(n.) The heart or inner part of a thing, as of a column, wall, rope, of a boil, etc.; especially, the central part of fruit, containing the kernels or seeds; as, the core of an apple or quince.
(n.) The center or inner part, as of an open space; as, the core of a square.
(n.) The most important part of a thing; the essence; as, the core of a subject.
(n.) The prtion of a mold which shapes the interior of a cylinder, tube, or other hollow casting, or which makes a hole in or through a casting; a part of the mold, made separate from and inserted in it, for shaping some part of the casting, the form of which is not determined by that of the pattern.
(n.) A disorder of sheep occasioned by worms in the liver.
(n.) The bony process which forms the central axis of the horns in many animals.
(v. t.) To take out the core or inward parts of; as, to core an apple.
(v. t.) To form by means of a core, as a hole in a casting.
Example Sentences:
(1) Even with hepatic lipase, phospholipid hydrolysis could not deplete VLDL and IDL of sufficient phospholipid molecules to account for the loss of surface phospholipid that accompanies triacylglycerol hydrolysis and decreasing core volume as LDL is formed (or for conversion of HDL2 to HDL3).
(2) Hoursoglou thinks a shortage of skilled people with a good grounding in core subjects such as maths and science is a potential problem for all manufacturers.
(3) Schneiderlin, valued at an improbable £27m, and the currently injured Jay Rodriguez are wanted by their former manager Mauricio Pochettino at Spurs, but the chairman Ralph Krueger has apparently called a halt to any more outgoings, saying: “They are part of the core that we have decided to keep at Southampton.” He added: “Jay Rodriguez and Morgan Schneiderlin are not for sale and they will be a part of our club as we enter the new season.” The new manager Ronald Koeman has begun rebuilding by bringing in Dusan Tadic and Graziano Pellè from the Dutch league and Krueger said: “We will have players coming in, we will make transfers to strengthen the squad.
(4) Core biopsy with computed tomography (CT) or ultrasound (US) guidance may be such an alternative, particularly when a spring-loaded firing device is used.
(5) Core enzyme, lacking omega subunit, catalyzed this reaction at a rate less than 1% that of holoenzyme.
(6) The specified region of the inner E2 core domain was highly homologous to the region of the E2 subunit of pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase.
(7) Each species has approximately 500 core histones cluster repeats per haploid genome.
(8) Thus there may be four types of LPS in PACI: one contains unsubstituted core polysaccharide and yields L2 on acid hydrolysis, another has short antigenic side-chains of the SR type and yields the LI fraction, while the two high molecular weight fractions are derived from core polysaccharides with different side-chains.
(9) Peptidoglycan synthesis is unaffected by the mutations affecting the core glycosyltransferases.
(10) The common atoms of the [3Fe-4S] and [4Fe-4S] cores agree within 0.1 A; the three common cysteinyl S gamma ligand atoms agree within 0.25 A.
(11) Tachycardia, pulmonary hypertension, increased venous oxygen desaturation, and increasing core temperature develop as the syndrome progresses.
(12) Some aspects of the life structure, of course, are also unconscious, namely, those having to do with attempted solutions to core personality conflicts and those reflecting modes of ego functioning.
(13) The interaction was specific for the DNA-binding activity of receptor, since H1 histones inhibit neither T3-binding activity nor core histone-binding activity of receptor.
(14) In contrast to the defect in another packaging-deficient mutant ts1201, the block in the formation of dense-cored, DNA-containing capsids in ts1233-infected cells at the NPT could not be reversed by transferring the cells to the permissive temperature in the presence of a protein synthesis inhibitor.
(15) Steady state levels of chloroplast mRNA encoding the core PSII polypeptides remain nearly constant in the light or the dark and are not affected by the developmental stage of the plastid.
(16) Viral particles in the cultures and the brain were of various sizes and shapes; particles ranged from 70 to over 160 nm in diameter, with a variable position of dense nucleoids and less dense core shells.
(17) The ternary complex consisting of a 65-kDa peptide originating from the proteoglycan core protein and a 43-kDa link protein bound to hyaluronic acid was purified from a clostripain digest of the rat chondrosarcoma aggregating proteoglycan and 14C-carbamylated with potassium [14C]cyanate.
