(n.) The act of constraining, or the state of being constrained; that which compels to, or restrains from, action; compulsion; restraint; necessity.
Example Sentences:
(1) Poor lipophilicity and extremely low plasma concentrations impose severe constraints.
(2) Specifically, we apply techniques of data preprocessing, orthogonality constraints, and validation of solutions in a complete TC analysis, for the first time using actual MEP data.
(3) When this constraint was released by various treatments altering membrane structure UDP-glucose markedly inhibited bilirubin glucuronidation.
(4) For each theory, a constraint on preformance is proposed based on interference between the "analytic" and "synthetic" pitch perception modes.
(5) spectroscopy for the collection of conformational constraints, calculation of the protein structure from the n.m.r.
(6) Subjects initially chose to work for the higher rated food, but as the constraints for this food increased, subjects chose to work for the lower rated food.
(7) Dictated by underlying physicochemical constraints, deceived at times by the lulling tones of the siren entropy, and constantly vulnerable to the vagaries of other more pervasive forms of biological networking and information transfer encoded in the genes of virus and invading microorganisms, protein biorecognition in higher life forms, and particularly in mammals, represents the finely tuned molecular avenues for the genome to transfer its information to the next generation.
(8) Continuing pressure on household finances during the next 12 months will no doubt remain a constraint."
(9) Lateralization may be an expression of reflex constraints bound initially to the infant's tonic-neck posture, with later development less reflex-patterned during the acquisition of more sophisticated information-processing strategies.
(10) His anti-politics act may just be a shtick – pretending he's still on Have I Got News for You, satirising politics even though he's right at the centre of it – but it liberates him from the usual constraints.
(11) Given that lattice constraints strongly inhibit large-scale conformational changes these results allow us to identify the average solution structure with the 'open' conformer determined crystallographically.
(12) A dynamic optimization technique to minimize jerk cost under the constraint on jerk input was applied to interpret the results, assuming that a major goal of skilled movements was to produce optimally smooth movements.
(13) Its main advantages, when compared to previously available programs using the variable target function algorithm, are a significant reduction of the computation time, and a novel treatment of experimental distance constraints involving diastereotopic groups of hydrogen atoms that were not individually assigned.
(14) For one, the ability to raise a larger deposit is acting as a constraint.
(15) When the constraints are high, a Michaelis-Menten equation can be used to model the kinetics for interfacial concentrations lower than the concentration leading to the maximum reaction rate.
(16) Estimators of the model parameters are defined under general exact and stochastic linear constraints.
(17) A careful reorganization of priorities would thus be helpful in improving neonatal care in Jamaica, even in the presence of financial constraints.
(18) Emergence and spread of antibiotic-resistant bacteria is augmented in settings in which treatment may be inadequate because of socioeconomic constraints and where there is crowding and poor sanitation.
(19) The estrogen receptor seems to have a moderate tolerance for bulky substituents: All of the halogen and halomethyl substituents bind with an affinity at least 50% that of estradiol; in the three atom alkyl series, the affinity declined markedly from propargyl (44%) and allyl (38%) to propyl (5%), suggestive of detailed steric constraints or a preference for unsaturation.
(20) Bias is controlled by the use of least-squares curve fitting for all assays, and constraints on the elimination of outlier points.
Constrict
Definition:
(v. t.) To draw together; to render narrower or smaller; to bind; to cramp; to contract or cause to shrink.
Example Sentences:
(1) There were two recurrent P. (1 Tbc, 1 viral) and no recurrent constriction.
(2) L660,711 had no significant effects on epinephrine- or vasopressin-induced arteriolar constriction.
(3) Myogenic constrictions and dilations was observed when IP was increased (greater than 60 cmH2O) and decreased (less than 60 cmH2O), respectively.
(4) Baroreflex function was studied in conscious early phase (less than 6 weeks) two-kidney, one-clip hypertensive rats before and 24 hours after surgical reversal of hypertension by removal of the constricting renal artery clip or after pharmacological reduction of blood pressure by an infusion of hydralazine or captopril.
(5) A series of hierarchical multiple regressions revealed the effects of Surgency, Agreeableness, Conscientiousness, Emotional Stability, and Intellect on evoking upset in spouses through condescension (e.g., treating spouse as stupid or inferior), possessiveness (demanding too much time and attention), abuse (slapping spouse), unfaithfulness (having sex with others), inconsiderateness (leaving toilet seat up), moodiness (crying a lot), alcohol abuse (drinking too much alcohol), emotional constriction (hiding emotions to act tough), and self-centeredness (acting selfishly).
(6) Neither the first- (A1) or second-order arterioles (A2) nor the first- (V1) or second-order venules (V2) constricted significantly to angiotensin II.
(7) When the same dose of ISO was administered to rats with aortic constriction the rise in labelled Ca uptake by the hypertrophied myocardium of the left ventricle was greatly reduced.
(8) We studied DNA (mtDNA) replication in adult female rat hearts undergoing hypertrophy secondary to constriction of the ascending aorta.
(9) 6 patients had thickened pericardium, and 3 had constrictive features.
(10) Clonidine and methysergide constrict the rabbit auricular artery by activating smooth muscle alpha-adrenoceptors.
(11) Electron microscopy in one case demonstrated typical intraneuronal accumulations of neurofilaments with regular constrictions.
(12) The rise in pressure approximated the sum of the rises caused by removal of the papilla alone and by renal artery constriction alone, consistent with the idea of two mechanisms being at work in this model.
(13) Transient peripheral vasomotor constriction and heart rate increases were initiated within an 8- to 12-sec period following target detection with the predictable schedule, with subjects evincing greater responsivity than their nonpredictable schedule counterparts.
(14) Data are constricted by the movement out of the area in the end stage of disease, which is only partially solved by tracking with community health workers.
(15) The in vivo synthesis rates of myosin isozyme heavy chains beta and alpha were measured in right ventricular (RV) muscle at 2 and 4 days following pulmonary artery constriction in rabbits, together with measurements of their relative mRNA levels.
(16) Aspiration is prevented by constriction of the thyroarytenoid muscle which provides a valved upper end of the tube.
(17) When tested in the guinea pig, 2a exhibited no effects on blood pressure and no broncho-constriction or dilation activity.
(18) However, certain other echocardiographic abnormalities of left ventricular posterior wall motion and interventricular septal motion and a high E-Fo slope were suggestive of constriction.
(19) The left anterior descending coronary artery of dogs and the right common carotid artery of rabbits were subjected to partial constriction with suture thread (40-60% reduction in transluminal diameter).
(20) A previously described laminectomy technique was modified by the addition of spinal plating to avoid the occurrence of constrictive fibrosis.