What's the difference between contraindication and indication?

Contraindication


Definition:

  • (n.) An indication or symptom which forbids the method of treatment usual in such cases.

Example Sentences:

  • (1) This study demonstrates that 1) complete AV block is not a contraindication to the Fontan operation, 2) some patients may not require AV synchrony postoperatively for survival, and 3) postoperative atrial flutter or fibrillation may cease or be easier to control after the Fontan operation.
  • (2) Primary vaccination should be carried out as early as possible, while strictly observing the contraindications.
  • (3) In addition to the well established contra-indications to use, a past history of pelvic inflammatory disease or ectopic pregnancy, promiscuity, nulliparity and age less than 25 are now considered relative contraindications.
  • (4) In conclusion, this study does not establish any indication or any contraindication in terms of hepatic histopathology with the possible exception of hepatic venous thrombosis for the use of oral testosterone treatment in men with alcoholic cirrhosis.
  • (5) This result contraindicates a general permissive-requisite role for forebrain NE for the mammalian brain's plasticity during its critical periods.
  • (6) There is no contraindication to spontaneous delivery.
  • (7) Only 16% provided information on generic name, indications, dosage, adverse effects and contraindications.
  • (8) This is due to contraindications and, more important, noncompliance of patients.
  • (9) Posterior subglottic extension of glottic carcinoma has been a contraindication for partial laryngectomy because of the proximity of the cricoid cartilage.
  • (10) Pregnancy, hyperthyroidism and intolerances are given as contraindications.
  • (11) Instillation of a talc suspension with thoracostomy drainage is also a safe and effective technique and should be employed when tetracycline fails or is contraindicated.
  • (12) The IUD is contraindicated for women at increased risk of sexually transmitted diseases; sexual habits and especially occasional multiple partners are the single most important risk in the increased frequency of upper genital tract infections in IUD users.
  • (13) The participants strongly preferred the experimental leaflets to the approved leaflets, both with respect to accessibility of the contents (overall preference 78.1% v 17.8%) and ease of understanding the contraindications of drug use (90.2% v 73.7%).
  • (14) Cyclosporin-induced thrombotic microangiopathy is considered by many as a contraindication to subsequent therapy with cyclosporin.
  • (15) In conclusion, CSF spectrophotometry is a simple, fast, and extremely sensitive method, which in our opinion should be used routinely in the diagnosis of suspected subdural haematomas, if lumbar puncture is not contraindicated.
  • (16) While agreeing with Murphy that CPR is contraindicated in many LTC patients, Youngner rejects his proposal to exclude patients and family members from the decision making process, and to not inform them of the physician's unilateral DNR decision.
  • (17) Multiple previous admissions were particularly contraindicative for standard treatment.
  • (18) A rare obstetric contraindication to the use of vaginal prostaglandins for fetal demise is presented in the form of a case report.
  • (19) These drugs are contraindicated in patients with ulcers, with haematological diseases, and with severe cirrhosis.
  • (20) Therefore, controlled hypotension, being a sophisticated technique, requires handling by an experienced anesthetist well aware of contraindications and the need for adequate monitoring for prevention of tissue ischemia.

Indication


Definition:

  • (n.) Act of pointing out or indicating.
  • (n.) That which serves to indicate or point out; mark; token; sign; symptom; evidence.
  • (n.) Discovery made; information.
  • (n.) Explanation; display.
  • (n.) Any symptom or occurrence in a disease, which serves to direct to suitable remedies.

Example Sentences:

  • (1) Indicators for evaluation and monitoring and outcome measures are described within the context of health service management to describe control measure output in terms of community effectiveness.
  • (2) These data indicate a steady improvement in laboratory performance over the last 10 years.
  • (3) Isotope competition studies indicated that the pathway was regulated by isoleucine.
  • (4) The results indicated that neuropsychological measures may serve to broaden the concept of intelligence and that a brain-related criterion may contribute to a fuller understanding of its nature.
  • (5) These results indicated that the PG determination was the most accurate predictor of fetal lung well-being prior to birth among the clinical tests so far reported.
  • (6) The findings indicate that there is still a significant incongruence between the value structure of most family practice units and that of their institutions but that many family practice units are beginning to achieve parity of promotion and tenure with other departments in their institutions.
  • (7) The predicted non-Lorentzian line shapes and widths were found to be in good agreement with experimental results, indicating that the local orientational order (called "packing" by many workers) in the bilayers of small vesicles and in multilamellar membranes is substantially the same.
  • (8) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
  • (9) Electrophysiologic studies are indicated in patients with sustained paroxysmal ventricular tachycardia, ventricular fibrillation or aborted sudden death.
  • (10) In cardiac tissue the adenylate system is not a good indicator of the energy state of the mitochondrion, even when the concentrations of AMP and free cytosolic ADP are calculated from the adenylate kinase and creatine kinase equilibria.
  • (11) Comparison of wild type and the mutant parD promoter sequences indicated that three short repeats are likely involved in the negative regulation of this promoter.
  • (12) Results indicated a .85 probability that Directive Guidance would be followed by Cooperation; a .67 probability that Permissiveness would lead to Noncooperation; and a .97 likelihood that Coerciveness would lead to either Noncooperation or Resistance.
  • (13) The data from this experience as well as others previously reported can yield prognostic indicators of survival in cases of accidental hypothermia.
  • (14) The data indicate that ebselen is likely to be useful in the therapy of inflammatory conditions in which reactive oxygen species, such as peroxides, play an aetiological role.
  • (15) This induction is sensitive to actinomycin D but not to protein synthesis inhibitor puromycin, indicating an effect of estradiol at the transcriptional level, possibly mediated by the estrogen receptor.
  • (16) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
  • (17) A disease in an IgD (lambda) plasmocytoma is described, where after therapy with Alkeran and prednisone a disappearance of all clinical and laboratory findings indicating an activity could be observed.
  • (18) Our results indicate that increasing the delay for more than 8 days following irradiation and TCD syngeneic BMT leads to a rapid loss of the ability to achieve alloengraftment by non-TCD allogeneic bone marrow.
  • (19) gamma-Aminobutyric acid (GABA) and glutamate release from the treated side was higher than the control value during the first 2-3 h, a result indicating an important role of glial cells in the inactivation of released transmitter.
  • (20) These results indicate that astrocytes possess bradykinin receptors and that these are predominantly of the B2 subtype.

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