(18) The binding of 125I-labeled core protein to immobilized fibronectin was inhibited by soluble fibronectin and by soluble cold core protein but not by albumin or gelatin.
(19) Intact wild-type cells, or those of a mutant in which the core region of the lipopolysaccharide was absent, were equally resistant to pronase treatment.
(20) The others had the structures galactosyl-galactosyl-xylosyl-4-methylumbelliferone and galactosyl-xylosyl-4-methylumbelliferone, respectively, representing the linkage region between the glycosaminoglycan chains and core protein, except that 4-methylumbelliferone replaced the amino acid.
Hinge
Definition:
(n.) The hook with its eye, or the joint, on which a door, gate, lid, etc., turns or swings; a flexible piece, as a strip of leather, which serves as a joint to turn on.
(n.) That on which anything turns or depends; a governing principle; a cardinal point or rule; as, this argument was the hinge on which the question turned.
(n.) One of the four cardinal points, east, west, north, or south.
(v. t.) To attach by, or furnish with, hinges.
(v. t.) To bend.
(v. i.) To stand, depend, hang, or turn, as on a hinge; to depend chiefly for a result or decision or for force and validity; -- usually with on or upon; as, the argument hinges on this point.
Example Sentences:
(1) The first experiment gave good results, although only one participant had any previous experience of hinge axis location, and it is debatable whether or not this experience is necessary before satisfactory results can be obtained.
(2) Brief digestion at neutral pH without reduction produced a molecule in which the Fab and Fc fragments were still linked by a pair of labile disulphide bridges, and the Fc fragment released by cleaving these bonds, called 1Fc fragment, contained a portion of the ;hinge' region including an interchain disulphide bridge.
(3) A modification of a previously described curved ruler, the current model has a hinge for greater ease of maneuverability and a "T" piece on one end to facilitate measurement and marking of both poles of the muscle without repositioning the ruler.
(4) In order to identify the specific carboxyl groups labeled by ETC, a purified cytochrome c1 preparation containing both the heme peptide and the hinge peptide was dimethylated at all the lysines to prevent internal cross-linking.
(5) The present report of a fatality from an external rearview mirror indicates the continued potential for harm from a projecting structure in spite of a hinged mounting and rounded shape.
(6) This investigation presents a commentary about two researches locating the terminal hing axis (THA) in totally edentulous people determined through the guided and not guided methods with chin compression.
(7) These variations indicate modulations of the tertiary structure, which may be due to a change of the L-hinge angle.
(8) In the alpha a and beta subunits they probably occur in the proline- and glycine-rich hinge region, which connects the head to the trunk.
(9) Roma are close to a deal for the Fiorentina winger Adem Ljajic and Tottenham's hopes of taking Lamela appear to hinge on it being finalised.
(10) This indicates that the enzyme does not affect the Ig molecule in the hinge region only.
(11) Whereas binding of monoclonal antibodies recognizing the tip and interface is abrogated or diminished, binding of antibodies to the hinge region is greatly enhanced following exposure of virus or the monomeric form of HA to pH 5.
(12) The position of NADP on beef liver catalase corresponds to the carboxyl-terminal polypeptide hinge in Penicillium vitale fungal catalase, which connects the common catalase structure to the additional flavodoxin-like domain.
(13) The popular appeal of the "School Shield" program hinges on believing in heroics; good public policy depends on preventing the need for them.
(14) However, our data also show the intron structure to be less stable than the mature tRNA domain, suggesting that the precursor may best be described as having two domains with a hinge at the junction of the anticodon and intron stems.
(15) Analysis of cysteine-containing peptides shows that the heavy chain of the IgG protein LEC has a deletion of residues 216-230, thus encompassing the entire hinge region.
(16) The time of disability (i.e., sick leave) was significantly shorter (6 weeks) with a hinged cast, but only in ACL cases.
(17) The results of a CT-anatomical correlative study of the main ligaments of the cervico-occipital hinge are reported.
(18) Neuroepithelial cells transform from spindle-shaped to wedge-shaped within the median and paired dorsolateral hinge points of the bending neural plate, but the mechanisms underlying these localized changes are unclear.
(19) This substitution may increase the flexibility of the molecule in the hinge region between the globular domain and the stalk.
(20) Although a higher salvage rate was obtained with the less-constrained prostheses, an infected hinge prosthesis did not preclude successful implant salvage.