(n.) The heart or inner part of a thing, as of a column, wall, rope, of a boil, etc.; especially, the central part of fruit, containing the kernels or seeds; as, the core of an apple or quince.
(n.) The center or inner part, as of an open space; as, the core of a square.
(n.) The most important part of a thing; the essence; as, the core of a subject.
(n.) The prtion of a mold which shapes the interior of a cylinder, tube, or other hollow casting, or which makes a hole in or through a casting; a part of the mold, made separate from and inserted in it, for shaping some part of the casting, the form of which is not determined by that of the pattern.
(n.) A disorder of sheep occasioned by worms in the liver.
(n.) The bony process which forms the central axis of the horns in many animals.
(v. t.) To take out the core or inward parts of; as, to core an apple.
(v. t.) To form by means of a core, as a hole in a casting.
Example Sentences:
(1) Even with hepatic lipase, phospholipid hydrolysis could not deplete VLDL and IDL of sufficient phospholipid molecules to account for the loss of surface phospholipid that accompanies triacylglycerol hydrolysis and decreasing core volume as LDL is formed (or for conversion of HDL2 to HDL3).
(2) Hoursoglou thinks a shortage of skilled people with a good grounding in core subjects such as maths and science is a potential problem for all manufacturers.
(3) Schneiderlin, valued at an improbable £27m, and the currently injured Jay Rodriguez are wanted by their former manager Mauricio Pochettino at Spurs, but the chairman Ralph Krueger has apparently called a halt to any more outgoings, saying: “They are part of the core that we have decided to keep at Southampton.” He added: “Jay Rodriguez and Morgan Schneiderlin are not for sale and they will be a part of our club as we enter the new season.” The new manager Ronald Koeman has begun rebuilding by bringing in Dusan Tadic and Graziano Pellè from the Dutch league and Krueger said: “We will have players coming in, we will make transfers to strengthen the squad.
(4) Core biopsy with computed tomography (CT) or ultrasound (US) guidance may be such an alternative, particularly when a spring-loaded firing device is used.
(5) Core enzyme, lacking omega subunit, catalyzed this reaction at a rate less than 1% that of holoenzyme.
(6) The specified region of the inner E2 core domain was highly homologous to the region of the E2 subunit of pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase.
(7) Each species has approximately 500 core histones cluster repeats per haploid genome.
(8) Thus there may be four types of LPS in PACI: one contains unsubstituted core polysaccharide and yields L2 on acid hydrolysis, another has short antigenic side-chains of the SR type and yields the LI fraction, while the two high molecular weight fractions are derived from core polysaccharides with different side-chains.
(9) Peptidoglycan synthesis is unaffected by the mutations affecting the core glycosyltransferases.
(10) The common atoms of the [3Fe-4S] and [4Fe-4S] cores agree within 0.1 A; the three common cysteinyl S gamma ligand atoms agree within 0.25 A.
(11) Tachycardia, pulmonary hypertension, increased venous oxygen desaturation, and increasing core temperature develop as the syndrome progresses.
(12) Some aspects of the life structure, of course, are also unconscious, namely, those having to do with attempted solutions to core personality conflicts and those reflecting modes of ego functioning.
(13) The interaction was specific for the DNA-binding activity of receptor, since H1 histones inhibit neither T3-binding activity nor core histone-binding activity of receptor.
(14) In contrast to the defect in another packaging-deficient mutant ts1201, the block in the formation of dense-cored, DNA-containing capsids in ts1233-infected cells at the NPT could not be reversed by transferring the cells to the permissive temperature in the presence of a protein synthesis inhibitor.
(15) Steady state levels of chloroplast mRNA encoding the core PSII polypeptides remain nearly constant in the light or the dark and are not affected by the developmental stage of the plastid.
(16) Viral particles in the cultures and the brain were of various sizes and shapes; particles ranged from 70 to over 160 nm in diameter, with a variable position of dense nucleoids and less dense core shells.
(17) The ternary complex consisting of a 65-kDa peptide originating from the proteoglycan core protein and a 43-kDa link protein bound to hyaluronic acid was purified from a clostripain digest of the rat chondrosarcoma aggregating proteoglycan and 14C-carbamylated with potassium [14C]cyanate.
