(n.) An unnatural, violent, and unvoluntary contraction of the muscular parts of an animal body.
(n.) Any violent and irregular motion or agitation; a violent shaking; a tumult; a commotion.
Example Sentences:
(1) The results show that in TMO-treated animals the time to the onset of convulsions, the time to the onset of NADH oxidation-reduction cycles, and the survival time were significantly longer than in the control group.
(2) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(3) 1 Rats were convulsed once daily for 7 days by exposure to the inhalant convulsant agent, flurothyl (Indoklon, bis (2,2,2-trifluouroethyl)ether).
(4) Ruthenium red (RuR) inhibits Ca2+ uptake and transmitter release in synaptosomes, and produces flaccid paralysis when injected intraperitoneally (IP) and convulsions after intracranial administration.
(5) extended the survival time, even though all the mice died as a result of the convulsions.
(6) Facial twitch was followed by the generalized convulsion, further progressing to trembling of the limbs and then kicking of the hindlimb (full seizure) after 55 days of age.
(7) CZP reduced the incidence of convulsions only after the larger dose, but plain solvent (propylene glycol, ethanol, water) was equally effective.
(8) The relationship between the susceptibility to convulsions, the content of pyridoxal 5'-phosphate and the activity of pyridoxal kinase (EC 2.7.1.35) and glutamate decarboxylase (EC 4.1.1.15) in brain, was studied in the developing mouse.
(9) The convulsive episodes had several maxima during the abstinence period.
(10) A nervous syndrome characterized by clonic convulsive episodes inducible by exercise, developed at day 11.
(11) Anesthetic drugs have been each time defined pro or anti-convulsant: however, data from the literature show that it is not possible to certainly define the role of general anesthetics in the genesis of post-operative seizures.
(12) The risk of epilepsy after febrile convulsions is much less than reported in many hospital studies, and if febrile convulsions cause brain damage that leads to later epilepsy this is a rare occurrence.
(13) It was demonstrated that neither enflurane nor halothane exacerbates a pre-existing susceptibility to seizure activity and that both these inhalation anaesthetics are suitable for cases suffering from cerebral convulsive disorders.
(14) They were given individually to guinea pigs prior to poisoning with 2 x LD50 soman to test their efficacy against organophosphorus-induced convulsions, brain damage, and lethality.
(15) The antivasopressor analog d(CH2)5Tyr(Me) arginine-vasopressin completely blocked the convulsive-like behavior and other severe motor disturbances which are normally observed following a second central arginine-vasopressin injection.
(16) Venoruton offers a protection against hypoxic stress-induced neurotoxicity (convulsions and death) in mice.
(17) Evidence suggests that this lesion is probably a common cause of chronic epilepsy in adults and that often it is probably the result of a severe febrile convulsion in infancy.
(18) Using chick synaptic membranes, proteinaceous acceptors were characterized for dendrotoxin, a polypeptide from Dendroaspis angusticeps with convulsant activity due to its facilitation of transmitter release, resulting from inhibition of A-current K+ channels in brain.
(19) Compared with afebrile patients, PGE-2 levels were significantly higher after febrile convulsions.
(20) Seizures elicited by posture change and intraperitoneal administration of convulsants were studied ontogenetically in the Mongolian gerbil (Meriones unguiculatus).
Epileptic
Definition:
(a.) Pertaining to, affected with, or of the nature of, epilepsy.
(n.) One affected with epilepsy.
(n.) A medicine for the cure of epilepsy.
Example Sentences:
(1) Serum gamma glutamyl transferase (gammaGT) and alkaline phosphatase (ALP) activities have been estimated in 49 epileptic patients taking anticonvulsant drugs.
(2) In this series there were 45 patients (40%) with independent focal interictal EEG epileptic abnormalities over frontobasal cortex (with or without independent spiking over interomedial temporal region).
(3) Out of 50 epileptics in 31 cases temporal-lobe epilepsy was present, in 15 the seizures and EEG changes were generalized, in 4 cases focal non-temporal-lobe epilepsy was recognized.
(4) Among the epileptic patients investigated by the stereotactic E. E. G. (Talairach) whose electrodes were introduced at or around the auditory cortex (Area 41, 42), the topography of the auditory responses by the electrical bipolar stimulation and that of the auditory evoked potential by the bilateral click sound stimulation were studied in relation to the ac--pc line (Talairach).
(5) Lupus anticoagulant associated with thrombocytopenia, thrombosis or recurrent abortions was diagnosed in 2 epileptic patients chronically treated with anticonvulsant drugs.
(6) Eighteen adult epileptic patients under CBZ therapy were evaluated in this single-blind, randomized cross-over study.
(7) The threshold of epileptic spiking varied inversely with the area of cortical damage inflicted by the electrode.
(8) The large degree of inter-dose fluctuation between doses indicates that it is preferable to use pre-dose plasma sodium valproate levels to guide the clinical management of epileptic patients.
(9) These topographies enabled us to observe serial changes in epileptic discharge dynamically by 1 msec.
(10) The additional value of these methods, especially of the intensive monitoring, lies also in the possibility of compiling new knowledge about semiology and electro-clinical correlation of epileptic seizures, possible trigger mechanisms and long-term therapeutic effects.
(11) In epileptic hippocampi, (n = 21) reactive synaptogenesis of mossy fibers into the inner molecular layer of the granule cell dendrites was demonstrated at the light microscopic and electron microscopic levels.
(12) A clinical and electroencephalographic study of 107 neurologically normal children with partial seizures was undertaken to verify the existence and determine the frequency of epileptic syndromes reported in selected populations.
(13) Results show that the SLFIA method is a useful means for the determination of blood concentration of VPA in epileptic patients.
(14) In patients under anti-epileptic therapy it is readily possible for the clinical picture to be concealed, and this may then result in irreversible damage due to the disturbance of metabolism remaining uninfluenced.
(15) Effects of epileptic discharge on the autonomic nervous system are mediated through the cortical, limbic, and hypothalamic systems.
(16) Electroencephalographic activity and extracellular discharges from neurons in deep temporal lobe structures were recorded from fine wire microelectrodes chronically implanted in seven psychomotor epileptic patients for diagnostic localization of seizure foci.
(17) All these symptoms in these six patients disappeared completely or nearly completely after changing to another anti-epileptic drug or reducing the dose.
(18) The single dose pharmacokinetics of orally administered nimodipine (60 mg) were investigated in normal subjects and in two groups of epileptic patients receiving chronic treatment with hepatic microsomal enzyme-inducing anticonvulsants (carbamazepine, phenobarbitone or phenytoin) and sodium valproate, respectively.
(19) An essential complication in the cerebral cortex synaptic structure in the zone with a regular epileptic activity, as well as preservation of quantitative density of synapses near to the control level at epilepsy have been revealed.
(20) It is well established that children of mothers with epilepsy may suffer from facial clefts more frequently than children of non-epileptic mothers.