(n.) The act of constraining, or the state of being constrained; that which compels to, or restrains from, action; compulsion; restraint; necessity.
Example Sentences:
(1) Poor lipophilicity and extremely low plasma concentrations impose severe constraints.
(2) Specifically, we apply techniques of data preprocessing, orthogonality constraints, and validation of solutions in a complete TC analysis, for the first time using actual MEP data.
(3) When this constraint was released by various treatments altering membrane structure UDP-glucose markedly inhibited bilirubin glucuronidation.
(4) For each theory, a constraint on preformance is proposed based on interference between the "analytic" and "synthetic" pitch perception modes.
(5) spectroscopy for the collection of conformational constraints, calculation of the protein structure from the n.m.r.
(6) Subjects initially chose to work for the higher rated food, but as the constraints for this food increased, subjects chose to work for the lower rated food.
(7) Dictated by underlying physicochemical constraints, deceived at times by the lulling tones of the siren entropy, and constantly vulnerable to the vagaries of other more pervasive forms of biological networking and information transfer encoded in the genes of virus and invading microorganisms, protein biorecognition in higher life forms, and particularly in mammals, represents the finely tuned molecular avenues for the genome to transfer its information to the next generation.
(8) Continuing pressure on household finances during the next 12 months will no doubt remain a constraint."
(9) Lateralization may be an expression of reflex constraints bound initially to the infant's tonic-neck posture, with later development less reflex-patterned during the acquisition of more sophisticated information-processing strategies.
(10) His anti-politics act may just be a shtick – pretending he's still on Have I Got News for You, satirising politics even though he's right at the centre of it – but it liberates him from the usual constraints.
(11) Given that lattice constraints strongly inhibit large-scale conformational changes these results allow us to identify the average solution structure with the 'open' conformer determined crystallographically.
(12) A dynamic optimization technique to minimize jerk cost under the constraint on jerk input was applied to interpret the results, assuming that a major goal of skilled movements was to produce optimally smooth movements.
(13) Its main advantages, when compared to previously available programs using the variable target function algorithm, are a significant reduction of the computation time, and a novel treatment of experimental distance constraints involving diastereotopic groups of hydrogen atoms that were not individually assigned.
(14) For one, the ability to raise a larger deposit is acting as a constraint.
(15) When the constraints are high, a Michaelis-Menten equation can be used to model the kinetics for interfacial concentrations lower than the concentration leading to the maximum reaction rate.
(16) Estimators of the model parameters are defined under general exact and stochastic linear constraints.
(17) A careful reorganization of priorities would thus be helpful in improving neonatal care in Jamaica, even in the presence of financial constraints.
(18) Emergence and spread of antibiotic-resistant bacteria is augmented in settings in which treatment may be inadequate because of socioeconomic constraints and where there is crowding and poor sanitation.
(19) The estrogen receptor seems to have a moderate tolerance for bulky substituents: All of the halogen and halomethyl substituents bind with an affinity at least 50% that of estradiol; in the three atom alkyl series, the affinity declined markedly from propargyl (44%) and allyl (38%) to propyl (5%), suggestive of detailed steric constraints or a preference for unsaturation.
(20) Bias is controlled by the use of least-squares curve fitting for all assays, and constraints on the elimination of outlier points.
Curtail
Definition:
(v. t.) To cut off the end or tail, or any part, of; to shorten; to abridge; to diminish; to reduce.
(n.) The scroll termination of any architectural member, as of a step, etc.
Example Sentences:
(1) Second, interconversion of adenine nucleotides to guanine nucleotides, is curtailed by the inhibition of IMP dehydrogenase by these same IMP analogues.
(2) Stringent (rel+) as well as relaxed (rel minus) strains were able to rapidly curtail their accumulation of ribonculeic acid (RNA) after a downshift imposed by decreasing glucose transport into the cell.
(3) If a prisoner is in the process of taking a programme this can hinder or even curtail their progress – many prisons don't offer certain programmes so if you are moved to a prison without a particular course you are back to square one when it comes to the crucial Parole Board assessment.
(4) Egg (embryo) production was normal for mites treated with 0.50 krad, but significantly curtailed by doses of 0.75 krad and greater.
(5) Conservatives have called for federal funding to be curtailed if a municipality maintains a “sanctuary” policy.
(6) Which manager's playing career was curtailed by a knee injury sustained when he fell out of a tree while rescuing a cat?
(7) Three patients developed asymptomatic cystocele or enterocele, and 5 (23%) women had a curtailed vagina.
(8) Addition of H-7 to DiC8- and OAG-treated oocytes stimulated the pump activity curtailed by the two latters.
(9) It is suggested that umDC genes can be curtailed in their mutagenic activities but that they may still participate in some other, unknown process which provides the continued stimulus for their retention.
(10) After treatment with PTH, the enzyme reached maximal concentrations between 12-48 h, but declined to undetectable levels by 96 h. In contrast, the inhibitory activity was secreted in a linear fashion, with the highest concentrations achieved around 72-96 h. These results suggest a complex pattern of regulation of collagenase and inhibitor secretion by the osteoblastic cell, with the steady accumulation of inhibitor perhaps being responsible for the ultimate curtailment of enzyme activity.
(11) The former would point to entering serious negotiations with Labour, but the latter would ultimately curtail his flexibility towards Miliband, especially in relation to austerity.
(12) Citing the razor-thin margin by which the NSA's bulk phone-records collection survived a vote last week in the House of Representatives , Wyden and Udall vowed to continue their push to curtail the programme.
(13) Internal doubts can be managed, but external criticism in the social-media age is not so easy to curtail.
(14) Talking to officials and politicians, it's clear that Madrid's freedom over setting its own budgets and policies has also been curtailed.
(15) If the Karzai government does not take steps towards reducing corruption and improving capacity for governing in the next six to 12 months, the US should substantially curtail some categories of aid and assistance.
(16) Furthermore, in the absence of added KL, it greatly diminishes the erythropoietin- and interleukin-3-dependent BFU-E growth in BM; whereas in FL, a wider spectrum of inhibition is observed, with CFU-Mix most severely curtailed.
(17) Abdominal paradox has been proposed as a valuable clinical index of fatigue and thus its presence may lead to curtailment of weaning trials.
(18) Although this study does not suggest a synergistic relationship between smoking and oral contraception, it shows that both the adrenal gland and sympathetic nervous system's responses will be lowered if nicotine is curtailed.
(19) Research on their potential should not be curtailed because of fear that they will be subject to illicit abuse.
(20) An awareness of TOH facilities appropriate diagnosis and treatment and curtails unnecessary diagnostic procedures.