(v. t.) To secure by bonds; to chain; to bond or confine; to hold tightly; to constringe.
(v. t.) To bring into a narrow compass; to compress.
(v. t.) To hold back by force; to restrain; to repress.
(v. t.) To compel; to force; to necessitate; to oblige.
(v. t.) To violate; to ravish.
(v. t.) To produce in such a manner as to give an unnatural effect; as, a constrained voice.
Example Sentences:
(1) Paul Johnson, the IFS director, said: “Osborne’s new fiscal charter is much more constraining than his previous fiscal rules.
(2) The parameters of the multiplet signal are consistent with the presence of a sterically constrained tyrosine phenoxyl radical.
(3) The variations in behavior and physiology across the year were considered in terms of factors constraining the timing of the natural reproductive pattern.
(4) First, chains are constrained by their inability to penetrate the boundary.
(5) The prepro form of ET-1 was inactive, suggesting that mature ET peptides are constrained in an inactive conformation within the preproET species.
(6) A method is presented for testing the equality of some or all (constrained or unconstrained) optima in a response surface analysis.
(7) The genius of a democracy governed by the rule of law, our democracy, is that it both empowers the majority through the ballot box, and constrains the majority, its government, so that it is bound by law.” Turnbull added: “Why does Daesh [another term for Islamic State] hate us?
(8) Often, a single, constrained peptide analogue can be designed, which will have many of the desired biological and biophysical properties, and will serve as a template.
(9) Because the rigor of the present day "scientific method" demands clearcut and reproducible results and investigations require predictable performance of the parasite in an evenly maintained host that is in a highly constrained environment, we should not wonder why we cannot produce the events of nature.
(10) In the first stage, the constrained random ordering of the stimuli is generated as specified by the user.
(11) Intrauterine influences which retard fetal weight gain may irrecoverably constrain the growth of the airways.
(12) "We have rhetorical pressure, which we are using, and we have the Seventh Fleet, which nobody wants to use, and in between our options are more constrained," he said.
(13) If correctional institutions constrain inmates' access to social benefits, means exist to protect incarcerated people's rights in health studies.
(14) Her ability to estimate time intervals and general time perspective was constrained by her impoverished store of knowledge for personal experiences.
(15) The immobilization successfully constrained the anteroinferior displacement of the maxilla and zygomatic bone on the fused side.
(16) In a previous study of push-off without plantar flexion it was shown that the transformation of knee angular velocity into translation of the body is constrained by the fact that velocity difference between hip and ankle has to reach its peak value a long time before the knee is extended.
(17) As there is no evidence for a close evolutionary link between kinesin and myosin, these and other similarities may represent convergence to set of common functional properties which are constrained by the requirements of protein structure and the use of ATP hydrolysis as a source of energy.
(18) By lengthening the ventricular effective refractory period, trains of conditioning stimuli could prevent or terminate tachycardias, but this possibility is constrained, at present, by the spatial limitations of the technique.
(19) The data suggest that the biological effects of RA may be constrained or augmented by differential regulation of its own receptor gene expression.
(20) A biological process serves as a source and its products are subject t] local dispersive fluid forces constrained by chaotic streamlines.
Direct
Definition:
(a.) Straight; not crooked, oblique, or circuitous; leading by the short or shortest way to a point or end; as, a direct line; direct means.
(a.) Straightforward; not of crooked ways, or swerving from truth and openness; sincere; outspoken.
(a.) Immediate; express; plain; unambiguous.
(a.) In the line of descent; not collateral; as, a descendant in the direct line.
(a.) In the direction of the general planetary motion, or from west to east; in the order of the signs; not retrograde; -- said of the motion of a celestial body.
(v. t.) To arrange in a direct or straight line, as against a mark, or towards a goal; to point; to aim; as, to direct an arrow or a piece of ordnance.
(v. t.) To point out or show to (any one), as the direct or right course or way; to guide, as by pointing out the way; as, he directed me to the left-hand road.
(v. t.) To determine the direction or course of; to cause to go on in a particular manner; to order in the way to a certain end; to regulate; to govern; as, to direct the affairs of a nation or the movements of an army.
