What's the difference between copy and issue?

Copy


Definition:

  • (n.) An abundance or plenty of anything.
  • (n.) An imitation, transcript, or reproduction of an original work; as, a copy of a letter, an engraving, a painting, or a statue.
  • (n.) An individual book, or a single set of books containing the works of an author; as, a copy of the Bible; a copy of the works of Addison.
  • (n.) That which is to be imitated, transcribed, or reproduced; a pattern, model, or example; as, his virtues are an excellent copy for imitation.
  • (n.) Manuscript or printed matter to be set up in type; as, the printers are calling for more copy.
  • (n.) A writing paper of a particular size. Same as Bastard. See under Paper.
  • (n.) Copyhold; tenure; lease.
  • (n.) To make a copy or copies of; to write; print, engrave, or paint after an original; to duplicate; to reproduce; to transcribe; as, to copy a manuscript, inscription, design, painting, etc.; -- often with out, sometimes with off.
  • (n.) To imitate; to attempt to resemble, as in manners or course of life.
  • (v. i.) To make a copy or copies; to imitate.
  • (v. i.) To yield a duplicate or transcript; as, the letter did not copy well.

Example Sentences:

  • (1) When micF was cloned into a high-copy-number plasmid it repressed ompF gene expression, whereas when cloned into a low-copy-number plasmid it did not.
  • (2) On removal of selective pressure, the His+ phenotype was lost more readily than the Ura+ Trp+ markers, with a corresponding decrease in plasmid copy number.
  • (3) We have generated a series of mutants in the two copies of this motif present in human immunodeficiency virus type 1.
  • (4) The v-erb A oncogene of avian erythroblastosis virus is a mutated and virally transduced copy of a host cell gene encoding a thyroid hormone receptor.
  • (5) The fact that the security service was in possession of and retained the copy tape until the early summer of 1985 and did not bring it to the attention of Mr Stalker is wholly reprehensible,” he wrote.
  • (6) A method for constructing Ti plasmids bearing multiple copies of a sequence integrated in tandem is described.
  • (7) Overexpression of asparagine synthetase in beta-aspartyl hydroxamate-resistant lines without amplified copies of the gene was also correlated with DNA hypomethylation.
  • (8) This 54-bp fragment is present at about 2000-2500 copies in the bovine male genome.
  • (9) Construction of a repR-lacZ fusion proved that the increase in copy number was due to a proportional increase in the amount of RepR protein.
  • (10) The E2A mutants were propagated by growth in human cell lines which express an integrated copy of the DBP gene under the control of a dexamethasone-inducible promoter (D. F. Klessig, D. E. Brough, and V. Cleghon, Mol.
  • (11) The fusion was prepared in multicopy (pVLN102 plasmid) and low-copy-number states, the latter constructed as a lambda phage lysogen carrying a fur'-'lacZ insert.
  • (12) An expanded version of this paper, containing full experimental details of the semisynthesis and characterization of [GlyA1-3H]insulin, has been deposited as Supplementary Publication SUP 50129 (30 pages) at the British Library (Lending Division), Boston Spa, Wetherby, West Yorkshire LS23 7BQ, U.K., from whom copies can be obtained on the terms indicated in Biochem.
  • (13) All 51 undifferentiated NPCs contained significant numbers of EBV-genome copies per cell.
  • (14) By way of encouragement we've got 10 copies of Faber's smart new anniversary edition to give away.
  • (15) Programmed gene rearrangements are used in nature to to alter gene copy number (gene amplification and deletion), to create diversity by reassorting gene segments (as in the formation of mammalian immunoglobulin genes), or to control the expression of a set of genes that code for the same function (such as surface antigens).
  • (16) All three units are present in the same, probably single, copy number.
  • (17) Some derivatives of pIJ101, a 8.9 kb Streptomyces multi-copy plasmid, can co-exist with each other at similar copy numbers but others are strongly incompatible.
  • (18) Genomic southern hybridization experiments clearly indicate that the ribosomal RNA genes are unique single-copy DNA in H. cutirubrum.
  • (19) We demonstrate here that this transporter is encoded by a single family of tandemly clustered genes containing approximately 8 copies of the 3.6 kilobase repeat unit.
  • (20) There are approximately 20 copies of Tc1(Hin) amongst the Tc1's present in the Bergerac genome.

