(v. t.) To secure by bonds; to chain; to bond or confine; to hold tightly; to constringe.
(v. t.) To bring into a narrow compass; to compress.
(v. t.) To hold back by force; to restrain; to repress.
(v. t.) To compel; to force; to necessitate; to oblige.
(v. t.) To violate; to ravish.
(v. t.) To produce in such a manner as to give an unnatural effect; as, a constrained voice.
Example Sentences:
(1) Paul Johnson, the IFS director, said: “Osborne’s new fiscal charter is much more constraining than his previous fiscal rules.
(2) The parameters of the multiplet signal are consistent with the presence of a sterically constrained tyrosine phenoxyl radical.
(3) The variations in behavior and physiology across the year were considered in terms of factors constraining the timing of the natural reproductive pattern.
(4) First, chains are constrained by their inability to penetrate the boundary.
(5) The prepro form of ET-1 was inactive, suggesting that mature ET peptides are constrained in an inactive conformation within the preproET species.
(6) A method is presented for testing the equality of some or all (constrained or unconstrained) optima in a response surface analysis.
(7) The genius of a democracy governed by the rule of law, our democracy, is that it both empowers the majority through the ballot box, and constrains the majority, its government, so that it is bound by law.” Turnbull added: “Why does Daesh [another term for Islamic State] hate us?
(8) Often, a single, constrained peptide analogue can be designed, which will have many of the desired biological and biophysical properties, and will serve as a template.
(9) Because the rigor of the present day "scientific method" demands clearcut and reproducible results and investigations require predictable performance of the parasite in an evenly maintained host that is in a highly constrained environment, we should not wonder why we cannot produce the events of nature.
(10) In the first stage, the constrained random ordering of the stimuli is generated as specified by the user.
(11) Intrauterine influences which retard fetal weight gain may irrecoverably constrain the growth of the airways.
(12) "We have rhetorical pressure, which we are using, and we have the Seventh Fleet, which nobody wants to use, and in between our options are more constrained," he said.
(13) If correctional institutions constrain inmates' access to social benefits, means exist to protect incarcerated people's rights in health studies.
(14) Her ability to estimate time intervals and general time perspective was constrained by her impoverished store of knowledge for personal experiences.
(15) The immobilization successfully constrained the anteroinferior displacement of the maxilla and zygomatic bone on the fused side.
(16) In a previous study of push-off without plantar flexion it was shown that the transformation of knee angular velocity into translation of the body is constrained by the fact that velocity difference between hip and ankle has to reach its peak value a long time before the knee is extended.
(17) As there is no evidence for a close evolutionary link between kinesin and myosin, these and other similarities may represent convergence to set of common functional properties which are constrained by the requirements of protein structure and the use of ATP hydrolysis as a source of energy.
(18) By lengthening the ventricular effective refractory period, trains of conditioning stimuli could prevent or terminate tachycardias, but this possibility is constrained, at present, by the spatial limitations of the technique.
(19) The data suggest that the biological effects of RA may be constrained or augmented by differential regulation of its own receptor gene expression.
(20) A biological process serves as a source and its products are subject t] local dispersive fluid forces constrained by chaotic streamlines.
Quench
Definition:
(v. t.) To extinguish; to overwhelm; to make an end of; -- said of flame and fire, of things burning, and figuratively of sensations and emotions; as, to quench flame; to quench a candle; to quench thirst, love, hate, etc.
(v. t.) To cool suddenly, as heated steel, in tempering.
(v. i.) To become extinguished; to go out; to become calm or cool.
Example Sentences:
(1) The extreme quenching of the dioxetane chemiluminescence by both microsomes and phosphatidylcholine, as a model phospholipid, implies that despite the low quantum yield (approx.
(2) The drug is extracted from serum or urine with ethyl acetate, separated by TLC, and determined by fluorescence quenching densitometry.
(3) Formation of a complex between alpha-tocopherol or its analogues in the excited state and fatty acids or their hydroperoxides has been suggested basing on the fluorescence quenching experimental data.
(4) Quenching of intrinsic fluorescence of (Ca2+-Mg2+)-ATPase by acrylamide, performed in the presence of Ca2+, gave evidence for a single class of tryptophan residues with Stern-Volmer constant (KSV) of 10 M-1.
(5) The 23Na double-quantum signal was quenched in both the extracellular and the intracellular compartments with increasing concentration of Li in each compartment, along with an increase in the 23Na T1 both intra- and extracellularly.
(6) Binding increases the fluorescence intensity of Tyr-49 by 130% while the fluorescence of the hormone tyrosine is almost completely quenched.
(7) Addition of 2,6-dimethylbenzoquinone caused quenching of these absorbance changes.
(8) These observations lead to the hypothesis that acidosis quenches fluorescence in distal skin flaps.
(9) The degree of quenching was accurately predicted by a simple relation derived in this paper, as well as a more complex equation previously developed by Tweet, et al.
(10) Subtilin may slightly enter the hydrophobic core as suggested by tryptophan fluorescence quenching and liposome fusion experiments.
(11) Greater than 99% of the polymerization reaction products were quenched by the addition of 2.0 mM ascorbate.
(12) Acoustic probe-based assays can enhance assay and laboratory efficiency through testing for multiple analytes in a single sample or increasing available binding surface area (by using probe and well surfaces simultaneously), and by eliminating quenching.
(13) The second-order rate constants appear to be at least 3 orders of magnitude lower than the second-order constants for quenching of the fluorescent probes; this is taken as a clear indication that ubiquinone diffusion is not the rate-determining step in the quinone-enzyme interaction.
(14) Accessibility to iodide was much lower, as was the rate of quenching by iodide, adding support to the conclusions from acrylamide quenching.
(15) An ATP-dependent, N-ethylmaleimide-inhibitable, 3,3',4',5-tetrachlorosalicylanilide-reversible, and chloride-attenuated quench of bis(1,3-dibutylbarbituric acid-(5] pentamethinoxonol fluorescence was seen, consistent with net transfer of positive charge into the vesicles.
(16) Quenching data indicated that five out of 22 tryptophans in CBH are surface-localized and are available for quenching with both KI and acrylamide, and three other tryptophans are buried and are available only to acrylamide.
(17) Acid quenching of a stiochiometric reaction between Ac(= S)CoA and citrate synthase following the transient quantitatively regenerates Ac(= S)CoA, indicating carbon-carbon bond formation had not yet occurred.
(18) The pulsed laser photolysis products of the charge-transfer quenching reaction were examined.
(19) The highest yield of amino acids with the quench reaction was 9 x 10-7 molecules per erg of input energy.
(20) Tris-washed chloroplast enriched in the photosystem II reaction center species Z+Q- and ZQ- are nearly four times more sensitive to nitrobenzene quenching than those enriched in Z+Q.