(v. t.) To secure by bonds; to chain; to bond or confine; to hold tightly; to constringe.
(v. t.) To bring into a narrow compass; to compress.
(v. t.) To hold back by force; to restrain; to repress.
(v. t.) To compel; to force; to necessitate; to oblige.
(v. t.) To violate; to ravish.
(v. t.) To produce in such a manner as to give an unnatural effect; as, a constrained voice.
Example Sentences:
(1) Paul Johnson, the IFS director, said: “Osborne’s new fiscal charter is much more constraining than his previous fiscal rules.
(2) The parameters of the multiplet signal are consistent with the presence of a sterically constrained tyrosine phenoxyl radical.
(3) The variations in behavior and physiology across the year were considered in terms of factors constraining the timing of the natural reproductive pattern.
(4) First, chains are constrained by their inability to penetrate the boundary.
(5) The prepro form of ET-1 was inactive, suggesting that mature ET peptides are constrained in an inactive conformation within the preproET species.
(6) A method is presented for testing the equality of some or all (constrained or unconstrained) optima in a response surface analysis.
(7) The genius of a democracy governed by the rule of law, our democracy, is that it both empowers the majority through the ballot box, and constrains the majority, its government, so that it is bound by law.” Turnbull added: “Why does Daesh [another term for Islamic State] hate us?
(8) Often, a single, constrained peptide analogue can be designed, which will have many of the desired biological and biophysical properties, and will serve as a template.
(9) Because the rigor of the present day "scientific method" demands clearcut and reproducible results and investigations require predictable performance of the parasite in an evenly maintained host that is in a highly constrained environment, we should not wonder why we cannot produce the events of nature.
(10) In the first stage, the constrained random ordering of the stimuli is generated as specified by the user.
(11) Intrauterine influences which retard fetal weight gain may irrecoverably constrain the growth of the airways.
(12) "We have rhetorical pressure, which we are using, and we have the Seventh Fleet, which nobody wants to use, and in between our options are more constrained," he said.
(13) If correctional institutions constrain inmates' access to social benefits, means exist to protect incarcerated people's rights in health studies.
(14) Her ability to estimate time intervals and general time perspective was constrained by her impoverished store of knowledge for personal experiences.
(15) The immobilization successfully constrained the anteroinferior displacement of the maxilla and zygomatic bone on the fused side.
(16) In a previous study of push-off without plantar flexion it was shown that the transformation of knee angular velocity into translation of the body is constrained by the fact that velocity difference between hip and ankle has to reach its peak value a long time before the knee is extended.
(17) As there is no evidence for a close evolutionary link between kinesin and myosin, these and other similarities may represent convergence to set of common functional properties which are constrained by the requirements of protein structure and the use of ATP hydrolysis as a source of energy.
(18) By lengthening the ventricular effective refractory period, trains of conditioning stimuli could prevent or terminate tachycardias, but this possibility is constrained, at present, by the spatial limitations of the technique.
(19) The data suggest that the biological effects of RA may be constrained or augmented by differential regulation of its own receptor gene expression.
(20) A biological process serves as a source and its products are subject t] local dispersive fluid forces constrained by chaotic streamlines.
Constraint
Definition:
(n.) The act of constraining, or the state of being constrained; that which compels to, or restrains from, action; compulsion; restraint; necessity.
Example Sentences:
(1) Poor lipophilicity and extremely low plasma concentrations impose severe constraints.
(2) Specifically, we apply techniques of data preprocessing, orthogonality constraints, and validation of solutions in a complete TC analysis, for the first time using actual MEP data.
(3) When this constraint was released by various treatments altering membrane structure UDP-glucose markedly inhibited bilirubin glucuronidation.
(4) For each theory, a constraint on preformance is proposed based on interference between the "analytic" and "synthetic" pitch perception modes.
(5) spectroscopy for the collection of conformational constraints, calculation of the protein structure from the n.m.r.
(6) Subjects initially chose to work for the higher rated food, but as the constraints for this food increased, subjects chose to work for the lower rated food.
(7) Dictated by underlying physicochemical constraints, deceived at times by the lulling tones of the siren entropy, and constantly vulnerable to the vagaries of other more pervasive forms of biological networking and information transfer encoded in the genes of virus and invading microorganisms, protein biorecognition in higher life forms, and particularly in mammals, represents the finely tuned molecular avenues for the genome to transfer its information to the next generation.
(8) Continuing pressure on household finances during the next 12 months will no doubt remain a constraint."
(9) Lateralization may be an expression of reflex constraints bound initially to the infant's tonic-neck posture, with later development less reflex-patterned during the acquisition of more sophisticated information-processing strategies.
(10) His anti-politics act may just be a shtick – pretending he's still on Have I Got News for You, satirising politics even though he's right at the centre of it – but it liberates him from the usual constraints.
(11) Given that lattice constraints strongly inhibit large-scale conformational changes these results allow us to identify the average solution structure with the 'open' conformer determined crystallographically.
(12) A dynamic optimization technique to minimize jerk cost under the constraint on jerk input was applied to interpret the results, assuming that a major goal of skilled movements was to produce optimally smooth movements.
(13) Its main advantages, when compared to previously available programs using the variable target function algorithm, are a significant reduction of the computation time, and a novel treatment of experimental distance constraints involving diastereotopic groups of hydrogen atoms that were not individually assigned.
(14) For one, the ability to raise a larger deposit is acting as a constraint.
(15) When the constraints are high, a Michaelis-Menten equation can be used to model the kinetics for interfacial concentrations lower than the concentration leading to the maximum reaction rate.
(16) Estimators of the model parameters are defined under general exact and stochastic linear constraints.
(17) A careful reorganization of priorities would thus be helpful in improving neonatal care in Jamaica, even in the presence of financial constraints.
(18) Emergence and spread of antibiotic-resistant bacteria is augmented in settings in which treatment may be inadequate because of socioeconomic constraints and where there is crowding and poor sanitation.
(19) The estrogen receptor seems to have a moderate tolerance for bulky substituents: All of the halogen and halomethyl substituents bind with an affinity at least 50% that of estradiol; in the three atom alkyl series, the affinity declined markedly from propargyl (44%) and allyl (38%) to propyl (5%), suggestive of detailed steric constraints or a preference for unsaturation.
(20) Bias is controlled by the use of least-squares curve fitting for all assays, and constraints on the elimination of outlier points.