(v. t.) To secure by bonds; to chain; to bond or confine; to hold tightly; to constringe.
(v. t.) To bring into a narrow compass; to compress.
(v. t.) To hold back by force; to restrain; to repress.
(v. t.) To compel; to force; to necessitate; to oblige.
(v. t.) To violate; to ravish.
(v. t.) To produce in such a manner as to give an unnatural effect; as, a constrained voice.
Example Sentences:
(1) Paul Johnson, the IFS director, said: “Osborne’s new fiscal charter is much more constraining than his previous fiscal rules.
(2) The parameters of the multiplet signal are consistent with the presence of a sterically constrained tyrosine phenoxyl radical.
(3) The variations in behavior and physiology across the year were considered in terms of factors constraining the timing of the natural reproductive pattern.
(4) First, chains are constrained by their inability to penetrate the boundary.
(5) The prepro form of ET-1 was inactive, suggesting that mature ET peptides are constrained in an inactive conformation within the preproET species.
(6) A method is presented for testing the equality of some or all (constrained or unconstrained) optima in a response surface analysis.
(7) The genius of a democracy governed by the rule of law, our democracy, is that it both empowers the majority through the ballot box, and constrains the majority, its government, so that it is bound by law.” Turnbull added: “Why does Daesh [another term for Islamic State] hate us?
(8) Often, a single, constrained peptide analogue can be designed, which will have many of the desired biological and biophysical properties, and will serve as a template.
(9) Because the rigor of the present day "scientific method" demands clearcut and reproducible results and investigations require predictable performance of the parasite in an evenly maintained host that is in a highly constrained environment, we should not wonder why we cannot produce the events of nature.
(10) In the first stage, the constrained random ordering of the stimuli is generated as specified by the user.
(11) Intrauterine influences which retard fetal weight gain may irrecoverably constrain the growth of the airways.
(12) "We have rhetorical pressure, which we are using, and we have the Seventh Fleet, which nobody wants to use, and in between our options are more constrained," he said.
(13) If correctional institutions constrain inmates' access to social benefits, means exist to protect incarcerated people's rights in health studies.
(14) Her ability to estimate time intervals and general time perspective was constrained by her impoverished store of knowledge for personal experiences.
(15) The immobilization successfully constrained the anteroinferior displacement of the maxilla and zygomatic bone on the fused side.
(16) In a previous study of push-off without plantar flexion it was shown that the transformation of knee angular velocity into translation of the body is constrained by the fact that velocity difference between hip and ankle has to reach its peak value a long time before the knee is extended.
(17) As there is no evidence for a close evolutionary link between kinesin and myosin, these and other similarities may represent convergence to set of common functional properties which are constrained by the requirements of protein structure and the use of ATP hydrolysis as a source of energy.
(18) By lengthening the ventricular effective refractory period, trains of conditioning stimuli could prevent or terminate tachycardias, but this possibility is constrained, at present, by the spatial limitations of the technique.
(19) The data suggest that the biological effects of RA may be constrained or augmented by differential regulation of its own receptor gene expression.
(20) A biological process serves as a source and its products are subject t] local dispersive fluid forces constrained by chaotic streamlines.
Loose
Definition:
(superl.) Not precise or exact; vague; indeterminate; as, a loose style, or way of reasoning.
(superl.) Unbound; untied; unsewed; not attached, fastened, fixed, or confined; as, the loose sheets of a book.
(superl.) Free from constraint or obligation; not bound by duty, habit, etc. ; -- with from or of.
(superl.) Not tight or close; as, a loose garment.
(superl.) Not dense, close, compact, or crowded; as, a cloth of loose texture.
(superl.) Not strict in matters of morality; not rigid according to some standard of right.
(superl.) Unconnected; rambling.
(superl.) Lax; not costive; having lax bowels.
(superl.) Dissolute; unchaste; as, a loose man or woman.
(superl.) Containing or consisting of obscene or unchaste language; as, a loose epistle.
(n.) Freedom from restraint.
(n.) A letting go; discharge.