Issue


Definition:

  • (n.) The act of passing or flowing out; a moving out from any inclosed place; egress; as, the issue of water from a pipe, of blood from a wound, of air from a bellows, of people from a house.
  • (n.) The act of sending out, or causing to go forth; delivery; issuance; as, the issue of an order from a commanding officer; the issue of money from a treasury.
  • (n.) That which passes, flows, or is sent out; the whole quantity sent forth or emitted at one time; as, an issue of bank notes; the daily issue of a newspaper.
  • (n.) Progeny; a child or children; offspring. In law, sometimes, in a general sense, all persons descended from a common ancestor; all lineal descendants.
  • (n.) Produce of the earth, or profits of land, tenements, or other property; as, A conveyed to B all his right for a term of years, with all the issues, rents, and profits.
  • (n.) A discharge of flux, as of blood.
  • (n.) An artificial ulcer, usually made in the fleshy part of the arm or leg, to produce the secretion and discharge of pus for the relief of some affected part.
  • (n.) The final outcome or result; upshot; conclusion; event; hence, contest; test; trial.
  • (n.) A point in debate or controversy on which the parties take affirmative and negative positions; a presentation of alternatives between which to choose or decide.
  • (n.) In pleading, a single material point of law or fact depending in the suit, which, being affirmed on the one side and denied on the other, is presented for determination. See General issue, under General, and Feigned issue, under Feigned.
  • (v. i.) To pass or flow out; to run out, as from any inclosed place.
  • (v. i.) To go out; to rush out; to sally forth; as, troops issued from the town, and attacked the besiegers.
  • (v. i.) To proceed, as from a source; as, water issues from springs; light issues from the sun.
  • (v. i.) To proceed, as progeny; to be derived; to be descended; to spring.
  • (v. i.) To extend; to pass or open; as, the path issues into the highway.
  • (v. i.) To be produced as an effect or result; to grow or accrue; to arise; to proceed; as, rents and profits issuing from land, tenements, or a capital stock.
  • (v. i.) To close; to end; to terminate; to turn out; as, we know not how the cause will issue.
  • (v. i.) In pleading, to come to a point in fact or law, on which the parties join issue.
  • (v. t.) To send out; to put into circulation; as, to issue notes from a bank.
  • (v. t.) To deliver for use; as, to issue provisions.
  • (v. t.) To send out officially; to deliver by authority; as, to issue an order; to issue a writ.

Example Sentences:

  • (1) You lot have got real issues to talk about and deal with.
  • (2) The issue of the Schizophrenia Bulletin is devoted to articles representing this full range of conceptual and empirical work on first-episode psychosis.
  • (3) I’m not in charge of it but he’s stood up and presented that, and when Jenny, you know, criticised it, or raised some issues about grandparent carers – 3,700 of them he calculated – he said “Let’s sit down”.
  • (4) Issues such as healthcare and the NHS, food banks, energy and the general cost of living were conspicuous by their absence.
  • (5) Before issuing the ruling, the judge Shaban El-Shamy read a lengthy series of remarks detailing what he described as a litany of ills committed by the Muslim Brotherhood, including “spreading chaos and seeking to bring down the Egyptian state”.
  • (6) Critics say he is unelectable as prime minister and will never be able to implement his plans, but he has nonetheless pulled attention back to an issue that many thought had gone away for good.
  • (7) Much of the current information concerning this issue is from short-term studies.
  • (8) It is entirely proper for serving judges to set out the arguments in high-profile cases to help public understanding of the legal issues, as long as it is done in an even-handed way.
  • (9) It has announced a four-stage programme of reforms that will tackle most of these stubborn and longstanding problems, including Cinderella issues such as how energy companies treat their small business customers.
  • (10) One man has died in storms sweeping across the UK that have brought 100-mile-an-hour winds and led to more than 50 flood warnings being issued with widespread disruption on the road and rail networks in much of southern England and Scotland.
  • (11) The issue has been raised by an accountant investigating the tax affairs of the duchy – an agricultural, commercial and residential landowner.
  • (12) They are just literally lying.” In August Microsoft severed its ties, saying Alec’s stance on climate change and several other issues “conflicted directly with Microsoft’s values”.
  • (13) One is that the issue of whether the World Cup should go ahead in Russia and Qatar still firmly remains on the table.
  • (14) The data indicate greater legitimacy and openness in discussing holocaust-related issues in the homes of ex-partisans than in the homes of ex-prisoners in concentration camps.
  • (15) That’s a criticism echoed by Democrats in the Senate, who issued a report earlier this month criticising Republicans for passing sweeping legislation in July to combat addiction , the Comprehensive Addiction and Recovery Act (Cara), but refusing to fund it.
  • (16) It can feel as though an official opinion has been issued.
  • (17) The first part of this survey which dealt with equipment for the anterior segment was published in a previous issue of this journal.
  • (18) Problem definition, the first step in policy development, includes identifying the issues, discussing and framing the issues, analyzing data and resources, and deciding on a problem definition.
  • (19) Heathrow, likewise, said Gatwick's new runway would not solve the issue of hub capacity.
  • (20) The deep green people who have an issue with the language of natural capital are actually making the same jump from value to commodification that they state that they don’t want ... They’ve equated one with the other,” he says.