of the Guernsey police and the law officers.” One resident who is a constant target of the paper and has complained to police, Rosie Guille, said the allegations had a “huge impact on morale” on the island.
(17) Stability of kinetic constants for a long period of time is demonstrated.
(18) The association constants K'A, KN, and K'N in the scheme (see article), were determined for the magnesium salts of ADP, adenyl-5'-yl imidodiphosphate AMP-P(NH)P, and PPi.
(19) As total pancreatectomy markedly reduces the pancreatic hormone level, leading to a mortal hypoglycaemia, we attempted to maintain plasma glucose within the normal range by constant I.V.
(20) Utilizing a range of operative Michaelis-Menten parameters that characterize phenytoin elimination via a single capacity-limited pathway, a situation assuming instantaneous absorption (case I) is compared with the situation in which continuous constant-rate absorption occurs (case II).
Helix
Definition:
(n.) A nonplane curve whose tangents are all equally inclined to a given plane. The common helix is the curve formed by the thread of the ordinary screw. It is distinguished from the spiral, all the convolutions of which are in the plane.
(n.) A caulicule or little volute under the abacus of the Corinthian capital.
(n.) The incurved margin or rim of the external ear. See Illust. of Ear.
(n.) A genus of land snails, including a large number of species.
Example Sentences:
(1) The presence of a few key residues in the amino-terminal alpha-helix of each ligand is sufficient to confer specificity to the interaction.
(2) The elongation of helix III with the addition of helix II at the N-terminus somewhat stabilizes the ordered structure.
(3) The C-terminal sequence contains an amphiphilic alpha-helix of four turns which lies on the surface of the beta-barrel.
(4) The chiral intercalators, at micromolar concentrations, inhibit the reaction of EcoRI, but for each enantiomeric pair it is the lambda enantiomer, which binds only poorly to a B-DNA helix, that inhibits EcoRI preferentially.
(5) The melting profile exhibited two transitions--one at about 35 degrees C and one above 50 degrees C. Our spectral data showed that helices I and II were stable during the first transition, and agreed with other data that helix III was the most likely helix to have melted.
(6) The helix axes, penetrating the hydrophobic region of the bilayers, were oriented neither parallel nor perpendicular to the membrane normal.
(7) The structure of the Z-helix antigen was confirmed by circular dichroism (CD) and U.V.
(8) Conformational predictions based on these sequences confirm their structural homology and indicate the probable existence of two beta-turns, one beta-chain and a long alpha-helix in them.
(9) The nogalose and aminoglucose sugars lie in the minor and major grooves, respectively, of the distorted B-DNA double helix.
(10) The latter, which is external and solvent accessible, is associated with a distortion in the alpha-helix centered around Tyr33 which consists of a significant increase in the CO(i-4)-N(i) and CO(i-4)-NH(i) distances relative to those in the rest of the helix, as well as a significant departure in the phi, psi angles of Tyr33 relative to regular helical geometry.
(11) The AFB1 moiety is face-stacked in the major groove with its long axis approximately perpendicular to the helix axis.
(12) MP8 also was conformed as an alpha-helix, but was amphipatic in the sense that the N-terminal half of the molecule was hydrophilic and the C-terminal half hydrophobic.
(13) A lectin, Helix pomatia agglutinin (HPA), was planted at the surface of rat GEN by the perfusion of the isolated left kidney with neuraminidase (NRD) and HPA.
(14) As a basis for the discussion a possible structure for the DNA complex of the phenylated neutral red is considered in which the extra phenyl ring at N-5 of the phenazinium system, protrudes into the large groove of the DNA helix while the tricyclic part of the ligand is inserted between the DNA base-pairs.
(15) The opsin mutations included reversal of a charged pair conserved in all G protein-coupled receptors at the cytoplasmic border of the third transmembrane helix (mutant CD1), replacement of 13 amino acids in the second cytoplasmic loop (mutant CD2), and deletion of 13 amino acids from the third cytoplasmic loop (mutant EF1).
(16) The remaining 26 independently isolated second-site suppressor mutations all mapped within the amino-terminal DNA binding domain of LexA, at positions 22 (situated in the turn between helix 1 and helix 2) and positions 57, 59, 62, 71 and 73.
(17) In subsequent steps, unassociated Y' directs the synthesis of the complementary oligopurine (R') strand forming a new double helix Y'R' that may direct the synthesis of an oligopyrimidine strand, Y, that is expected to be identical to the first strand that started the whole sequence.
(18) Z-DNA antigen was prepared against poly(dG-dC).poly(dG-dC), which had been converted to the Z-helix conformation in high salt and then stabilized by bromination.
(19) Incubation and heating of the polymers in 1 mM Mn2+ caused the spectral shift reported for the left-handed Z-DNA conformation in the alternating copolymer and the change reported for the triple helix in the homopolymer.
(20) To investigate the ability of a protein to accommodate potentially destabilizing amino acid substitutions, and also to investigate the steric requirements for catalysis, proline was substituted at different sites within the long alpha-helix that connects the amino-terminal and carboxyl-terminal domains of T4 lysozyme.