(n.) The act of constraining, or the state of being constrained; that which compels to, or restrains from, action; compulsion; restraint; necessity.
Example Sentences:
(1) Poor lipophilicity and extremely low plasma concentrations impose severe constraints.
(2) Specifically, we apply techniques of data preprocessing, orthogonality constraints, and validation of solutions in a complete TC analysis, for the first time using actual MEP data.
(3) When this constraint was released by various treatments altering membrane structure UDP-glucose markedly inhibited bilirubin glucuronidation.
(4) For each theory, a constraint on preformance is proposed based on interference between the "analytic" and "synthetic" pitch perception modes.
(5) spectroscopy for the collection of conformational constraints, calculation of the protein structure from the n.m.r.
(6) Subjects initially chose to work for the higher rated food, but as the constraints for this food increased, subjects chose to work for the lower rated food.
(7) Dictated by underlying physicochemical constraints, deceived at times by the lulling tones of the siren entropy, and constantly vulnerable to the vagaries of other more pervasive forms of biological networking and information transfer encoded in the genes of virus and invading microorganisms, protein biorecognition in higher life forms, and particularly in mammals, represents the finely tuned molecular avenues for the genome to transfer its information to the next generation.
(8) Continuing pressure on household finances during the next 12 months will no doubt remain a constraint."
(9) Lateralization may be an expression of reflex constraints bound initially to the infant's tonic-neck posture, with later development less reflex-patterned during the acquisition of more sophisticated information-processing strategies.
(10) His anti-politics act may just be a shtick – pretending he's still on Have I Got News for You, satirising politics even though he's right at the centre of it – but it liberates him from the usual constraints.
(11) Given that lattice constraints strongly inhibit large-scale conformational changes these results allow us to identify the average solution structure with the 'open' conformer determined crystallographically.
(12) A dynamic optimization technique to minimize jerk cost under the constraint on jerk input was applied to interpret the results, assuming that a major goal of skilled movements was to produce optimally smooth movements.
(13) Its main advantages, when compared to previously available programs using the variable target function algorithm, are a significant reduction of the computation time, and a novel treatment of experimental distance constraints involving diastereotopic groups of hydrogen atoms that were not individually assigned.
(14) For one, the ability to raise a larger deposit is acting as a constraint.
(15) When the constraints are high, a Michaelis-Menten equation can be used to model the kinetics for interfacial concentrations lower than the concentration leading to the maximum reaction rate.
(16) Estimators of the model parameters are defined under general exact and stochastic linear constraints.
(17) A careful reorganization of priorities would thus be helpful in improving neonatal care in Jamaica, even in the presence of financial constraints.
(18) Emergence and spread of antibiotic-resistant bacteria is augmented in settings in which treatment may be inadequate because of socioeconomic constraints and where there is crowding and poor sanitation.
(19) The estrogen receptor seems to have a moderate tolerance for bulky substituents: All of the halogen and halomethyl substituents bind with an affinity at least 50% that of estradiol; in the three atom alkyl series, the affinity declined markedly from propargyl (44%) and allyl (38%) to propyl (5%), suggestive of detailed steric constraints or a preference for unsaturation.
(20) Bias is controlled by the use of least-squares curve fitting for all assays, and constraints on the elimination of outlier points.
Engineer
Definition:
(n.) A person skilled in the principles and practice of any branch of engineering. See under Engineering, n.
(n.) One who manages as engine, particularly a steam engine; an engine driver.
(n.) One who carries through an enterprise by skillful or artful contrivance; an efficient manager.
(v. t.) To lay out or construct, as an engineer; to perform the work of an engineer on; as, to engineer a road.
(v. t.) To use contrivance and effort for; to guide the course of; to manage; as, to engineer a bill through Congress.
Example Sentences:
(1) Michael Schumacher’s manager hopes F1 champion ‘will be here again one day’ Read more Last year, Red Bull were frustrated by Mercedes, Ferrari and Honda as they desperately looked for a new engine supplier.
(2) The idea that 80% of an engineer's time is spent on the day job and 20% pursuing a personal project is a mathematician's solution to innovation, Brin says.
(3) Two EGZ-derived proteins were engineered in which either His98 or Glu133 amino acid was converted to an Ala residue.
(4) Liu was a driving force behind the modernisation of China's rail system, a project that included building 10,000 miles of high-speed rail track by 2020 – with a budget of £170bn, one of the most expensive engineering feats in recent history.
(5) Scott was born in North Shields, Tyne and Wear, the youngest of the three sons of Colonel Francis Percy Scott, who served in the Royal Engineers, and his wife, Elizabeth.
(6) Terry Waite Chair, Benedict Birnberg Deputy chair, Antonio Ferrara CEO The Prisons Video Trust • If I want to build a bridge, I call in a firm of civil engineers who specialise in bridge-building.
(7) Some 10 fire engines remained on the scene after rushing there to extinguish the many blazes caused by the crash.
(8) Engineering and physiologic aspects of growth and production processes associated with encapsulated cells, mostly of anchorage-independent type, are reviewed.
(9) Aircraft pilots Facebook Twitter Pinterest ‘Getting paid to have your head in the clouds.’ Photograph: CTC Wings Includes: Flight engineers and flying instructors Average pay before tax: £90,146 Pay range: £66,178 (25th percentile) to £97,598 (60th percentile).
(10) Based on the principles of adaptational mutations and genetic exchange of catabolic activities, it becomes possible to select and engineer microorganisms that are suitable for the degradation of recalcitrant compounds.
(11) The footballer said the noise of the engine was too loud to hear if Cameron snored but his night "wasn't the best".
(12) Top 10 Arpad Cseh Senior investment director, UBS Alice La Trobe Weston Executive director, head of European credit research, MSIM Morgan Stanley Katie Garrett Executive director, senior engineer, Goldman Sachs Alix Ainsley, Charlotte Cherry H R director, group operations (job share), Lloyds Banking Group Matt Dawson Director for business development, The Instant Group Angela Kitching, Hannah Pearce Head of external affairs (job share), Age UK Morwen Williams Head of newsgathering operations, BBC Georgina Faulkner Head of Sky multisports, Sky Maggie Stilwell Managing partner for talent, UK & Ireland, EY Sarah Moore Partner, PwC
(13) In what appeared to be pointed criticism of increasingly firm rhetoric from Cameron on multinational tax engineering, Carr insisted tax avoidance "cannot be about morality – there are no absolutes".
(14) If we were to have a plebiscite before the end of the year, and you were to reverse-engineer that, it would make interesting speculation about the timing of an election.” Abetz said in January he would need to see whether a plebiscite was “above board or whether the question is stacked” before deciding to heed any result in favour of marriage equality.
(15) "What this proves is that the way Bowie engineered his comeback was a stroke of genius," said music writer Simon Price.
(16) The carbohydrate structures of a genetically engineered human tissue plasminogen activator variant bearing a single N-glycosylation site at Asn 448 are reported.
(17) Senior executives at Network Rail are likely to be summoned to Westminster to explain the engineering overruns that caused chaos for Christmas travellers over the weekend.
(18) It will pump nothing more than water into the air, but it will allow climate scientists and engineers to gauge the engineering feasibility of the plan.
(19) Techniques of genetic engineering, homologous recombination, and gene transfection make it feasible to produce antigen-binding molecules with widely varying structures.
(20) This test was applied to hGH extracts produced genetically engineered E. coli K12 and a good correlation was found with the LAL test.