(n.) The act of constraining, or the state of being constrained; that which compels to, or restrains from, action; compulsion; restraint; necessity.
Example Sentences:
(1) Poor lipophilicity and extremely low plasma concentrations impose severe constraints.
(2) Specifically, we apply techniques of data preprocessing, orthogonality constraints, and validation of solutions in a complete TC analysis, for the first time using actual MEP data.
(3) When this constraint was released by various treatments altering membrane structure UDP-glucose markedly inhibited bilirubin glucuronidation.
(4) For each theory, a constraint on preformance is proposed based on interference between the "analytic" and "synthetic" pitch perception modes.
(5) spectroscopy for the collection of conformational constraints, calculation of the protein structure from the n.m.r.
(6) Subjects initially chose to work for the higher rated food, but as the constraints for this food increased, subjects chose to work for the lower rated food.
(7) Dictated by underlying physicochemical constraints, deceived at times by the lulling tones of the siren entropy, and constantly vulnerable to the vagaries of other more pervasive forms of biological networking and information transfer encoded in the genes of virus and invading microorganisms, protein biorecognition in higher life forms, and particularly in mammals, represents the finely tuned molecular avenues for the genome to transfer its information to the next generation.
(8) Continuing pressure on household finances during the next 12 months will no doubt remain a constraint."
(9) Lateralization may be an expression of reflex constraints bound initially to the infant's tonic-neck posture, with later development less reflex-patterned during the acquisition of more sophisticated information-processing strategies.
(10) His anti-politics act may just be a shtick – pretending he's still on Have I Got News for You, satirising politics even though he's right at the centre of it – but it liberates him from the usual constraints.
(11) Given that lattice constraints strongly inhibit large-scale conformational changes these results allow us to identify the average solution structure with the 'open' conformer determined crystallographically.
(12) A dynamic optimization technique to minimize jerk cost under the constraint on jerk input was applied to interpret the results, assuming that a major goal of skilled movements was to produce optimally smooth movements.
(13) Its main advantages, when compared to previously available programs using the variable target function algorithm, are a significant reduction of the computation time, and a novel treatment of experimental distance constraints involving diastereotopic groups of hydrogen atoms that were not individually assigned.
(14) For one, the ability to raise a larger deposit is acting as a constraint.
(15) When the constraints are high, a Michaelis-Menten equation can be used to model the kinetics for interfacial concentrations lower than the concentration leading to the maximum reaction rate.
(16) Estimators of the model parameters are defined under general exact and stochastic linear constraints.
(17) A careful reorganization of priorities would thus be helpful in improving neonatal care in Jamaica, even in the presence of financial constraints.
(18) Emergence and spread of antibiotic-resistant bacteria is augmented in settings in which treatment may be inadequate because of socioeconomic constraints and where there is crowding and poor sanitation.
(19) The estrogen receptor seems to have a moderate tolerance for bulky substituents: All of the halogen and halomethyl substituents bind with an affinity at least 50% that of estradiol; in the three atom alkyl series, the affinity declined markedly from propargyl (44%) and allyl (38%) to propyl (5%), suggestive of detailed steric constraints or a preference for unsaturation.
(20) Bias is controlled by the use of least-squares curve fitting for all assays, and constraints on the elimination of outlier points.
Restrain
Definition:
(v. t.) To draw back again; to hold back from acting, proceeding, or advancing, either by physical or moral force, or by any interposing obstacle; to repress or suppress; to keep down; to curb.
(v. t.) To draw back toghtly, as a rein.
(v. t.) To hinder from unlimited enjoiment; to abridge.
(v. t.) To limit; to confine; to restrict.
(v. t.) To withhold; to forbear.
Example Sentences:
(1) Cantact placing reaction times were measured in cats which were either restrained in a hammock or supported in a conventional way.
(2) It was hypothesized that compensatory restraining influences of surrounding soft tissues prevented a more severe facial malformation from occurring.
(3) After restrained least-squares refinement of the enzyme-substrate complex with the riboflavin omitted from the model, additional electron density appeared near the pyrophosphate, which indicated the presence of an ADPR molecule in the FAD binding site of PHBH.
(4) During collection, the rat was restrained in a plastic holder where it was free to eat.
(5) He could be the target of more punishing wit, as when Michael Foot, noting a tendency to be tougher abroad than at home, called him "a belligerent Bertie Wooster without even a Jeeves to restrain him."
(6) The apparatus consists of three basic components; a set of 4 strain gauge platforms on which the quadruped is trained to stand, a restraining device to keep the animal positioned over the strain gauge platforms and two mobile plates which mechanically stimulate the left or the right forelimb to produce the placing movement.
(7) The proposed new law gives victims of violence access to redress and protection, including restraining orders, and it requires local governments to set up more shelters.
(8) The structure of Mn(III) superoxide dismutase (Mn(III)SOD) from Thermus thermophilus, a tetramer of chains 203 residues in length, has been refined by restrained least-squares methods.
(9) These linkages could functionally restrain or assist in homeostatically restoring organelles to their normal position after the rearrangement that accompanies the substantial shortening of smooth muscle cells.
(10) A full-body restraining device was constructed that permits the short-term recording of physiologic data (respiration, electrocardiogram, arterial blood pressure, and electroencephalogram) in unanesthetized rats.
(11) For example, a majority of the respondents (82.2%) believed that it was appropriate to keep a patient restrained lying flat in bed.
(12) The reduced Hill coefficients and enhanced oxygen affinity are assumed to be due to impairment of the inter-chain contacts, to restrained cooperative mobility, and heterogeneity of the coupling products.
(13) The mean body temperature of restrained toms declined during the first 150 min of RE and then stabilized.
(14) Today, I am working clinically with Sam*, who moved to Dimensions from an assessment and treatment unit where he was often physically restrained to prevent incidents of aggression.
(15) Out of the total of 333 deaths, 87 people had been restrained, most commonly being physically held down by officers.
(16) We also examined the effect of an external restraining force on tibial subluxation in the ACL deficient knee.
(17) There was no significant difference between apparent pA2 values of unstressed and restrained rats using pA2 regression line analysis.
(18) Perhaps an independent Scotland would offer a restrained alternative to Westminster's current slash and burn.
(19) For training, head restrained animals were oscillated on a turntable in front of an optokinetic pattern projected onto a cylindrical wall.
(20) Significant increases in Tre were observed in the no-behaviour and the semi-restrained groups during cold exposure.