(n.) The act of constraining, or the state of being constrained; that which compels to, or restrains from, action; compulsion; restraint; necessity.
Example Sentences:
(1) Poor lipophilicity and extremely low plasma concentrations impose severe constraints.
(2) Specifically, we apply techniques of data preprocessing, orthogonality constraints, and validation of solutions in a complete TC analysis, for the first time using actual MEP data.
(3) When this constraint was released by various treatments altering membrane structure UDP-glucose markedly inhibited bilirubin glucuronidation.
(4) For each theory, a constraint on preformance is proposed based on interference between the "analytic" and "synthetic" pitch perception modes.
(5) spectroscopy for the collection of conformational constraints, calculation of the protein structure from the n.m.r.
(6) Subjects initially chose to work for the higher rated food, but as the constraints for this food increased, subjects chose to work for the lower rated food.
(7) Dictated by underlying physicochemical constraints, deceived at times by the lulling tones of the siren entropy, and constantly vulnerable to the vagaries of other more pervasive forms of biological networking and information transfer encoded in the genes of virus and invading microorganisms, protein biorecognition in higher life forms, and particularly in mammals, represents the finely tuned molecular avenues for the genome to transfer its information to the next generation.
(8) Continuing pressure on household finances during the next 12 months will no doubt remain a constraint."
(9) Lateralization may be an expression of reflex constraints bound initially to the infant's tonic-neck posture, with later development less reflex-patterned during the acquisition of more sophisticated information-processing strategies.
(10) His anti-politics act may just be a shtick – pretending he's still on Have I Got News for You, satirising politics even though he's right at the centre of it – but it liberates him from the usual constraints.
(11) Given that lattice constraints strongly inhibit large-scale conformational changes these results allow us to identify the average solution structure with the 'open' conformer determined crystallographically.
(12) A dynamic optimization technique to minimize jerk cost under the constraint on jerk input was applied to interpret the results, assuming that a major goal of skilled movements was to produce optimally smooth movements.
(13) Its main advantages, when compared to previously available programs using the variable target function algorithm, are a significant reduction of the computation time, and a novel treatment of experimental distance constraints involving diastereotopic groups of hydrogen atoms that were not individually assigned.
(14) For one, the ability to raise a larger deposit is acting as a constraint.
(15) When the constraints are high, a Michaelis-Menten equation can be used to model the kinetics for interfacial concentrations lower than the concentration leading to the maximum reaction rate.
(16) Estimators of the model parameters are defined under general exact and stochastic linear constraints.
(17) A careful reorganization of priorities would thus be helpful in improving neonatal care in Jamaica, even in the presence of financial constraints.
(18) Emergence and spread of antibiotic-resistant bacteria is augmented in settings in which treatment may be inadequate because of socioeconomic constraints and where there is crowding and poor sanitation.
(19) The estrogen receptor seems to have a moderate tolerance for bulky substituents: All of the halogen and halomethyl substituents bind with an affinity at least 50% that of estradiol; in the three atom alkyl series, the affinity declined markedly from propargyl (44%) and allyl (38%) to propyl (5%), suggestive of detailed steric constraints or a preference for unsaturation.
(20) Bias is controlled by the use of least-squares curve fitting for all assays, and constraints on the elimination of outlier points.
Exigency
Definition:
(n.) The state of being exigent; urgent or exacting want; pressing necessity or distress; need; a case demanding immediate action, supply, or remedy; as, an unforeseen exigency.
Example Sentences:
(1) It was the exigencies of World War II that brought about the 1st, largescale systematic promotion of condoms to prevent venereal disease.
(2) Therein lies the mission--and the obligation--of the Catholic hospital, which must continue into the future whatever new forms of organization exigencies may dictate.
(3) By similar methods rational, exigent therapeutic measures are selected (Table 5).
(4) The method was tested against the reference method using suspensions of C. Oedematiens (species demanding strictly anaerobiosis conditions), C. histolyticum (somewhat less exigent) and C. perfringens spores (mean esigence), seeding on the surface of dishes with Willis-Hobbs medium.
(5) At least some of the features of the principal and accessory submandibular glands of the vampire bat may be structural adaptations to the exigencies posed by the exclusively sanguivorous diet of these animals and its attendant extremely high intake of sodium chloride.
(6) Given the exigencies of the politics surrounding the Middle East peace process, only a fool would predict an outcome, not least with some diplomats in Washington assessing only a 10% chance of agreement on a framework document even by the April deadline.
(7) As long as government is allowed to collect all internet data, the perceived exigency will drive honest civil servants to reach more broadly and deeply into our networked lives.
(8) In addition to indicating that negative life situation exigencies, such as poor health and low income are related to lower well-being, the results tentatively indicate that these exigencies create a greater vulnerability to the impact of other negative conditions.
(9) Homosexual behavior among heterosexual women is discussed in terms of responses to different kinds of situational exigencies and the rationalizations used to deal with the experience while insulating the heterosexual self-identification.
(10) The exigencies of a disease-oriented strategy which requires a blend of therapeutic modalities many times require a modification of what would be an ideal modality-oriented strategy geared solely to effectively testing a new agent.
(11) The increasing frequency of chronic cholecystitis makes necessary a more minute diagnosis and exigent surgical indication, pledges for long-term favourable results.
(12) In contemporary psychiatry, neurobiological emphases and the exigencies of positivistic research have tended to standardize the picture of schizophrenia.
(13) Chris Mullin's most exigent friends would have relished its black comedy at a memorial service and then fallen, thanks to the Man Booker, upon an extraordinary saga that has yet to be promoted by Richard and Judy, the Grazia book club and Channel 4's TV Book Club .
(14) Long-run considerations, not short-run financial exigencies, should determine which activities occur in the private sector.
(15) New exigencies require new policies, and it's time to break with the past.
(16) Vertebrate egg envelopes, then, are basically similar; the modifications, including the addition of shell membranes and shells in some groups, reflect adaptations to differing reproductive strategies and to the environmental exigencies with which the egg must cope.
(17) There are five universal exigencies of being human, against which a person's existence can be evaluated: pairbondage, troopbondage, abidance, ycleptance, and foredoomance.
(18) Although the exigency level was not detailed, around 42% of the clinical trials sponsored by the pharmaceutical industry are performed according to GCP.
(19) He explains these deficiencies in terms of the exigencies of interdisciplinary work and the affinity of much early bioethics with policy- or legislatively-oriented "public ethics".
(20) To meet the exigencies of coping with the onset of schizophrenia in the family, caregivers sought out an array of professional and nonprofessional supports.