(v. t.) To point out to with authority; to instruct as a superior; to order; as, he directed them to go.
(v. t.) To put a direction or address upon; to mark with the name and residence of the person to whom anything is sent; to superscribe; as, to direct a letter.
(v. i.) To give direction; to point out a course; to act as guide.
(n.) A character, thus [/], placed at the end of a staff on the line or space of the first note of the next staff, to apprise the performer of its situation.
Example Sentences:
(1) Direct fetal digitalization led to a reduction in umbilical artery resistance, a decline in the abdominal circumference from 20.3 to 17.8 cm, and resolution of the ascites within 72 h. Despite this dramatic response to therapy, fetal death occurred on day 5 of treatment.
(2) One hundred and twenty-seven states have said with common voice that their security is directly threatened by the 15,000 nuclear weapons that exist in the arsenals of nine countries, and they are demanding that these weapons be prohibited and abolished.
(3) However, when first trimester specimens were analyzed, the direct-product measurements were significantly larger than the corresponding 3H2O assay results.
(4) The generally accepted hypothesis is a coronary spasm but a direct cardiotoxicity of 5-FU cannot be.
(5) One hour after direct mechanical cardiomassage (DMCM) a moderately pronounced edema of the intercellular spaces in the basal compartment of the seminiferous epithelium, normal content of lactate and succinate dehydrogenases, and a certain decrease in the activity of glucose-6-phosphate dehydrogenases and NAD- and NADP-diaphorases were noted.
(6) Using monoclonal antibodies directed against the plasma membrane of Madin-Darby canine kidney (MDCK) cells, we demonstrated previously that a glycoprotein with an Mr = 23,000 (gp23) had a non-polarized cell surface distribution and was observed on both the apical and basolateral membranes (Ojakian, G. K., Romain, R. E., and Herz, R. E. (1987) Am.
(7) Results indicated a .85 probability that Directive Guidance would be followed by Cooperation; a .67 probability that Permissiveness would lead to Noncooperation; and a .97 likelihood that Coerciveness would lead to either Noncooperation or Resistance.
(8) Multiple overlapping thin 3D slab acquisition is presented as a magnitude contrast (time of flight) technique which combines advantages from multiple thin slice 2D and direct 3D volume acquisitions to obtain high-resolution cross-sectional images of vessel detail.
(9) In addition to oncogenes, the transferred DNA contains genes that direct the synthesis and exudation of opines, which are used as nutrients by the bacteria.
(10) A total of 104 evaluable patients 20-90 years old treated by direct vision internal urethrotomy a.m. Sachse for urethral strictures reported retrospectively via a questionnaire their sexual potency before and after internal urethrotomy.
(11) However, direct measurements of mediator release should be carried out to reach a firm conclusion.
(12) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(13) These data indicate that RNA faithfully transfers "suppressive" as well as "positive" types of immune responses that have been reported previously for lymphocytes obtained directly from tumour-bearing and tumour-immune animals.
(14) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(15) The pancreatic changes are unlikely to be an artefact, but rather a direct toxic effect of the alcohol as confirmed by the biochemical changes.
(16) Errors in the initial direction of response were fewer in binocular viewing in comparison with monocular viewing.
(17) In the second approach, attachment sites of DTPA groups were directed away from the active region of the molecule by having fragment E1,2 bound in complex, with its active sites protected during the derivatization.
(18) The stages of mourning involve cognitive learning of the reality of the loss; behaviours associated with mourning, such as searching, embody unlearning by extinction; finally, physiological concomitants of grief may influence unlearning by direct effects on neurotransmitters or neurohormones, such as cortisol, ACTH, or norepinephrine.
(19) Completeness of isolation of the coronary and systemic circulations was shown by the marked difference in appearance times between the reflex hypotensive responses from catecholamine injections into the isolated coronary circulation and the direct hypertensive response from a similar injection when the circulations were connected as well as by the marked difference between the pressure pulses recorded simultaneously on both sides of the aortic balloon separating the two circulations.4.
(20) The direct monocyte source is not sufficient to insure the stability of this population.