(a.) To untie or unbind; to free from any fastening; to remove the shackles or fastenings of; to set free; to relieve.
(a.) To release from anything obligatory or burdensome; to disengage; hence, to absolve; to remit.
(a.) To relax; to loosen; to make less strict.
(a.) To solve; to interpret.
(v. i.) To set sail.
Example Sentences:
(1) Factors associated with higher incidence of rejection included loose sutures, traumatic wound dehiscence, and grafts larger than 8.5 mm.
(2) He is a leader and helps manage the defence, while Pablo Armero can be a bit of a loose cannon but he is certainly a talented player.
(3) This study investigates the use of the incentive inspirometer to observe the effects of tight versus loose clothing on inhalation volume with 17 volunteer subjects.
(4) Security forces have also tried to wrest back the Sunni stronghold of Tikrit from a loose alliance of Isis fighters, other jihadist groups and former Saddam Hussein loyalists.
(5) His shot, though, was pawed on to the inside of the post by David Marshall and it was left to Victor Wanyama to lash the loose ball into the empty net.
(6) We had our bicycles and we were just turned loose all day.
(7) Our model is a development of previous models, but differs in several respects: the overall activity is assumed to be dependent on the error level, the effect of errors in the translating system, giving rise to additional errors in the succeeding generation of products, is explicitly included as a special term in our model, and scavenging enzymes are assumed to break down and eliminate products with a loose structure.
(8) Clearance into the mediastinum may be the major pathway for liquid sequestered in the loose, binding connective tissue.
(9) Two tibial components (2%) were believed to be mechanically loose, but no revisions for mechanical loosening were done.
(10) The results indicate that the optimal cruciform loop size is four bases, with loose 'breathing' at the first base pair at the top of the cruciform stem at 37 degrees C, and little or no opening of base pairs at the four-way junction.
(11) Theresa May’s plan for a loose alliance with the Democratic Unionists to prop up her government was thrown into confusion on Saturday night after the Northern Ireland party contradicted a No 10 announcement that a deal had been reached.
(12) We have also confirmed loose linkage with the marker (Mfd22, locus D4S171) used to establish the initial assignment of the disorder to chromosome 4.
(13) As demonstrated by Ficoll density gradient centrifugation and HPLC gel filtration, the cholate dialysis method made the reductase bind tightly to the liposomal membranes, while the incubation with the preformed vesicles made the reductase bind loosely to the membranes.
(14) In its more loose, common usage, it's a game in which the rivalry has come to acquire the mad, rancorous intensity of a Celtic-Rangers, a Real Madrid-Barcelona, an Arsenal-Tottenham, a River Plate-Boca Juniors.
(15) Twenty-one of 24 adult male and female cattle egrets (Bubulcus ibis ibis) collected in Geneva County, Alabama had numerous white cyst-like structures (1,466 microns X 354 microns) found within the loose connective tissues of the skeletal muscles of the inguinal region, beneath the serosa of the proventriculus and in the heart beneath the epicardium (one adult male bird).
(16) SCLC variant lines could further be divided into (a) biochemical variant lines having variant biochemical profile but retaining typical SCLC morphology and growth characteristics; and (b) morphological variant (SCLC-MV) lines having variant biochemical profile, altered morphology (features of large cell undifferentiated carcinoma) and altered growth characteristics (growth as loosely attached floating aggregates, relatively short doubling times and cloning efficiencies).
(17) At rostral levels, one third of the tracts are loosely built forming a king of curtain, while they become more compact at caudal levels.
(18) (1) The prerequisite for development of cholesteatoma is a cholesteatoma bed, that is a loose subepithelial connective tissue layer which acts as a nutrient bed and makes papillary growth of squamous epithelium possible.
(19) His mother is Denise Welch, late of Corrie and Loose Women, and his father his Tim Healy, who was briefly famous 30 years ago for his role in Auf Wiedersehen, Pet.
(20) Initially, 4-5 days post-operative, the plasma clot maintained the grafted cells in a loose sponge-like sack at the site of implantation.