(1) When micF was cloned into a high-copy-number plasmid it repressed ompF gene expression, whereas when cloned into a low-copy-number plasmid it did not.
(2) On removal of selective pressure, the His+ phenotype was lost more readily than the Ura+ Trp+ markers, with a corresponding decrease in plasmid copy number.
(3) We have generated a series of mutants in the two copies of this motif present in human immunodeficiency virus type 1.
(4) The v-erb A oncogene of avian erythroblastosis virus is a mutated and virally transduced copy of a host cell gene encoding a thyroid hormone receptor.
(5) The fact that the security service was in possession of and retained the copy tape until the early summer of 1985 and did not bring it to the attention of Mr Stalker is wholly reprehensible,” he wrote.
(6) A method for constructing Ti plasmids bearing multiple copies of a sequence integrated in tandem is described.
(7) Overexpression of asparagine synthetase in beta-aspartyl hydroxamate-resistant lines without amplified copies of the gene was also correlated with DNA hypomethylation.
(8) This 54-bp fragment is present at about 2000-2500 copies in the bovine male genome.
(9) Construction of a repR-lacZ fusion proved that the increase in copy number was due to a proportional increase in the amount of RepR protein.
(10) The E2A mutants were propagated by growth in human cell lines which express an integrated copy of the DBP gene under the control of a dexamethasone-inducible promoter (D. F. Klessig, D. E. Brough, and V. Cleghon, Mol.
(11) The fusion was prepared in multicopy (pVLN102 plasmid) and low-copy-number states, the latter constructed as a lambda phage lysogen carrying a fur'-'lacZ insert.
(12) An expanded version of this paper, containing full experimental details of the semisynthesis and characterization of [GlyA1-3H]insulin, has been deposited as Supplementary Publication SUP 50129 (30 pages) at the British Library (Lending Division), Boston Spa, Wetherby, West Yorkshire LS23 7BQ, U.K., from whom copies can be obtained on the terms indicated in Biochem.
(13) All 51 undifferentiated NPCs contained significant numbers of EBV-genome copies per cell.
(14) By way of encouragement we've got 10 copies of Faber's smart new anniversary edition to give away.
(15) Programmed gene rearrangements are used in nature to to alter gene copy number (gene amplification and deletion), to create diversity by reassorting gene segments (as in the formation of mammalian immunoglobulin genes), or to control the expression of a set of genes that code for the same function (such as surface antigens).
(16) All three units are present in the same, probably single, copy number.
(17) Some derivatives of pIJ101, a 8.9 kb Streptomyces multi-copy plasmid, can co-exist with each other at similar copy numbers but others are strongly incompatible.
(18) Genomic southern hybridization experiments clearly indicate that the ribosomal RNA genes are unique single-copy DNA in H. cutirubrum.
(19) We demonstrate here that this transporter is encoded by a single family of tandemly clustered genes containing approximately 8 copies of the 3.6 kilobase repeat unit.
(20) There are approximately 20 copies of Tc1(Hin) amongst the Tc1's present in the Bergerac genome.
Quadruplicate
Definition:
(v. t.) To make fourfold; to double twice; to quadruple.
(a.) Fourfold; doubled twice; four times repeated; as, a quadruplicate ratio, or a quadruplicate proportion.
(a.) Raised to the fourth power.
Example Sentences:
(1) Three effector: target ratios (6.2:1, 25:1, and 50:1) were studied in quadruplicate using 3, 4 and 5-h incubations.
(2) The largest increases in brain weights in both sexes occurred during the first 3 years of life, when the value quadruples over that at birth, while during the subsequent 15 years the brain weight barely quintuples over that at birth.
(3) They then decreased very slowly, according to a half-life of 122 h. Although it decreases glomerular filtration, ligation of ureters 20 h before the injection quadrupled the concentration in the cortex.
(4) Official estimates suggest the number of small packages shipped into Europe more than quadrupled from 26m in 2000 to 115m two years ago.
(5) The kinetics of intravenously administered FK506 was not changed from control status two weeks after bile duct ligation, but the bioavailability of orally administered FK506 was nearly quadrupled.
(6) There is a clear benefit of quadruple drug induction treatment for retransplants and sensitized transplant candidates.
(7) This patient achieved a complete remission with cyclic quadruple chemotherapy consisting of cyclophosphamide, vincristine, procarbazine, and prednisone (COPP).
(8) Null yuh1 ubp1 ubp2 ubp3 quadruple mutants are viable and retain the ability to deubiquitinate ubiquitin fusions, indicating the presence of at least one more ubiquitin-specific processing protease in S. cerevisiae.
(9) Guinea pig alveolar macrophages were infected in quadruplicate with log10 3.8 CFU of F889 cells grown at either 25 or 41 degrees C. Counts of F889 in the alveolar macrophages infected with 25 degrees C-grown bacteria were 40% greater after 1 day of incubation (P = 2 X 10(-4)) than were counts in the alveolar macrophage suspensions inoculated with 41 degrees C-grown bacteria.
(10) Shares acquired through privatisations rose steadily on the stock markets, while the buyers of council houses found that their assets tripled or quadrupled in value in the space of five years.
(11) An inductively coupled, quadruple-tuned surface coil with a 50-ohm match at all relevant frequencies was used for both excitation and receiving.
(12) Although both stores carried the same brands and varieties of produce, all 19 cases occurred among employees of one store, which had held a celery sale coincident with the outbreak, resulting in a quadrupling of the usual volume of celery sold.
(13) during the period of one year, that triple and quadruple resistance is the most prevalent one in staphylococci - not regarded, however, the penicillin resistance which is absolutely predominant.
(14) Sequence differences in the internally quadruplicated molecules, analysed in terms of their beta-sheets, hairpins and arches, give rise to structural differences in the motifs.
(15) Furthermore, a high percentage of multiple (quadruple or more) pancreatica magna and caudae pancreatis arteries has been observed and a functional role of this peculiar arrangement is suggested.
(16) BEATING THE CHEATING Owen Gibson’s five-point plan for reform 1 Hugely increase global funding Triple it, quadruple it.
(17) Surgery consisted in quadruple coronary bypass in 1 case, triple coronary bypass in 3 cases and double coronary bypass in 6 cases using 4 autologous saphenous vein grafts, 6 autologous internal mammary artery grafts and 13 bovine internal mammary artery grafts.
(18) The price of the specially formulated milk he requires has quadrupled since last year, so his parents have had to rent out their own home and move into a much smaller, rundown one just to feed their child.
(19) The High Pay Commission revealed earlier this week that while average pay has quadrupled since 1980s, top executives have seen their remuneration rise by 4,000%.
(20) Fourteen patients (56%) had double, triple or quadruple cancers.