(18) The binding of 125I-labeled core protein to immobilized fibronectin was inhibited by soluble fibronectin and by soluble cold core protein but not by albumin or gelatin.
(19) Intact wild-type cells, or those of a mutant in which the core region of the lipopolysaccharide was absent, were equally resistant to pronase treatment.
(20) The others had the structures galactosyl-galactosyl-xylosyl-4-methylumbelliferone and galactosyl-xylosyl-4-methylumbelliferone, respectively, representing the linkage region between the glycosaminoglycan chains and core protein, except that 4-methylumbelliferone replaced the amino acid.
Effect
Definition:
(n.) Execution; performance; realization; operation; as, the law goes into effect in May.
(n.) Manifestation; expression; sign.
(n.) In general: That which is produced by an agent or cause; the event which follows immediately from an antecedent, called the cause; result; consequence; outcome; fruit; as, the effect of luxury.
(n.) Impression left on the mind; sensation produced.
(n.) Power to produce results; efficiency; force; importance; account; as, to speak with effect.
(n.) Consequence intended; purpose; meaning; general intent; -- with to.
(n.) The purport; the sum and substance.
(n.) Reality; actual meaning; fact, as distinguished from mere appearance.
(n.) Goods; movables; personal estate; -- sometimes used to embrace real as well as personal property; as, the people escaped from the town with their effects.
(v. t.) To produce, as a cause or agent; to cause to be.
(v. t.) To bring to pass; to execute; to enforce; to achieve; to accomplish.
Example Sentences:
(1) Indicators for evaluation and monitoring and outcome measures are described within the context of health service management to describe control measure output in terms of community effectiveness.
(2) Previous use of the drug is found in more than 50 per cent of the patients, and it was often followed by a neglected side-effect.
(3) Circuit weight training does not exacerbate resting or exercise blood pressure and may have beneficial effects.
(4) Combinations of maximum amounts of glucagon and the cyclic nucleotide did not produce a greater effect than either agent alone.
(5) AEDs may also have differential effects on nighttime sleep.
(6) The effect of insulin-like growth factor I (IGF-I) on growth of small cell lung cancer (SCLC) cell lines was studied.
(7) This suggested that the chemical effects produced by shock waves were either absent or attenuated in the cells, or were inherently less toxic than those of ionizing irradiation.
(8) Combination therapy was most effective in patients receiving HCTZ prior to enalapril.
(9) Age difference did not affect the mean dose-effect response.
(10) The Na+ ionophore, gramicidin, had a small but significant inhibitory effect on Na(+)-dependent KG uptake, demonstrating that KG uptake was not the result of an intravesicular positive Na+ diffusion potential.
(11) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
(12) Increased plasmin activity was associated with advancing stage of lactation and older cows after appropriate adjustments were made for the effects of milk yield and SCC.
(13) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(14) Omission of K(+), Ca(++) or Mg(++) had no effect on uptake.
(15) Biochemical, immunocytochemical and histochemical methods were used to study the effect of chronic acetazolamide treatment on carbonic anhydrase (CA) isoenzymes in the rat kidney.
(16) Arachidic acid was without effect, while linoleic acid and linolenic acid were (on a concentration basis) at least 5-times less active than arachidonic acid.
(17) Simplicity, high capacity, low cost and label stability, combined with relatively high clinical sensitivity make the method suitable for cost effective screening of large numbers of samples.
(18) In dogs, cibenzoline given i.v., had no effects on the slow response systems, probably because of sympathetic nervous system intervention since the class 4 effects of cibenzoline appeared after beta-adrenoceptor blockade.
(19) The effects of sessions, individual characteristics, group behavior, sedative medications, and pharmacological anticipation, on simple visual and auditory reaction time were evaluated with a randomized block design.
(20) Urinary ANF immunoreactivity was significantly enhanced by candoxatril in both groups (P less than 0.05 and P less than 0.01 in groups 1 and 2, respectively), with a more pronounced effect evident at the higher dose (P less than 0.01).