(v. t.) To secure by bonds; to chain; to bond or confine; to hold tightly; to constringe.
(v. t.) To bring into a narrow compass; to compress.
(v. t.) To hold back by force; to restrain; to repress.
(v. t.) To compel; to force; to necessitate; to oblige.
(v. t.) To violate; to ravish.
(v. t.) To produce in such a manner as to give an unnatural effect; as, a constrained voice.
Example Sentences:
(1) Paul Johnson, the IFS director, said: “Osborne’s new fiscal charter is much more constraining than his previous fiscal rules.
(2) The parameters of the multiplet signal are consistent with the presence of a sterically constrained tyrosine phenoxyl radical.
(3) The variations in behavior and physiology across the year were considered in terms of factors constraining the timing of the natural reproductive pattern.
(4) First, chains are constrained by their inability to penetrate the boundary.
(5) The prepro form of ET-1 was inactive, suggesting that mature ET peptides are constrained in an inactive conformation within the preproET species.
(6) A method is presented for testing the equality of some or all (constrained or unconstrained) optima in a response surface analysis.
(7) The genius of a democracy governed by the rule of law, our democracy, is that it both empowers the majority through the ballot box, and constrains the majority, its government, so that it is bound by law.” Turnbull added: “Why does Daesh [another term for Islamic State] hate us?
(8) Often, a single, constrained peptide analogue can be designed, which will have many of the desired biological and biophysical properties, and will serve as a template.
(9) Because the rigor of the present day "scientific method" demands clearcut and reproducible results and investigations require predictable performance of the parasite in an evenly maintained host that is in a highly constrained environment, we should not wonder why we cannot produce the events of nature.
(10) In the first stage, the constrained random ordering of the stimuli is generated as specified by the user.
(11) Intrauterine influences which retard fetal weight gain may irrecoverably constrain the growth of the airways.
(12) "We have rhetorical pressure, which we are using, and we have the Seventh Fleet, which nobody wants to use, and in between our options are more constrained," he said.
(13) If correctional institutions constrain inmates' access to social benefits, means exist to protect incarcerated people's rights in health studies.
(14) Her ability to estimate time intervals and general time perspective was constrained by her impoverished store of knowledge for personal experiences.
(15) The immobilization successfully constrained the anteroinferior displacement of the maxilla and zygomatic bone on the fused side.
(16) In a previous study of push-off without plantar flexion it was shown that the transformation of knee angular velocity into translation of the body is constrained by the fact that velocity difference between hip and ankle has to reach its peak value a long time before the knee is extended.
(17) As there is no evidence for a close evolutionary link between kinesin and myosin, these and other similarities may represent convergence to set of common functional properties which are constrained by the requirements of protein structure and the use of ATP hydrolysis as a source of energy.
(18) By lengthening the ventricular effective refractory period, trains of conditioning stimuli could prevent or terminate tachycardias, but this possibility is constrained, at present, by the spatial limitations of the technique.
(19) The data suggest that the biological effects of RA may be constrained or augmented by differential regulation of its own receptor gene expression.
(20) A biological process serves as a source and its products are subject t] local dispersive fluid forces constrained by chaotic streamlines.
Demonstration
Definition:
(n.) The act of demonstrating; an exhibition; proof; especially, proof beyond the possibility of doubt; indubitable evidence, to the senses or reason.
(n.) An expression, as of the feelings, by outward signs; a manifestation; a show.
(n.) The exhibition and explanation of a dissection or other anatomical preparation.
(n.) (Mil.) a decisive exhibition of force, or a movement indicating an attack.
(n.) The act of proving by the syllogistic process, or the proof itself.
(n.) A course of reasoning showing that a certain result is a necessary consequence of assumed premises; -- these premises being definitions, axioms, and previously established propositions.
Example Sentences:
(1) The Na+ ionophore, gramicidin, had a small but significant inhibitory effect on Na(+)-dependent KG uptake, demonstrating that KG uptake was not the result of an intravesicular positive Na+ diffusion potential.
(2) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(3) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(4) Of the patients 73% demonstrated clinically normal sensibility test results within 23 days after operation.
(5) Lucy and Ed will combine coverage of hard and breaking news with a commitment to investigative journalism, which their track record so clearly demonstrates”.
(6) These immunocytochemical studies clearly demonstrated that cells encountered within the fibrous intimal thickening in the vein graft were inevitably smooth muscle cell in origin.
(7) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(8) Using monoclonal antibodies directed against the plasma membrane of Madin-Darby canine kidney (MDCK) cells, we demonstrated previously that a glycoprotein with an Mr = 23,000 (gp23) had a non-polarized cell surface distribution and was observed on both the apical and basolateral membranes (Ojakian, G. K., Romain, R. E., and Herz, R. E. (1987) Am.
(9) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
(10) Intravesical BCG is clearly superior to oral BCG, and controlled studies have demonstrated that percutaneous administration is not necessary.
(11) We have previously shown that serotonin is present in secretory granules of frog adrenochromaffin cells; concurrently, we have demonstrated that serotonin is a potent stimulator of corticosterone and aldosterone secretion by adrenocortical cells.
(12) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
(13) The results demonstrated that K2PtCl4 was bound to a greater degree than CDDP in this system with 3-5 and 1-2 platinum atoms respectively, bound per transferrin molecule.
(14) These studies, in addition to demonstrating that the placenta contains TRH deamidase activity, suggest that losses of fetal TRH through the placenta are not large.
(15) Light microscopic studies of pancreata from mice sacrificed at this time demonstrated insulitis and beta cell necrosis.
(16) Western blot analysis of these mitochondria using an antibody against carnitine palmitoyltransferase II purified from beef heart demonstrates a 68-kDa protein, which under ischemic conditions apparently is decreased by 2 kDa.
(17) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(18) In 1 of the 3, anterior capsular detachment was also demonstrated radiographically and confirmed surgically.
(19) This result demonstrates that branching enzyme belongs to a family of the amylolytic enzymes.
(20) Histological studies of nerves 2 years following irradiation demonstrated loss of axons and myelin, with a corresponding increase in endoneurial, perineurial, and epineurial connective tissue.